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Results 251 - 300 of 4033
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Azevedo Valderílio Feijó - - 2012
Tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine, and its excess can lead to severe consequences. Those effects are known to be antagonized by TNF-alpha inhibitors. Etanercept is a fusion protein that inhibits TNF-alpha action. As TNF-alpha regulation is related to cellular differentiation of various cellular types involved in immune ...
Tsai I-Ming - - 2012
A 19-year-old woman with skeletal Class III malocclusion, paranasal depression, and a low mandibular plane angle was treated with orthodontics and orthognathic surgery. Dental decompensation and protraction of maxillary right third molar to replace maxillary right second molar were performed before surgery. Clockwise rotation of maxillo-mandibular complex was applied by ...
Bohluli Behnam - - 2012
The nasal base is an important aspect of the nose with a complex anatomic architecture comprising a combination of cartilages, skin, connective tissues, and ligaments. Recent studies show that all nasal base deformities cannot be corrected by simple excision and suturing techniques. Alar release and medialization would be effective in ...
Spitale Naomi - - 2012
The ability to assess the inflammatory status of a patient's airway using a noninvasive method is the ideal situation for clinicians. Owing in part to the relationship between the levels of exhaled nitric oxide to inflammation and the ease of the technique, the measurement of the fraction of exhaled nitric ...
Kim Haeryoung - - 2012
Background/Aim: We aimed to investigate the prognostic value of biomarkers [Ki-67, adenosine triphosphate-binding cassette sub-family B member 1 (ABCB1), adenosine triphosphate-binding cassette sub-family C member 1 (ABCC1), adenosine triphosphate-binding cassette sub-family C member 2 (ABCC2), p53, cyclin E and v-akt murine thymoma viral oncogene homolog 2 (AKT2)] in patients with ...
Silver Wendy G - - 2012
Autism (autism spectrum disorders) is a complex, strongly genetically influenced, behaviorally defined disorder of the immature brain associated with very uneven intellectual abilities. Among its most salient and potentially treatable neurologic features that this article focuses on are epilepsy, disorganized sleep patterns, and sensory and motor deficits. Its many causes ...
Zaragoza-Macias Elisa - - 2012
The evaluation of cardiac masses is often a challenge for cardiac imaging techniques. The traditional standby has been two-dimensional echocardiography (2DE). Real time three-dimensional echocardiography (RT3DE) offers incremental value for the evaluation of intracardiac masses by providing more accurate assessment of the size and shape of the mass as well ...
Fragoso Thiago Sotero - - 2012
INTRODUCTION: The immunoregulatory role of vitamin D has been the object of a growing number of studies in patients with systemic lupus erythematosus (SLE). OBJECTIVES: To determine the serum levels of 25-hydroxyvitamin D3 [25(OH) D] in patients with SLE, and to assess the association of 25(OH)D insufficiency/deficiency with clinical parameters ...
Sun Zhuoyu - - 2012
Aim: The impact of micronutrient intake and colorectal cancer (CRC) risk is poorly understood. The objective of this study was to evaluate the associations of selected micronutrients with risk of incident CRC in study participants from Newfoundland, Labrador (NL) and Ontario (ON), Canada. We conducted a population-based study among 1760 ...
Chugani Diane C - - 2012
Positron emission tomography, single-photon emission tomography, and magnetic resonance spectroscopy (MRS) are powerful tools for the monitoring of diverse neurochemical functions. Neuroimaging studies targeting neurotransmitter systems in autism have provided clues about how differences in development of these systems might lead to new intervention approaches. Direct measurement of diverse neurochemicals ...
Farzanegan Fahimeh - - 2012
The aim of this study was to compare the efficacy of ibuprofen, viscoelastic bite wafers, and chewing gum in reducing orthodontic pain. This randomized clinical trial included 50 girls between the ages of 13 and 18 years classified into 5 groups of 10 each: placebo, ibuprofen (400 mg), chewing gum, ...
Beothe Tamas - - 2012
Mutation of the p53 gene has been implicated in the development of carcinoma in situ (CIS) to invasive solid urothelial carcinomas (UC) whereas loss of heterozygosity (LOH) at chromosome 9 has been suggested to plag part in the development of papillary UCs. The p53 mutation and LOH at chromosomes 17p13.1 ...
