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Results 201 - 250 of 2590
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Thomasen Jennifer M - - 2012
We investigated penetration patterns of monomeric and polymeric 1,6-hexamethylene diisocyanate (HDI), experimentally and as part of commercial products, in excised full-thickness human skin at 5, 10, 30, or 60 min after exposure. We observed that both monomeric and polymeric HDI were readily absorbed into the skin and that the clearcoat ...
Alcalá-Franco Beatriz - - 2012
OBJECTIVES: Hypermutable strains of Pseudomonas aeruginosa frequently emerge during chronic airways infection in cystic fibrosis (CF) patients. While the increased accumulation of mutations by hypermutable strains determines a biological cost for the colonization of secondary environments, the mutator phenotypes might confer a selective advantage under antibiotic treatment in a CF ...
Cui Kai - - 2012
We report on the achievement of, for the first time, InN/InGaN core/shell nanowire heterostructures, which are grown directly on Si(111) substrates by plasma-assisted molecular beam epitaxy. The crystalline quality of the heterostructures is confirmed by transmission electron microscopy, and the elemental mapping through energy dispersive x-ray spectrometry further reveals the ...
Atangana J - - 2012
We have comparatively studied the dynamics of malaria transmission in the villages of Mokolo-Douvar located in the rural area with traditional agriculture and Gounougou irrigated rice area, in 2004 August and November and 2006 May and October, to assess vectors biting habits, and malaria inoculation rate and malaria parasite prevalence ...
Emde Robert N - - 2012
Based on attachment theory, the construct of emotional availability and its assessment goes beyond attachment in important ways. Its origins in clinical experience and emotions research are discussed as well as the prospects for continuing advances in knowledge stimulated by the contributions in the Special Section. This is especially so ...
Carney Colleen E - - 2012
To present an expert consensus, standardized, patient-informed sleep diary. Sleep diaries from the original expert panel of 25 attendees of the Pittsburgh Assessment Conference(1) were collected and reviewed. A smaller subset of experts formed a committee and reviewed the compiled diaries. Items deemed essential were included in a Core sleep ...
Li Lianyong - - 2012
INTRODUCTION: Currently, the cover of the femoral head was mainly assessed using conventional plain films after Chiari pelvic osteotomy in most studies. The purpose of the current study was to observe whether the femoral head coverage measured by three-dimensional computed tomography (3D-CT) was consistent with the radiographic findings. PATIENTS AND ...
Zahel Tina - - 2012
Pulmonary carcinoids (PC) are separated into typical (TC) and atypical carcinoids (ATC). However, the biological behavior cannot be reliably predicted, and in small biopsies differential diagnosis can be challenging. To provide a basis for a grading approach, we analyzed mitoses and the proliferative index (PI; Ki-67) of 200 PC specimens ...
Kaya Selcuk - - 2012
Sepsis continues to be a very important cause of morbidity and mortality despite advances in modern medicine. It is the cause of mortality in approximately 28-50% of the patients, with the risk increasing particularly in patients with multiple organ dysfunctions. Although anti-infective treatment and securing hemostasis form the cornerstone in ...
Sekizawa Fumio - - 2012
The objective of this study was to investigate the relationship between the plasma concentrations of vitamin A (VA), vitamin E (VE) and β-carotene (BC) during embryo collection in Japanese Black cows that had undergone superovulation treatment and the embryo collection results. Following superovulation treatment in 116 Japanese Black cows, we ...
Eberl Markus M Department of Molecular Biology, University of Salzburg, Salzburg, - - 2012
Inhibition of Hedgehog (HH)/GLI signalling in cancer is a promising therapeutic approach. Interactions between HH/GLI and other oncogenic pathways affect the strength and tumourigenicity of HH/GLI. Cooperation of HH/GLI with epidermal growth factor receptor (EGFR) signalling promotes transformation and cancer cell proliferation in vitro. However, the in vivo relevance of ...
Kim Jung-Hee - - 2012
A sesquiterpene glycoside, cadin-2-en-1β-ol-1β-D-glucuronopyranoside (known as CR4-1), was isolated from Catharanthus roseus (Apocynaceae) hairy root cultures. C. roseus is widely used as an ornamental and medicinal plant and is cultivated mainly for its alkaloids. C. roseus has been reported to have pharmacologic properties such as anti-cancer, enzymatic anti-oxidant, and anti-diabetic ...
