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Soltanian Hooman T - - 2012
Reconstruction of distal lower extremity defects often necessitates free tissue transfer. Because of its reliable vascular anatomy, pedicle length, and vessel size, the free rectus abdominis flap is widely used for this purpose. To minimize donor-site morbidity, several authors have described a segmental, or "partial," free rectus abdominis flap. After ...
Grammatopoulos Ektor - - 2012
There is a popular belief among some musicians that playing a wind instrument regularly can affect the position of the teeth. The aim of this study was to investigate this hypothesis. A cross-sectional observational study was carried out, comparing the occlusions of 170 professional musicians selected from 21 orchestras and ...
Engelhardt Karin R - - 2012
Mucocutaneous candidiasis and dermatophyte infections occur either in isolation or alongside other symptoms in patients with various primary immunodeficiency diseases with diverse genetic defects, which result in impaired IL-17 immunity, IL-22 immunity, or both. In patients with chronic mucocutaneous candidiasis, disease-associated polymorphisms in DECTIN1 act on the level of fungal ...
Boedeker Ben H - - 2012
To compare the straight Magill and the curved Boedeker Intubation Forceps in foreign body removal in a manikin with a difficult airway using the videolaryngoscope. Prospective comparative study. University Medical Center. 17 medical providers, 16 anesthesia staff, and one respiratory therapist. The observed Cormack-Lehane (CL) glottic view and success/failure of ...
Nitta Yujiro - - 2012
For T1 stage incidental renal cell carcinoma (RCC), partial nephrectomy with or without laparoscopy is widely used on the basis of its nephron- sparing and minimally invasive nature. However, high-risk patients of advanced age, or with cardiovascular events are not often suitable candidates for surgery under general anesthesia. Percutaneous radiofrequency ...
Tartaglia Maria Carmela - - 2012
Frontotemporal dementia (FTD) describes a group of clinical syndromes united by underlying frontotemporal lobar degeneration (FTLD) pathology. The clinical syndromes associated with FTLD are heterogeneous and are based on whether the patients present with behavioral, language, or motor impairments. FTLD is at the center of a paradigm shift in neurodegenerative ...
Botello Igor - - 2012
In this study, in-line solid-phase extraction (SPE) was used as an enrichment technique in combination with CE for the preconcentration and separation of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), cocaine (COC), codeine (COD) and 6-acetylmorphine (6AM). The separation buffer (BGE) used was 80 mM disodium phosphate anhydrous and 6 mM of HCl (final BGE pH of ...
Abed Saif F - - 2012
: The cranio-orbital foramen is an osseous anatomical landmark located adjacent to the superior orbital fissure. It is a potential source of hemorrhage during deep orbital dissection because it is the location of an anastomosis between the lacrimal artery and the middle meningeal artery. The purpose of this study was ...
Caponnetto Pasquale - - 2012
The need for novel and more effective approaches to tobacco control is unquestionable. The electronic cigarette is a battery-powered electronic nicotine delivery system that looks very similar to a conventional cigarette and is capable of emulating smoking, but without the combustion products accountable for smoking's damaging effects. Smokers who decide ...
Nicholson I - - 2012
Objective: To identify the type and frequency of tracheostomy tube complications, and to determine factors associated with these complications, and with poor outcome. Methods: A database search for dogs undergoing temporary tube tracheostomy was performed. The medical records were scrutinised. The signalment, respiratory disease history, diagnosis, surgery, type and frequency ...
Schult Catrin - - 2012
Inhibition of signal transduction pathways has been successfully introduced into cancer treatment. The dual phosphatidylinositol 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor NVP-BEZ235 has antitumor activity in vitro against solid tumors. Here, we examined the activity of NVP-BEZ235 in acute lymphoblastic leukemia (ALL) cells and the best modalities ...
Nerguizian Vahé - - 2012
In a microbiological device, cell or particle manipulation and characterization require the use of electric field on different electrodes in several configurations and shapes. To efficiently design microelectrodes within a microfluidic channel for dielectrophoresis focusing, manipulation and characterization of cells, the designer will seek the exact distribution of the electric ...
