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Results 451 - 500 of 2476
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Heckmann Lotta - - 2012
Ecology Letters (2012) ABSTRACT: Body-size structure of food webs and adaptive foraging of consumers are two of the dominant concepts of our understanding how natural ecosystems maintain their stability and diversity. The interplay of these two processes, however, is a critically important yet unresolved issue. To fill this gap in ...
Szommer Tamás - - 2012
An efficient and convenient solution-phase synthesis of a 1H-1,2,4-triazole library with potential agrochemical activity is reported employing microwave-assisted organic synthesis (MAOS) and continuous-flow microfluidic synthetic methods starting from commercially available 3,5-dibromo-1H-1,2,4-triazole (1). MAOS was used for the synthesis of 5-amino-3-bromo-1,2,4-triazole analogs 3 and for their 3-aryl derivatives 4 via Suzuki-Miyaura ...
Hu Xiaogang X Department of Kinesiology, The Pennsylvania State University, University Park, PA 16802, USA. - - 2012
This study examined the influence of time gain on the visual-motor control of isometric force. Time gain denotes the spatial length on the computer screen representing the unit of elapsed time of the force output, through which the time properties of the visually perceived force output can be compressed or ...
Onoda Masashige - - 2012
The crystal structure, the electron configurations of V ions and the spin dynamics for the Li(9)V(3)P(8-δ)O(29-δ') insertion electrode system that exhibits a multiple-electron reaction are explored through measurements of x-ray four-circle diffraction, magnetization and nuclear magnetic resonance. The structure for the stoichiometric composition with δ = δ' = 0 is refined precisely and the ...
Sirichanchuen Buntitabhon - - 2012
Cisplatin-based chemotherapy frequently resulted in acquired resistance of cancer cells. The underlying mechanism of such resistance is not fully understood especially the involvement of autophagy and autophagic cell death. This study thus investigated whether an alteration in autophagy could be responsible for cisplatin resistance in the long-term exposure lung carcinoma ...
Trenfield Melanie A - - 2012
The influence of dissolved organic carbon (DOC), in the form of Suwannee River fulvic acid (SRFA), on uranium (U) toxicity to the unicellular eukaryote, Euglena gracilis (Z strain), was investigated at pH 6. In a background medium without SRFA, exposure of E. gracilis to 57 μg L(-1) U resulted in a 50% reduction in ...
Kumar Ambrish - - 2012
Acyl carrier protein (ACP) is a small acidic protein, an important cofactor involved in fatty acid biosynthesis. Its main function is to protect the growing acyl chain from the hydrophilic environment during fatty acid biosynthesis and simultaneously, present it to the active site of fatty acid pathway enzymes, liable for ...
Kobayashi Takashi - - 2012
There is as yet no optimal treatment regimen for patients with epidermal growth factor receptor (EGFR) gene wild-type non-small-cell lung cancer (NSCLC) that has progressed despite cytotoxic chemotherapy. This trial was performed to evaluate the efficacy and toxicity of erlotinib, a tyrosine kinase inhibitor of EGFR, in Japanese patients with ...
Shabbir Arsalan Q - - 2012
  Branchial cleft anomalies are rare developmental defects of the neck, with an estimated 2% to 3% being bilateral. Although most are isolated findings, some are associated with syndromes. We report a 2-month-old boy with bilateral branchial cleft anomalies, low-set ears, and hydronephrosis who tested positive for a mutation in ...
Khan S K - - 2012
We report a case of a 30-year old male, who presented with a right distal radius intra-articular fracture complicated by compartment syndrome. He was treated with fasciotomies and fracture fixation with a 3.5 mm LCP (Synthes(™)), followed 7 days later by skin graft. Repeat radiographs 8 weeks later showed a break across the ...
Ding Q L - - 2012
Summary.  Haemophilia A (HA) is the most common hereditary bleeding disorder caused by F8 gene mutation. Linkage analysis is an auxiliary strategy to direct mutation analysis for genetic counselling of HA. Here we characterize and validate a novel panel of six short tandem repeat (STR) loci for genetic counselling in ...
Nishikawa Kazuhiro - - 2012
BACKGROUND: The purpose of this study was twofold: (1) to compare S-1 with infusional 5-fluorouracil (FU) to determine which would be a better partner of paclitaxel (PTX), and (2) to compare a concurrent strategy with a sequential one, the latter strategy being the one that is widely used in Japanese ...
Rivera A - - 2012
Systematic data on the effect of irradiation with swift ions (Zn at 735 MeV and Xe at 929 MeV) on NaCl single crystals have been analysed in terms of a synergetic two-spike approach (thermal and excitation spikes). The coupling of the two spikes, simultaneously generated by the irradiation, contributes to the operation ...
Bedimo R - - 2012
OBJECTIVES: The aim of the study was to determine the prognostic value of HIV replication capacity (RC) for subsequent antiretroviral (ARV) treatment response in ARV-experienced patients. METHODS: RC and phenotypic resistance testing were performed at baseline and week 12 on plasma samples from patients randomized to undergo a 12-week ARV ...
Lipscomb Joseph - - 2012
Recent breast cancer treatment studies conducted in large urban settings have reported racial disparities in the appropriate use of adjuvant chemotherapy. This article presents the first focused evaluation of black-white differences in receipt and completion of chemotherapy for breast cancer in a primarily rural region of the United States. We ...
