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Anand Akash G AG Department of Otolaryngology, Tulane University, New Orleans, LA 70112, - - 2012
Oropharyngeal reconstruction following head and neck oncologic resection has utilized local, regional, and free tissue transfer flap options. The modality utilized is often guided by the type of defect created as well as the surgeon's preference. In this article, the authors introduce the application of the supraclavicular artery island flap ...
Soltanian Hooman T HT Department of Plastic Surgery, University Hospitals Case Medical Center, Cleveland, Ohio 44106-5044, USA. - - 2012
Reconstruction of distal lower extremity defects often necessitates free tissue transfer. Because of its reliable vascular anatomy, pedicle length, and vessel size, the free rectus abdominis flap is widely used for this purpose. To minimize donor-site morbidity, several authors have described a segmental, or "partial," free rectus abdominis flap. After ...
Raghavan Shyam S SS Division of Plastic and Reconstructive Surgery, Stanford University Medical Center, Palo Alto, Calif., - - 2012
Tissue-engineered flexor tendon grafts may allow reconstruction of severe tendon losses. One critical factor is the optimization of cell proliferation and reseeding. Use of growth factors--basic fibroblast growth factor (bFGF), insulin-like growth factor (IGF)-1, and platelet-derived growth factor (PDGF)-BB--may improve culture conditions for human fibroblasts, tenocytes, and adipose-derived stem cells ...
Mulliken John B JB Department of Plastic and Oral Surgery, Children's Hospital Boston and Harvard Medical School, Boston, Mass. 02115, USA. - - 2012
Repair of unilateral cleft lip requires three-dimensional craftsmanship and understanding four-dimensional changes. Ninety-nine children with unilateral complete or incomplete cleft lip were measured by direct anthropometry following rotation-advancement repair (intraoperatively) and again in childhood. Changes in heminasal width, labial height, and labial width were analyzed and compared measures depending on ...
Khechoyan David D The Craniofacial Center, Seattle Children's Hospital, Seattle, Wash. 98105, - - 2012
There is controversy regarding whether the frontal bossing associated with sagittal synostosis requires direct surgical correction or spontaneously remodels after isolated posterior cranial expansion. The authors retrospectively measured changes in frontal bone morphology in patients with isolated sagittal synostosis 2 years after open posterior and midvault cranial expansion and compared ...
Verheyden Charles N CN Scott and White Healthcare, Texas A&M Health Science Center, Temple, Texas 76508, USA. - - 2012
The Code of Ethics of the American Society of Plastic Surgeons (ASPS) exists to encourage and enforce ethical behavior among its members. Complaints against individual members may be filed by patients or their representatives, members of the Society, or other members of the public. Data from a total of 677 ...
Chun Yoon S YS Division of Plastic Surgery, Department of Surgery, Harvard Medical School, Brigham and Women's Hospital, Boston, Mass. 02130, USA. - - 2012
Obesity, determined by body mass index, is known to be associated with surgical complications. This study was performed to evaluate a correlation between body mass index and postoperative complications in reduction mammaplasty. The authors performed a retrospective analysis of consecutive reduction mammaplasties performed at the Brigham and Women's Hospital by ...
Kobraei Edward M EM University of Kentucky College of Medicine, Lexington, KY, - - 2012
Attempts to identify risk factors for adverse outcome following skin-sparing mastectomy and immediate prosthetic reconstruction have yielded inconsistent results, and no clear patient selection criteria have emerged. The authors identified patient- and procedure-related characteristics that predict unfavorable postoperative outcomes. Knowledge of these risk factors will facilitate preoperative patient screening to ...
Hurwitz Zachary M ZM Department of Surgery, University of Massachusetts Medical School, Worcester, Mass. 01655, - - 2012
The α-gal epitope is a carbohydrate antigen that interacts specifically with the natural anti-Gal antibody--the most abundant antibody in humans. Anti-Gal/α-gal epitope interaction activates complement to generate chemotactic factors that induce rapid recruitment of macrophages. The authors hypothesized that α-gal epitopes on nanoparticles can accelerate wound healing by inducing rapid ...
Seth Akhil K AK Division of Plastic Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Ill., - - 2012
Bacterial biofilm is recognized as a major detriment to wound healing. The efficacy of traditional wound care against biofilm has never been studied. The authors evaluated the effect of clinical strategies against biofilm-infected wounds in a quantitative, in vivo model. Using a rabbit ear biofilm model, wounds were inoculated with ...
McGuire Lindsay K LK Memorial Sloan-Kettering Cancer Center, New York, NY 10022, - - 2012
Melanoma of the lentigo maligna subtype presents diagnostic and treatment challenges because of ill-defined clinical margins in cosmetically and functionally sensitive areas of the head and neck with extensive sun damage. This review highlights the natural history, varied clinical presentations, and pitfalls in histologic diagnosis. The focus is on the ...