Koolen David A - - 2012
The 17q21.31 microdeletion syndrome is characterised by intellectual disability, epilepsy, distinctive facial dysmorphism, and congenital anomalies. To date, all individuals reported with this syndrome have been simplex patients, resulting from de novo deletions. Here, we report sibling recurrence of the 17q21.31 microdeletion syndrome in two independent families. In both families, ...
Thierry R - - 2012
Nanowire-based light-emitting devices require multi-quantum well heterostructures with high room temperature optical efficiencies. We demonstrate that such efficiencies can be attained through the use of ZnO/Zn((1-x))Mg(x)O core-shell quantum well heterostructures grown by metal organic vapor phase epitaxy. Varying the barrier Mg concentration from x = 0.15 to 0.3 leads to the formation ...
Wiggermann Philipp - - 2012
Thermal ablation procedures, including radiofrequency ablation (RFA) or laser-induced interstitial thermotherapy (LITT), are now well established in the treatment of malignant unresectable hepatic tumors. But the impact of partial ablation (PA) on long-term survival following computed tomography (CT)-guided radiofrequency ablation and laser- induced interstitial thermotherapy of unresectable malignant liver lesions ...
Aran Adi - - 2012
Hypocretin (orexin) is a unique neuropeptide involved in the consolidation of wakefulness and sleep. Although hypocretin-1 levels in the cerebrospinal fluid (CSF) are stable after infancy, how levels change in preterm and term human infants is unknown. Hypocretin-1 levels were measured in CSF samples, obtained from 284 preterm (25-37 gestational ...
Yan Chang - - 2012
Quaternary tetragonal Cu(2)FeSnS(4) nanocrystals have been synthesized by a simple hot-injection method. Detailed characterizations have been made. A suitable optical band gap of 1.28 ± 0.02 eV and a notable and stable photoelectrochemical response indicate their potential for application in solar cells.
Braham Imene - - 2012
Congenital galactosemia is a hereditary, autosomal recessive and metabolic disease. It is linked to an enzyme deficiency, more commonly known by the deficiency of galactose-1- phosphate uridyltransferase (GALT), which is responsible for an accumulation of galactose-1- phosphate in the blood. Clinical symptoms appear early in infancy from the second week ...
Nagarathinam Mangayarkarasi - - 2012
Grinding of a one-dimensional (1-D) ladder coordination polymer (CP), [Zn(μ-CH(3)CO(2))(CF(3)CO(2))bpe] (1), and a hydrogen-bonded 1-D CP, [Cd(CH(3)CO(2))(2)bpe(H(2)O)] (2), with KBr resulted in the exchange of carboxylate by bromide ions and the formation of 1-D zigzag and 2-D CPs respectively.
Alvarez Covadonga - - 2012
PURPOSE: The aim of this study was to compare the systemic exposure of lercanidipine (Zanidip) after oral administration in the fasted state and 15 min before food intake (meals) to investigate if the recommendations in the Summary of Product Characteristics (SPC) with respect to the intake of meals are adequate. METHODS: ...
Patel Mayurkumar B - - 2012
The inhibitory activity of Tinospora cordifolia stem-derived alkaloids was evaluated against lens aldose reductase (AR) isolated from male Wistar rats. Anticataract potential of the alkaloids of T. cordifolia was evaluated in vitro in rat lenses, considering the activity of normal rat lenses as 100%. The biologically active constituents of T. ...
Lecrux Clotilde - - 2012
Activation of the basal forebrain (BF), the primary source of acetylcholine (ACh) in the cortex, broadly increases cortical cerebral blood flow (CBF), a response downstream to ACh release. Although endothelial nitric oxide and cholinoceptive GABA (γ-aminobutyric acid) interneurons have been implicated, little is known about the role of pyramidal cells ...
Sowemimo Abimbola - - 2012
Context: Hedranthera barteri (Hook.f.) Pichon (Apocynaceae) is used traditionally in the treatment of convulsion in Southern Nigeria. Objective: The anticonvulsant activity of the methanol extract of H. barteri leaves was investigated. Materials and methods: The anticonvulsant activity of the extract (50,100 and 200 mg/kg, p.o.) was investigated in seizures induced by ...
Singha Biswajit - - 2012
PURPOSE: The purpose of the research is to investigate the applicability of the low-cost natural biosorbents for the removal of Pb(II) ions from aqueous solution and effluent from battery industry. METHODS: Six different biosorbents namely rice straw, rice bran, rice husk, coconut shell, neem leaves, and hyacinth roots have been ...