Koehler James - - 2012
As rhinoplasty techniques continue to evolve toward structural support and away from purely reductive techniques, the need for sophisticated grafting options will escalate to augment or replace critical support mechanisms of the nose. This will result in improved esthetic outcomes and functional results. We have found that well-planned and executed ...
Pompili Maurizio - - 2012
The objective of the study is to evaluate temporal trends, gender effects and methods of completed suicide amongst children and adolescent (aged 10-17) when compared with temporal trends of deaths from other causes. Data were extracted from the Italian Mortality Database, which is collected by the Italian National Census Bureau ...
Shimura Takaya - - 2012
Background/Aim: C-reactive protein (CRP) has been associated with the development of many carcinomas, but the significance of CRP remains unclear for metastatic gastric cancer (MGC). Sixty one patients who received S-1 plus cisplatin for MGC were retrospectively identified and categorized into two groups depending on the serum CRP level before ...
Nishimura Goshi - - 2012
Concurrent chemoradiotherapy (CCRT) is used to treat advanced head and neck cancer. The accuracy of evaluating lymph nodes metastases following CCRT is important for subsequent therapy. Patients were divided into two groups, the complete response (CR) and the non-CR groups, as determined by imaging and fine-needle aspiration cytology (FNAC) performed ...
Harrington Charles R - - 2012
Neurofibrillary pathology in Alzheimer's disease consists of paired helical filaments comprising tau protein. This pathology is correlated with dementia, but can appear in the first two decades of life. Extracellular amyloid β-protein arises through proteolytic processing of a transmembrane precursor, which involves the action of several enzymes. Mutations in the ...
Soares Neelkamal S - - 2012
Autism spectrum disorders (ASDs), also called pervasive developmental disorders in the Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition, Text Revised), constitute a group of neurodevelopmental disorders that coalesce around a common theme of impairments in social functioning, communication abilities, and repetitive or rigid behaviors. The ASDs considered here ...
Shirali Girish S - - 2012
Complex intracardiac anatomy and spatial relationships are inherent to congenital heart defects (CHDs). Recognition of the limitations of two-dimensional echocardiography has stimulated clinical interest in three-dimensional imaging. The current review examines contemporary studies in the following areas where three-dimensional echocardiography has provided additive value in CHD: (1) visualization of morphology, ...
Singh Meenu - - 2012
Reply to: Peters JL, Moreno SG, Phillips B, Sutton AJ. Are we sure about the evidence for zinc in prophylaxis of the common cold? Expert Rev. Respir. Med. 6(1), 15-16 (2012).
Cehreli Seçil - - 2012
The aim of this study was to evaluate the primary stability and the histomorphometric measurements of self-drilling and self-tapping orthodontic microimplants and the correlations between factors related to host, implant, and measuring technique. Seventy-two self-drilling and self-tapping implants were placed into bovine iliac crest blocks after computed tomography assessments. Insertion torque ...
Takagi Shunsuke - - 2012
To evaluate the relationship between body mass index (BMI) and blood pressure (BP) elevation during electroconvulsive therapy (ECT). Descriptive epidemiological study. Operating room of a university-affiliated hospital. All patients who received ECT at the Tokyo Metropolitan Hiroo Hospital from May 2005 to March 2009. All patients received routine ECT treatment. ...
Syrjänen K - - 2012
Since first suggested in 1979, evidence on the involvement of human papillomavirus (HPV) in bronchial carcinogenesis has been accumulated through several lines of research. The causal role of HPV in lung cancer still remains controversial, however, and more data are needed particularly on genotype distribution and cofactors of HPV regarding ...
Capstick Toby Gd - - 2012
Asthma and chronic obstructive pulmonary disease are both common conditions with an increasing prevalence worldwide. Inhaled therapy for these conditions has a number of advantages over systemic therapy, including reduced side effects and quicker onset of action. The effective use of inhaled therapy is critically dependent upon the nature of ...
Sarazin Marie - - 2012
In contrast with the previous criteria published in 1984 by the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association, the new criteria proposed in 2007 incorporated in the diagnostic framework the use of biomarkers that are able to assess the underlying ...