Gunn J Stephen JS Division of Plastic Surgery, The Pennsylvania State University, College of Medicine, Hershey, PA 17033, - - 2012
Severed tendon repair advances with either a scar through extrinsic repair or regeneration through intrinsic repair. The authors examined whether intrinsic tendon repair reintroduces embryonic fibrillogenesis, whereby preformed collagen fibril segments are incorporated into growing collagen fibers at wound edges. Isolated tendons from 10-day-old chicken embryos were suspended in 1 ...
Maine Rebecca G RG Department of Surgery, University of California San Francisco, San Francisco, Calif., USA. - - 2012
International organizations have performed palatoplasties in low- and middle-income countries for decades, often working with local providers. Few studies report long-term outcomes, especially for palatal fistulas. A fistula after palatoplasty may affect speech, socialization, and nutrition. Fistula rates on surgical missions have not been compared with rates at U.S. craniofacial ...
Wolfram Dolores D Department of Plastic and Reconstructive Surgery, Innsbruck Medical University, Innsbruck, Austria. - - 2012
The authors investigated the immunological mechanisms underlying extensive peri-silicone implant capsule formation, one of the most frequent postoperative complications in patients receiving silicone mammary implants. The authors studied immune response activation by phenotypic and functional characterization of lymphocytes accumulated within this tissue. Intracapsular lymphoid cells and autologous peripheral blood mononuclear ...
Fattah Adel A Division of Plastic Surgery, The Hospital for Sick Children, Toronto, Ontario, - - 2012
This article outlines a thorough approach to facial nerve palsy and reconstruction.
Cordeiro Peter G PG Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. - - 2012
The objective of this study was to analyze early complications and long-term outcomes in patients undergoing salvage mastectomy and immediate tissue expander/implant reconstruction for cancer recurrence following breast conservation therapy (lumpectomy/irradiation). A review of all tissue expander/implant reconstructions performed by a single surgeon over an 11-year period from 1997 to ...
Ko Jason H JH Department of Surgery, Division of Plastic and Reconstructive Surgery, Northwestern University, Feinberg School of Medicine, Chicago, Ill., - - 2012
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, also known as statins, are the most commonly prescribed cholesterol-lowering medications in the world. Statins have been shown to inhibit connective tissue growth factor (CTGF) gene and protein expression in vitro, and previous studies in the authors' laboratory have demonstrated that CTGF plays a significant role ...
Abed Saif F SF Division of Basic Medical Sciences, St. George's University of London, London, England, United Kingdom. - - 2012
The cranio-orbital foramen is an osseous anatomical landmark located adjacent to the superior orbital fissure. It is a potential source of hemorrhage during deep orbital dissection because it is the location of an anastomosis between the lacrimal artery and the middle meningeal artery. The purpose of this study was to ...
Sunakawa Keisuke - - 2012
A multicenter, uncontrolled clinical study has been conducted to evaluate the safety, efficacy, and pharmacokinetics of liposomal amphotericin B (L-AMB) in children. In this article, the safety and efficacy of L-AMB are discussed. Subjects were diagnosed with invasive fungal infection (definitely diagnosed cases), possible fungal infection (clinically diagnosed cases), and ...
Ruiz Begoña - - 2012
OBJECTIVES: To translate and validate a Spanish version of the "Questionnaire on the treatment of approximal and occlusal caries" as a method of collecting information about treatment decisions on caries management in Chilean primary health care services. MATERIALS AND METHODS: The original questionnaire proposed by Espelid et al. was translated ...
Nakashima Kazutaka - - 2012
BACKGROUND: The current capacity of preoperative ultrasound examinations to estimate the intraductal spread of primary breast cancer was evaluated. The current ultrasound examination has three modes, B-mode, vascularity, and elastography, and this study evaluated this comprehensive ultrasound examination. METHODS: Of the patients undergoing breast cancer surgery for a breast mass ...
Saiki Hirofumi - - 2012
A full-term baby with double-outlet right ventricle and total anomalous pulmonary venous connection (TAPVC) complicated with left main pulmonary artery (PA) stenosis, presented with heart failure caused by increased pulmonary blood flow. Based on significant discrepancies in size and development between the left and right PAs, we performed right PA ...
Iparraguirre Arantza - - 2012
Membrane-assisted solvent extraction coupled to large volume injection in a programmable temperature vaporisation injector using gas chromatography-mass spectrometry analysis was optimised for the simultaneous determination of a variety of endocrine disrupting compounds in environmental water samples (estuarine, river and wastewater). Among the analytes studied, certain hormones, alkylphenols and bisphenol A ...