Trejo-Valdivia Belem - - 2012
Determine Vaccination Coverage (VC) among adults 60 years of age and older (EP), for influenza, pneumococcal and tetanus vaccines, association with socio-demographic characteristics and heterogeneity at state level. Cross-sectional analysis based on information from 18 015 households visited in a national survey. General and vaccine information (self-report) for a randomly ...
Annecke Thorsten - - 2012
Propofol is widely used for sedating critically ill adult patients because of its rapid onset and short recovery times, even after prolonged use. Propofol may be associated with a life-threatening syndrome, propofol-related infusion syndrome (PRIS), which includes cardiac failure, severe metabolic acidosis, renal failure, and rhabodomyolysis. The pathophysiology is incompletely ...
Tao Chad - - 2012
Radiation therapy for primary and secondary liver cancer has been limited due to dose-limiting radiation-associated liver injury. Stereotactic body radiation therapy (SBRT) permits higher dose to tumors while minimizing radiation to uninvolved liver. The purpose of this study was to assess the efficacy and safety of SBRT for treating primary ...
Stühmer Thorsten - - 2012
HSP90 inhibitors effectively reduce expression and activity levels of oncogenic survival proteins. However, their clinical anti-multiple myeloma (MM) activity has been found to be rather weak, spurring the exploration of combination therapies and development of compounds with improved physicochemical properties. Preclinical effects of the novel orally bioavailable HSP90 inhibitor NVP-HSP990 ...
Duchan Erin - - 2012
Epidemiologic data gathered over the last 40 years report that the conservative estimate of autistic spectrum disorder prevalence is 27.5 per 10,000 individuals; however, the prevalence estimate based on newer surveys is 60 per 10,000 individuals. Several factors are considered in various epidemiologic surveys of autism, especially the evolution of ...
Kobraei Edward M - - 2012
Attempts to identify risk factors for adverse outcome following skin-sparing mastectomy and immediate prosthetic reconstruction have yielded inconsistent results, and no clear patient selection criteria have emerged. The authors identified patient- and procedure-related characteristics that predict unfavorable postoperative outcomes. Knowledge of these risk factors will facilitate preoperative patient screening to ...
Méndez-Hernández Pablo - - 2012
To assess the impact of a workplace leisure physical activity program on healthcare expenditures for type 2 diabetes and hypertension treatment. We assessed a workplace program's potential to reduce costs by multiplying the annual healthcare costs of patients with type 2 diabetes and hypertension by the population attributable risk fraction ...
Chittiboina Prashant - - 2012
This article reviews aspects of management of traumatic brain and spinal cord injury. A discussion of management of intracranial pressure after traumatic brain injury is followed by a discourse on cerebrovascular trauma and pediatric injuries. Specific management methods are discussed, including medical and surgical management in intracranial hypertension. A special ...
Martins Marielza Regina Ismael - - 2012
Fibromyalgia syndrome (FMS) is a painful condition of unknown etiology, highly prevalent, and associated with other conditions, which causes great impact on daily life and quality of life. OBJECTIVE: To assess, due to the multifactorial character of the FMS, the discriminating power of instruments used to identify good indicators of ...
Barone Angelo A Leto - - 2012
BACKGROUND:: Ex vivo introduction of an immunomodulatory transgene into a face or hand allograft may improve the risk-to-benefit ratio of vascularized composite allografts. Abrogation of the immunogenicity of the skin component of a face or hand allograft may decrease alloreactivity and permit the induction of immunologic tolerance. Proof-of-principle demonstrations of ...
Friedman Benjamin W - - 2012
Headaches are a common reason for visiting a health care provider. Headaches are at times symptomatic of an underlying process that requires prompt diagnosis and urgent treatment to reduce threats to life or limb. In this article, the authors review the 6 most common presentations for worrisome headache and discuss ...
Aras Banu - - 2012
The force application period is a modifiable factor in root resorption. There is still ambiguity if the continuity of force application is advantageous in terms of root resorption and tooth movement. In this prospective randomized clinical trial, we compared the effects of 2 reactivation periods of controlled-intermittent and continuous forces ...
Bunyan Reem F - - 2012
Central nervous system (CNS) inflammatory demyelinating diseases are a group of disorders that include multiple sclerosis, acute disseminated encephalomyelitis, and neuromyelitis optica. These conditions may result in emergencies because of severe inflammatory destruction of CNS tissues or complications thereof. Most of these conditions are responsive to appropriate therapy and early ...