Kutilek Stepan - - 2012
INTRODUCTION: Raynaud's phenomenon (RP) is a paroxysmal and recurrent acral ischemia resulting from an abnormal arterial vasospastic response to cold or emotional stress. Homocysteine, a sulphured amino acid, has been linked to cardiovascular and neurodegenerative diseases, diabetes, thrombosis, and bone fragility. Homocysteine has been also linked to the pathogenesis of ...
Edel Elizabeth Morell - - 2012
Validating existing count practices and reducing individual practice variance are necessary to decrease the risk for retained surgical items. A quality improvement project was undertaken at one large city hospital to identify best practice and eliminate variability in count practices. The project included an analysis of 20 surgical count policies ...
Kaplan Gabriel - - 2012
At present, no evidence-based effective pharmacologic options are available for treating the core deficits of autism spectrum disorders (ASDs), which are best addressed by behavioral and educational interventions. However, such evidence exists for several of the frequently associated/comorbid symptoms such as aggression and severe irritability, hyperactivity, and repetitive behaviors, which ...
Chae Jong-Moon - - 2012
This case report describes the treatment of a boy, aged 13.6 years, whose ankylosed maxillary left central incisor had been avulsed and replanted 2.5 years earlier. Ankylosis of the tooth and adjacent alveolar process led to the development of infraocclusion, migration of adjacent teeth, midline deviation, and a vertical alveolar ...
Arcaro Giovanna - - 2012
The development of acute respiratory failure (ARF) secondary to respiratory tract infection is a common event in patients affected with osteogenesis imperfecta type III. Noninvasive positive pressure ventilation (NPPV) is increasingly administered to treat severe ARF of various origin. The use of NPPV in two patients with severe ARF secondary ...
Azevedo Mario Newton Leitão de - - 2012
OBJECTIVE: To assess the effect of the leukotriene receptor inhibitor (montelukast) on vascular alterations in fingers of patients with Raynaud's phenomenon. METHODS: Patients with Raynaud's phenomenon of the hands secondary to inflammatory connective tissue disease were selected, and those with the following characteristics were excluded: smokers, arterial hypertension, and diabetes ...
Nam Shin-Eun - - 2012
The purposes of this study were (1) to discover a simple method for computing an average dental form, (2) to evaluate the validity of the new computing method, and (3) to build an average digital dental model based on the resulting average dental form. Dental casts of 51 adults were ...
McKenzie Jodi A - - 2012
Melanoma is the deadliest form of skin cancer. Melanoma develops in response to genetic and environmental pressures which lead to oncogenic transformation of normal human melanocytes, the pigment-producing cells in the body. The majority of melanoma-associated deaths are due to metastases, highlighting the importance of understanding the molecular mechanisms driving ...
McCunn Maureen - - 2012
To assess the interest in and barriers to pursuing global health outreach (GHO) experiences for anesthesiology residents in the United States. Survey instrument. Academic department of anesthesiology. Anesthesiology residents who were members of the American Society of Anesthesiologists (ASA). An online survey was administered to residents in anesthesiology via the ...
Carr Kelly M - - 2012
Comprehension of informed consent information has been problematic. The purposes of this study were to evaluate the effectiveness of a shortened explanation of an established consent method and whether customized slide shows improve the understanding of the risks and limitations of orthodontic treatment. Slide shows for each of the 80 ...
Weiss Scott T - - 2012
Access to an electronic medical record is essential for personalized medicine. Currently, only 40% of US physicians have such access, but this is rapidly changing. It is expected that 100,000 Americans will have their whole genome sequenced in 2012. The cost of such sequencing is rapidly dropping, and is estimated ...
Hicks Rodney W - - 2012
Patient-controlled analgesia (PCA) is an effective treatment option for reducing pain, but PCA errors can be quite serious. Opioid analgesics are among the most effective pain relievers available, but all have contraindications and can have adverse effects, including respiratory depression and other effects on the central nervous system. Practitioners must ...
Shukuya Takehito - - 2012
Based on the results of phase I/II studies, S-1 plus cisplatin (CDDP) and vinorelbine (VNR) plus CDDP are commonly used chemoradiotherapeutic regimens for the treatment of non-small cell lung cancer(NSCCLC) in Japan. However, there have been no studies that have compared S-1 and CDDP combined with thoracic radiotherapy (TRT) with ...