Cornwell Petrea - - 2012
OBJECTIVE: Non-malignant brain tumours have the potential to considerably affect functional outcomes and quality of life, with an associated significant burden for carers. There is a lack of knowledge about the care and support needs of patients with a brain tumour and their carers, in the early period following discharge ...
Scorza Fulvio Alexandre - - 2012
People with epilepsy are more likely to die prematurely, and the most common epilepsy-related category of death is sudden unexpected death in epilepsy (SUDEP). Thus, the purpose of this article was to alert the scientific community about SUDEP.
Kashimura Nobuichi - - 2012
PURPOSE: To clarify the impact of surgical site infection (SSI) after colorectal surgery on the length of hospital stay and medical expenditure in Japan. METHODS: This was a multi-center, retrospective-matched case-control study. RESULTS: The total number of patients enrolled was 334 (167 case/control pairs). The average hospital stay after surgery ...
Mochizuki Kiyofumi - - 2012
We report findings for a 74-year-old woman with Candida tropicalis endophthalmitis for whom an increase in β-D: -glucan level and worsening of endophthalmitis were observed after intravenous injection of micafungin, an echinocandin antifungal agent. Endogenous endophthalmitis caused by C. tropicalis developed in both eyes. On the basis of her surgical ...
Asai Nobuhiro - - 2012
Influenza related to complications such as pneumonia and encephalitis have sporadically been reported. However, influenza A (H1N1)-virus-associated hemophagocytic syndrome (VAHS) has rarely been reported. A 39-year old woman complained of high fever and was referred to us. Chest infiltrations in both lungs and a positive polymerase chain reaction (PCR) for ...
Kapustian Lyudmila L - - 2012
Recently, it has been suggested that some heat shock proteins such as Hsp70 and Hsp60 are involved in autoimmune diseases including cardiospecific ones. In this work we focused on the involvement of another well known heat shock protein, Hsp90, and its novel co-chaperone, Sgt1, in dilated cardiomyopathy (DCM). We found ...
Pereira Danilo Assis - - 2012
The Philadelphia Brief Assessment of Cognition (PBAC) is a neuropsychological screening instrument that assesses five cognitive domains: working memory, visuospatial functioning, language, episodic memory and comportment. The aim is to verify if PBAC can properly be used in the Brazilian sample. Participated in this study: (a) 200 healthy volunteers - ...
Sayyahfar Shirin - - 2012
Thyroid abscess is a rare event especially in the pediatric age group. We report a 2-year-old girl with thyroid abscess who presented with fever and an anterior painful neck mass. Culture of the aspirated fluid yielded Arcanobacterium haemolyticum, which is one of the etiologies of pharyngitis and rash in children ...
Ozer Kadri - - 2012
Achromobacter xylosoxidans (A. xylosoxidans) has been described as an opportunistic pathogen causing infection. The case we describe is that of an elderly man who had osteomyelitis of calcaneal bone caused by A. xylosoxidans. As far as we are aware there are only 5 cases of osteomyelitis with A. xylosoxidans in ...
Rabelo Daniel Rocha - - 2012
Background: Anomalous origin of coronary arteries is a relatively rare entity, which may show different clinical forms and develop an adverse outcome. Multislice coronary angiotomography has gained importance in daily clinical practice, representing an important patient assessment method with great potential in the anatomical evaluation of these arteries. Objective: This ...
Deganello A - - 2012
We describe a case of medial clavicular physeal separation with posterior displacement of the metaphysis in a 13-year-old girl, focusing on the role played by ultrasound in the diagnosis, planning of treatment and post-reduction follow-up. On clinical examination and conventional radiography, the injury is essentially indistinguishable from a sternoclavicular dislocation ...
Larson Noel C - - 2012
BACKGROUND: Type D personality is associated with recurrent coronary heart disease (CHD) risk but there is limited and inconsistent evidence regarding incident risk among persons free of clinical CHD. PURPOSE: We examined the association between Type D personality and coronary heart disease (CHD) risk in apparently healthy adults. We also ...
Yoshiya Shohei - - 2012
We herein describe an asymptomatic 31-year-old male who was admitted for an investigation of an abnormal pleural tumor detected by chest radiography. We performed various preoperative investigations including fluorodeoxyglucose-positron emission tomography. The maximum standardized uptake value (SUV(max)) was 2.2, and malignancy could not be ruled out. We therefore carried out ...
Swarbrick Joanna M - - 2012
Stable cyclic adenosine 5'-diphosphate ribose (cADPR) analogues are chemical biology tools that can probe the Ca(2+) release mechanism and structure-activity relationships of this emerging potent second messenger. However, analogues with an intact "northern" ribose have been inaccessible due to the difficulty of generating the sensitive N1-ribosyl link. We report the ...