Qaqish Clement - - 2012
We partition this discussion of revisional surgery based on perceived problems with the primary rhinoplasty. This will focus on either underresection or overresection of tissues and the ensuing clinical result. We also discuss some select problems associated with manipulation of tissues via suturing or grafting and briefly discuss functional considerations ...
Cordeiro Peter G - - 2012
The objective of this study was to analyze early complications and long-term outcomes in patients undergoing salvage mastectomy and immediate tissue expander/implant reconstruction for cancer recurrence following breast conservation therapy (lumpectomy/irradiation). A review of all tissue expander/implant reconstructions performed by a single surgeon over an 11-year period from 1997 to ...
Tusa Ronald J - - 2012
The cause of dizziness in patients seen in the emergency room can usually be determined by a focused evaluation that consists of identifying three key features in the history and five key elements of the clinical examination. This article discusses the most common causes of dizziness, how to use this ...
Molnár József - - 2012
The molecular basis of interaction of selected carotenoids and xanthophylls with ascorbic acid on cancer cells was studied to determine their anticancer effects. Drug accumulation was measured in a human ABCB1 gene-transfected mouse lymphoma cell line and in a human lung cancer cell line by flow cytometry; furthermore, their anticancer ...
Stevens Mark R - - 2012
Although anatomy often seems static, the continual innovation of new surgical techniques and approaches, in reality, make it a dynamic field. The first essential principal of any surgery is the comprehensive knowledge of the anatomic area and its physiology. This assertion is especially true in functional and or cosmetic nasal ...
Aizawa Sen-Ichi - - 2012
The mechanism of change in the enantiomer migration order (EMO) of tartarate on ligand exchange CE with Cu(II)- and Ni(II)-D-quinic acid systems was investigated thoroughly by circular dichroism (CD) spectropolarimetry. The (13) C NMR spectra of solutions containing D-quinate (pH 5.0) with Cu(II) or Ni(II) revealed the coordination of carboxylate ...
Taddei Silvana Rodrigues de Albuquerque - - 2012
Cytokines and chemokines regulate bone remodeling during orthodontic tooth movement. CC chemokine ligand 2 (CCL2) is involved in osteoclast recruitment and activity, and its expression is increased in periodontal tissues under mechanical loading. In this study, we investigated whether the CC chemokine receptor 2 (CCR2)-CCL2 axis influences orthodontic tooth movement. ...
Morimoto Manabu - - 2012
No reliable prognostic predictor is known for patients undergoing sorafenib treatment for advanced hepatocellular carcinoma (HCC). In 81 patients receiving sorafenib treatment for advanced HCC, we evaluated the prognostic significance of an inflammation-based prognostic score, the Glasgow prognostic score [evidenced by an elevated C-reactive protein level (>1.0 mg/dl) and hypoalbuminemia ...
Smith Francis Duval - - 2012
Surgical facilities often stock many types of bone and bone products to meet the needs of multiple surgeons. In this era of cost containment, product standardization is necessary for the financial well-being of health care facilities. By familiarizing themselves with bone and bone product harvesting and processing and the US ...
Eshar D - - 2012
Objectives: To determine urine specific gravity values in clinically healthy pet ferrets and explore possible associations with sex, sampling techniques, hydration status and urine analytes. Methods: Sixty-nine entire ferrets of both sexes, under one year of age, were included in this study. Physical examination, complete blood count, blood biochemistry, urine ...
Shaw Christiana M - - 2012
Novel drugs to inhibit insulin receptor substrate (IRS) and focal adhesion kinase (FAK) pathways are emerging and will be sarcoma subtype-specific. As a result, defining expression of proteins in these pathways; in select tumors is important in order to formulate therapeutic approaches to malignant peripheral nerve sheath tumors (MPNSTs). Fifty-three ...
Acosta-Pérez Gabriel - - 2012
OBJETIVE: To estimate the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in clinical isolates and to compare different methods for detection of MRSA in a lab with limited available personnel and resources. 140 Staphylococcus aureus strains isolated from patients in several departments were assayed for β-lactamase production, MIC-Vitek 2 oxacillin, ChromID ...