Hazebroek Mark - - 2012
For over 50 years viral infection has been recognized as an important trigger of acute myocarditis, inflammatory dilated cardiomyopathy (inflammatory DCM) and congestive heart failure. Nevertheless, viral heart disease remains challenging to diagnose and treat. Improved diagnostic methods for myocarditis have led to a better understanding of its pathophysiology. The ...
Yilmazoglu O - - 2012
We report a simple method for the micro-nano integration of flexible, vertically aligned multiwalled CNT arrays sandwiched between a top and bottom carbon layer via a porous alumina (Al(2)O(3)) template approach. The electromechanical properties of the flexible CNT arrays have been investigated under mechanical stress conditions. First experiments show highly ...
Bernal-Perez Lina F - - 2012
N-terminal acetylation of the recombinant Z-domain protein depends on E. coli strains, expression vectors and amino acid residues near the N-terminus, and is enhanced by a high cellular level of RimJ.
Singh Shweta - - 2012
The isolation of membrane proteins with the aim of producing highly pure, homogeneous, stable, and functional material remains challenging, and it is often necessary to develop protein-specific purification protocols by trial and error. One key tool that is required in the development of a suitable protocol is a functional assay. ...
Stanley John R - - 2012
Dermatologic disease, although seldom life threatening, can be extremely disfiguring and interfere with the quality of life. In addition, as opposed to other organs, just the aging of skin and its adnexal structure the hair follicle can result in cosmetic concerns that affect most of us. The articles in this ...
Schanz Jurik - - 2012
Hypercalcemia is a common problem in clinical practice and can be related to endocrine disorders or malignant disease, especially in elderly patients. Although rare, other causes can also be responsible. Granulomatous inflammation of the skin and lymph nodes induced by intravenous or injectable silicone is a rare condition of hypercalcemia ...
Reu S - - 2012
Mixed adenoneuroendocrine carcinomas (MANECs) are a challenge for the diagnostics and the concept of a histogenetic tumor typing. They are classified into three malignant subgroups: high grade malignant MANECs combine an adenoma or adenocarcinoma with a small cell or large cell neuroendocrine carcinoma, intermediate grade malignant MANECs consist of a ...
Robert Nadia - - 2012
In mammals, the Voltage-dependent anion channels (VDACs) are predominant proteins of the outer mitochondrial membrane (OMM) where they contribute to the exchange of small metabolites essential for respiration. They were shown to be as well associated with the plasma membrane (PM) and act as redox enzyme or are involved in ...
Graça Gonçalo - - 2012
We report on the first untargeted UPLC-MS study of 2nd trimester maternal urine and amniotic fluid (AF), to investigate the possible metabolic effects of fetal malformations (FM), gestational diabetes mellitus (GDM) and preterm delivery (PTD). For fetal malformations, considerable metabolite variations were identified in AF and, to a lesser extent, ...
Zheng Fang - - 2012
Abstract Microvesicles (MVs) are released by various cancer cells, including leukemia cells. They can "hijack" membrane components from their parental cells and exert pleiotropic effects on tumor progression. hERG1 K(+) channels are highly expressed in cancer cells and appear of exceptional importance in favoring cancer development. Given the attributes of ...
Huang Jun - - 2012
The paper reports an island nucleation and secondary growth of aligned ZnO : Cu nanorod arrays via thermal vapor phase transport. Results analysis indicates that the secondary segment is epitaxially grown on the ZnO : Cu nanorods with the radius strongly dependent on temperature and the concentration of zinc vapor. The modified characteristic radius ...
Hanczyc Piotr - - 2012
We report remarkable multiphoton absorption properties of DNA intercalating ruthenium complexes: (1) [Ru(phen)(2)dppz](2+); (2) [(11,11'-bidppz)(phen)(4)Ru(2)](4+); (3) [11,11'-bipb(phen)(4)Ru(2)](4+). Two-photon spectra in the range from 460 to 1100 nm were measured using the Z-scan technique. In particular, complex 2 was found to exhibit very strong two- and three-photon absorption properties, which could ...
Singh Shweta - - 2012
Functional characterization of G protein-coupled receptors is essential to ascertain the suitability of a protein target for downstream studies and to help develop optimal expression and isolation procedures. Radioligand binding analysis is a well-established technique, which allows direct measurement of the amount of functional receptor in a sample. It can ...