Montenegro Márcio José MJ Instituto Estadual de Cardiologia Aloysio de Castro, Rio de Janeiro, Brasil. - - 2012
Atrial fibrillation is associated with embolic strokes that often result in death or disability. Effective in reducing these events, anticoagulation has several limitations and has been widely underutilized. Over 90% of thrombi identified in patients with atrial fibrillation without valvular disease originate in the left atrial appendage, whose occlusion is ...
Bitencourt Fernando F Instituto de Cardiologia do Rio Grande do Sul, Fundação Universitária de Cardiologia, Porto Alegre, RS, - - 2012
Hypertension is one of the major cardiovascular risk factors affecting more than one billion people. The low awareness of the disease is one of the greatest difficulties related to hypertension. The population screening for hypertension is widely recognized as an effective strategy to detect new cases, but until now, there ...
Ravindranath Mepur H - - 2012
HLA-E expressed on the surface of melanoma cells and shed into circulation are known to inhibit killing of tumor cells by binding to CD94/NKGA2 receptors on cytotoxic T- and NKT cells. Interferon (IFN)-γ is known to promote HLA-E over-expression on the cell surface and shedding. The shed HLA-E heavy chain ...
Yagi Keisuke - - 2012
Novel π-conjugated compounds composed of fused salphen groups as a repeating unit, embedded with four or an indefinite number of zinc nuclei have been synthesized. The solid-state absorption spectra, IR spectra, and powder XRD patterns of these compounds are investigated and compared with those of analogous oligomers. The presumptive polymer ...
Velicky Matej - - 2012
An analytical technique for the detection of permeation of a fully ionized analyte across a lipophilic membrane is reported. The system, which comprises of two aqueous compartments (donor and acceptor) separated by a supported liquid membrane, is based on the parallel artificial membrane permeation assay (PAMPA), widely used in the ...
Mondal Shovan - - 2012
The tandem Crabbé homologation-radical rearrangement of terminal enediynes leads, in a one-pot procedure, to the enantioselective synthesis of six- and seven-membered ring α-aminoesters bearing a quaternary stereocenter based on the phenomenon of memory of chirality.
Van Lierde Kristiane M - - 2012
The purpose of this study was to determine the presence, frequency, and intensity of pain during speaking in professional voice users and nonvocal professionals and to determine if the presence of pain is significantly related with the profile of the professional voice user. Based on the available literature, significantly more ...
Goñi Alejandro R - - 2012
For good performance of photonic devices whose working principle is based on the enhancement of electromagnetic fields obtained by confining light into dielectric resonators with dimensions in the nanometre length scale, a detailed knowledge of the optical mode structure becomes essential. However, this information is usually lacking and can only ...
Ho C-L - - 2012
A new heteroleptic iridium complex demonstrated low cytotoxicity and near-infrared excitation (via two-photon absorption) for target-specific in vitro Golgi imaging in various cell lines (HeLa and A549 cells) with two-photon absorption cross section (∼350 GM) in DMSO.
Gooren Louis J - - 2012
An analysis of variations in diagnosing and treating testosterone (T) deficiency between different regions of the world in 2006 was repeated in 2010. Physicians were interviewed in Germany, Spain, the United Kingdom, Brazil and Saudi Arabia about (1) reasons to use/not to use T. (2) safety (prostate pathology) and other ...
Ravera Mauro - - 2012
The synthesis and characterization of a series of picoplatin-based (picoplatin = [PtCl(2)(mpy)(NH(3))], mpy = 2-methylpyridine), Pt(iv) complexes with axial carboxylato ligands of increasing length are reported. The synthesis is based on the oxidation with hydrogen peroxide of picoplatin to give the cis,cis,trans-[PtCl(2)(mpy)(NH(3))(OH)(2)] intermediate and then its transformation into the dicarboxylato ...
- - 2012
OBJECTIVES: P2X3 receptors are expressed in trigeminal ganglia (TG) and participate in the transduction of facial pain. However, the mechanisms underlying P2X receptor-mediated nociception at different estrogen levels has not been examined. METHODS: In this study, female rats were randomly divided into sham-operated (sham), ovariectomized (OVX), and estrogen-treated groups. In ...
Zhu Chengzhou - - 2012
We demonstrated a simple, in situ reduction route to the synthesis of two-dimensional graphene oxide/SiO(2) (GSCN) hybrid nanostructures consisting of Au nanoparticles (Au NPs) supported on the both sides of GSCN. The as-prepared GSCN/Au NPs hybrid nanomaterials exhibited good catalytic activity for the reduction of 4-nitrophenol. This approach provided a ...
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