Rezania Kourosh - - 2012
Respiratory failure could result from a cardiopulmonary or a primary neurological disease. The latter could happen as a result of involvement of the central nervous system or a neuromuscular disease. Different neuromuscular diseases could result in respiratory failure by causing significant weakness of the respiratory and upper airways muscles. When ...
Pontes Thaís de Carvalho - - 2012
Fibromuscular dysplasia (FMD) involves small- and medium-sized arteries, being a well-known cause of hypertension in young Caucasian women, when renal arteries are involved. The etiology of FMD remains unknown, despite many theories. A genetic component is suspected to exist, because the pathology affects primarily Caucasians. Association between FMD and the ...
Mertlíková-Kaiserová Helena - - 2012
9-[2-(phosphonomethoxy)ethyl] guanine (PMEG) is a nucleotide analogue with anticancer activity. Here we investigate the role of ERK, p38, JNK and AKT kinases in PMEG-induced apoptosis. CCRF-CEM and HL-60 leukemia cells were used to assess MAPK mRNA and protein expression in PMEG-treated cells. MAPK activation was measured using phospho-specific antibodies. Apoptosis ...
Venton Geoffroy - - 2012
Despite great improvements in the management of metastatic clear cell renal carcinoma, complete responses with antiangiogenic therapies are infrequent and complete pathological responses remain anecdotal. We report the complete pathological response of a solitary bone metastasis from a clear cell renal carcinoma after sequential treatment with sunitinib and radiotherapy. In ...
Vernooij Meike W - - 2012
The role of structural neuroimaging in the diagnosis of Alzheimer's disease (AD) is becoming increasingly important. As a consequence, a basic understanding of what are normal brain changes in aging is key to be able to recognize what is abnormal. The first part of this article discusses normal versus pathologic ...
Waters James M - - 2012
Single primer amplification is shown to yield a DNA profile that is reproducible when based on the sequence content of the amplicons rather than on the pattern of length polymorphism. The sequence-based profile increases in reliability with increasing numbers of cycles of amplification. This process uses an arbitrarily chosen primer ...
Pepper Jon-Paul - - 2012
Postoperative psychosocial distress is a critical aspect of surgery, particularly in aesthetically sensitive areas. In this study, the authors assess the level of psychosocial distress associated with nasal reconstruction. The authors also compare postoperative distress levels associated with different reconstructive techniques throughout the healing process. The authors conducted a prospective ...
Seth Akhil K - - 2012
: Bacterial biofilm is recognized as a major detriment to wound healing. The efficacy of traditional wound care against biofilm has never been studied. The authors evaluated the effect of clinical strategies against biofilm-infected wounds in a quantitative, in vivo model. : Using a rabbit ear biofilm model, wounds were ...
Müntener C R - - 2012
In 2010, we observed again an increase in the number of declarations reported to the vigilance system for veterinary medicinal products up to a total of 160. The species and drug classes reported remained the same as in previous years: the majority of adverse drug reactions (ADRs) concerned either dogs ...
Ceccaroni Marcello - - 2012
Aim: To analyze pelvic dysfunctions, quality of life, and survival after nerve-sparing radical hysterectomy (NSRH) compared to classical radical hysterectomy (RH) for cervical cancer. All cervical cancer patients undergoing a RH or a NSRH were evaluated for pelvic dysfunctions and filled in a quality-of-life questionnaire. A total of 56 women ...
Mills Bruce - - 2012
This article explores emblematic examples of autistic ways of processing the world and effective practices for pediatrician interactions with children on the spectrum. It offers a parent perspective in relation to this dynamic, considering personal anecdotes that reflect on the communication, social, and sensory challenges for those with autism.
Wang Haojie - - 2012
Left ventricular (LV) mechanical dyssynchrony is an important prognostic marker for higher morbidity and mortality in patients with symptomatic heart failure. However, the response rate to resynchronization varies among patients meeting current guidelines for Cardiac resynchronization therapy (CRT). Two-dimensional echocardiography and Doppler-based techniques have shown variable results in the assessment ...
Rojas-Martínez Rosalba - - 2012
To describe the number of Mexican adults with undiagnosed diabetes and arterial hypertension and their association with obesity. The study included a sub-sample of 6 613 subjects aged 20 years or more who participated in the 2006 National Health and Nutrition Survey (ENSANUT 2006). Subjects with a previous diagnosis of ...
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