Nazeer Ahsan - - 2012
The last decade has seen an increase of interest in autism spectrum disorders (ASD). With the prevalence now approaching 1%, children with ASD are usually first evaluated by clinicians working in primary care, such as pediatricians and family practitioners. Although classic autism is easy to recognize, differentiating autism from other ...
Rojas-Martínez Rosalba - - 2012
To compare the waist circumference cutoff points established by the American Heart Association and the National Heart, Lung and Blood Institute (AHA/NHLBI) with those of the International Diabetes Federation (IDF) for the screening of diabetes, hypertension, and metabolic syndrome in Mexican adults. This study comprised a subsample of the ENSANUT ...
Vomvas Dimitrios - - 2012
Aim: The main objective was to delineate the rates and clinical course of sexual function and depression in cancer patients undergoing radiotherapy. Forty-eight male and 90 female radiotherapy-naive outpatients with breast or pelvic cancer completed the International Index of Erectile Function (IIEF) or the Female Sexual Function Index (FSFI), and ...
Szczepanek Joanna - - 2012
Aim: Identification of signal transduction genes related to drug resistance in pediatric acute lymphoblastic leukemia (ALL). Ex vivo drug resistance in 107 children, divided into study and validation groups, was determined by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazoliumbromide (MTT) drug resistance assay. The gene expression profile was identified by microarray analysis and validated by ...
Jabbar Abdul - - 2012
Anisakidosis is an important fish-borne disease caused by the larvae of anisakid nematodes, which affects humans and a range of other animals. The accurate identification of members of this nematode group is central to investigating the epidemiology of the parasites and in the surveillance and control of anisakidosis. It is ...
Clarenbach Christian F - - 2012
The natural course of chronic obstructive pulmonary disease (COPD) is complicated by the development of systemic consequences and comorbidities. COPD has been associated with an increased risk for cardiovascular disease, osteoporosis, cachexia and skeletal muscle weakness. In several large prospective cohort studies, the degree of airflow limitation was an independent ...
Silva Tânia Lúcia de Oliveira - - 2012
OBJECTIVES: To evaluate the alveolar bone density (ABD) in the upper first molars of patients with juvenile idiopathic arthritis (JIA) and to compare their ABD with that of healthy controls. Secondary objectives included the evaluation of the influence of medication and rheumatic disease activity on ABD, in addition to the ...
Hockley Andrew - - 2012
Patient photos and silhouettes are commonly used in clinical evaluations and orthodontic research to evaluate profile esthetics. The purpose of this study was to determine whether the use of photos or silhouettes is a more appropriate method of evaluating African American profile esthetics and whether there are different profile esthetic ...
Orbach-Zinger Sharon - - 2012
To compare patient-controlled analgesia (PCA) with tramadol with PCA with remifentanil in second trimester abortion. Prospective, randomized double-blinded study University-affiliated medical center. 30 ASA physical status 1 and 2 patients undergoing a second trimester abortion. Patients received PCA with either tramadol or remifentanil. Analgesia was initiated in the tramadol group ...
Suarez Michelle A - - 2012
Children with autism experience many challenges that affect their ability to function. Sensory processing disorder and, specifically, sensory modulation disorder can compound dysfunction and further inhibit participation in productive activities. Through detection of and referral for sensory modulation disorders, treatment can be accessed. Emerging treatment evidence points to functional gains ...
Gea Joaquim - - 2012
Many respiratory diseases lead to impaired function of skeletal muscles, influencing quality of life and patient survival. Dysfunction of both respiratory and limb muscles in chronic obstructive pulmonary disease has been studied in depth, and seems to be caused by the complex interaction of general (inflammation, impaired gas exchange, malnutrition, ...
Hurt Arlen J - - 2012
Four relatively new technologies are now key in orthodontic specialty laboratories: digital photography, laser welding, computer-aided design/computer-aided manufacturing, and intraoral scanners. The purposes of this article are to briefly describe these technologies and to explain how they are used in the orthodontic laboratory.
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