Vrachimis A - - 2012
Aim: Radioiodine remnant ablation (RRA) after (near-)total thyroidectomy (TE) is a key element in patients with differentiated thyroid cancer (DTC). The use of exogenous TSH stimulation (rhTSH) prior to RRA has shown promising results as compared to conventional thyroid hormone withdrawal (THW). As yet, the efficacy of RRA after brief ...
Higgins Paul G - - 2012
OBJECTIVES: The activity of BAL30072 was compared with that of anti-Acinetobacter reference drugs against meropenem-non-susceptible Acinetobacter baumannii isolates associated with up-regulation of the intrinsic OXA-51-like enzyme or an acquired OXA. METHODS: Antimicrobial susceptibility testing was investigated by broth microdilution of 310 non-duplicate, meropenem-non-susceptible A. baumannii isolates to BAL30072, amikacin ampicillin/sulbactam, ...
Tian Yufeng - - 2012
Spintronics, or spin-based data storage and manipulation technology, is emerging as a very active research area because of both new science and potential technological applications. As the characteristic lengths of spin-related phenomena naturally fall into the nanometre regime, researchers start applying the techniques of bottom-up nanomaterial synthesis and assembly to ...
Farahani Rouhollah Dermanaki - - 2012
This paper deals with the design and microfabrication of two three-dimensional (3D) freestanding patterned strain sensors made of single-walled carbon nanotube (SWCNT) nanocomposites with the ultraviolet-assisted direct-write (UV-DW) technique. The first sensor consisted of three nanocomposite microfibers suspended between two rectangular epoxy pads. The flexibility of the UV-DW technique enables ...
Shin Yiseul - - 2012
A series of solid solutions of polar aluminoborate materials, Al(5-x)Ga(x)BO(9) (0.0 ≤x≤ 0.5) have been synthesized by standard solid-state reactions using Al(2)O(3), Ga(2)O(5), and B(OH)(3) as reagents. The phase purities, crystal structures, and solid solution behavior of the reported materials have been investigated by powder X-ray diffraction. Solid solutions of ...
Myong Jun-Pyo - - 2012
Occupation can influence the prevalence of metabolic syndrome. Age and gender could interact with the association between occupation and metabolic syndrome. This study aimed to investigate the prevalence of metabolic syndrome among the Korean working population and determine whether the prevalence differed according to occupation, age and gender. We conducted ...
Blasco J - - 2012
We report the structural and magnetic properties of the La(1-x)Tb(x)Mn(1/2)Sc(1/2)O(3) series. LaMn(1/2)Sc(1/2)O(3) shows a long range ferromagnetic ordering in agreement with a fully polarized Mn-sublattice. The substitution of La with Tb produces structural changes which affect the magnetic properties. This substitution leads to a contraction in the unit cell volume ...
Vales Lori - - 2012
Accurate measurement of transvalvular pressure gradients is essential to comprehensively evaluate whether mechanical prosthetic valves are functioning normally. Direct measurements can be technically complicated, traditionally requiring direct, transapical puncture in the setting of both aortic and mitral mechanical valve prostheses. Very few case reports have proposed the use of guidewires ...
Wolf I - - 2012
Walking is a complex motor task generally performed automatically by older adults. Falls with or without serious consequences such as fractures or fear of falling can be the result. Gait analysis shows that even minor stride-to-stride variations increase the risk for falls. These gait changes are often too small to ...
Getachew A M - - 2012
A 12/13 kDa antigen, tapeworm ELISA test, developed for use in horses, was used to detect parasite-specific serum antibody, IgG(T), in the serum of donkeys. In a pilot study the 12/13 kDa antigen was tested and proved to detect the antibody, IgG(T), in donkey sera. Blood samples from 797 donkeys, naturally exposed ...
Meng Xiu-Jun - - 2012
Background: The Seventh Report of The Joint National Committee has recently introduced the prehypertension category of blood pressure (BP) status that needs monitoring and intervention. Little is known about the epidemiology of prehypertension in urban China, so this study aimed at estimating the prevalence of prehypertension and identifying risk factors ...
Bader Andrea - - 2012
The OR37 subfamily of odorant receptors (ORs) exists exclusively in mammals. In contrast to ORs in general, they are highly conserved within and across species. These unique features raise the question, whether olfactory information gathered by the OR37 sensory cells is processed in specially designated brain areas. To elucidate the ...
Karaca Zeki - - 2012
PURPOSE: For countries in which the stone industry is well developed, opposition to quarry and plant waste is gradually increasing. The primary step for waste control and environmental management is to define the problem of concern. In this study, natural building stone wastes were classified for the first time in ...
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