Zafar Mazhar Iqbal - - 2012
This paper evaluates the effects of different time-varying exposure patterns of the strobilurin fungicide azoxystrobin on freshwater microsocosm communities. These exposure patterns included two treatments with a similar peak but different time-weighted average (TWA) concentrations, and two treatments with similar TWA but different peak concentrations. The experiment was carried out ...
Jiang Xiu-Mei - - 2012
Gold nanomaterials (Au NMs) have attracted increasing attention in biomedicine due to their facile preparation, multifunctional modifications, unique optical and electrical properties, and good biocompatibility. The physicochemical properties of Au NMs at nanoscale, like size, shape, surface chemistry, and near field effects, are rendering Au NMs potent candidates in biomedicine. ...
Diamond Lisa M - - 2012
Over the past decade, numerous studies have documented fundamental differences between the phenomenology of male and female sexual orientation, largely centering on women's capacity for fluidity in their sexual attractions. The past decade has also witnessed fundamental changes in clinical perspectives on "normal" versus "dysfunctional" patterns of female sexual desire, ...
Lee Jaebum - - 2012
BACKGROUND: Implant dentistry in the posterior maxilla often requires bone augmentation. The gold standard, autogenous bone graft, requires additional surgery with associated morbidity, while bone biomaterials may not support relevant bone formation. Recombinant human bone morphogenetic protein-2 (rhBMP-2) in an absorbable collagen sponge (ACS), however, induces significant, clinically relevant bone ...
Kjaer Line - - 2012
  Hereditary angioedema (HAE) is a rare inherited disease that is often difficult to diagnose. We report a case of a 9-year-old boy with a spontaneous mutation causing HAE, diagnosed after a life-threatening episode of angioedema of the head and upper respiratory tract after a 5-year history of recurrent skin ...
Vávrová Jiƙina - - 2012
In the work presented here, changes in haematopoiesis of mice (B6129SF2/J) were studied 1 year after their whole-body exposure to a dose of 7 Gy (72% of mice survived). The irradiated mice were compared with non-irradiated younger (4 months of age) and older (16 months of age) mice. There was a significant increase in ...
Liu Keshao - - 2012
The alphaproteobacterial strain JLT2003(T) was isolated from surface seawater off the coast of Guishan island, Taiwan. The strain was Gram negative, ovoid or coccoid, non-motile and formed pink colonies on marine agar 2216 (MA; DIFCO) medium. The dominant fatty acids were C(18:1)ω7c, cyclo C(19:0)ω8c, and C(16:0). The polar lipid profile ...
Balzano Sergio - - 2012
The composition of photosynthetic pico and nanoeukaryotes was investigated in the North East Pacific and the Arctic Ocean with special emphasis on the Beaufort Sea during the MALINA cruise in summer 2009. Photosynthetic populations were sorted using flow cytometry based on their size and pigment fluorescence. Diversity of the sorted ...
Mattar C N - - 2012
Correction of perinatally lethal neurogenetic diseases requires efficient transduction of several cell types within the relatively inaccessible CNS. Intravenous AAV9 delivery in mouse has achieved development stage-specific transduction of neuronal cell types, with superior neuron-targeting efficiency demonstrated in prenatal compared with postnatal recipients. Because of the clinical relevance of the ...
Hu C D - - 2012
The Dzyaloshinskii-Moriya (DM) interaction in metals is an important mechanism for many magnetic properties. We start with the s-d exchange model and spin-orbit interaction for weak itinerant ferromagnetic systems to establish the form of DM interaction for metallic magnetic systems. The s-d exchange interaction is treated accurately and the conduction ...
Marentette Julie R - - 2012
Changes in animal movement (frequency or speed of locomotion) following exposure to a toxicant are frequently considered a biomarker of contaminant exposure and are some of the most widely reported behavioral results in toxicological literature. However, the ecological consequences of such behavioral changes, such as effects on toxicant transfer in ...
Bernal Ashley - - 2012
A new nano-manufacturing method for the creation of high aspect-ratio ferroelectric (PZT) nanostructures by use of polymeric templates is presented. The ferroelectric response is characterized by band-excitation PFM, supporting the high quality of the nanostructures. Piezoelectric size effects for ferroelectric materials are reported for the first time in nanotube configuration ...
Lecoq L - - 2012
The D: ,D: -transpeptidase activity of Penicillin Binding Proteins (PBPs) is essential to maintain cell wall integrity. PBPs catalyze the final step of the peptidoglycan synthesis by forming 4 → 3 cross-links between two peptide stems. Recently, a novel β-lactam resistance mechanism involving L: ,D: -transpeptidases has been identified in Enterococcus faecium ...
Schaaf Pierre - - 2012
The alternate deposition of polyanions and polycations on a solid substrate leads to the formation of nanometer to micrometer films called Polyelectrolyte Multilayers. This step-by-step construction of organic films constitutes a method of choice to functionalize surfaces with applications ranging from optical to bioactive coatings. The method was originally developed ...
Bartlett Michael D - - 2012
Hand-sized gecko-inspired adhesives with reversible force capacities as high as 2950 N (29.5 N cm(-2) ) are designed without the use of fibrillar features through a simple scaling theory. The scaling theory describes both natural and synthetic gecko-inspired adhesives, over 14 orders of magnitude in adhesive force capacity, from nanoscopic ...
Relihan E C - - 2012
BACKGROUND: Medication error reporting systems in hospitals are faced with the challenge of processing vast numbers of reports which identify a myriad of safety issues. With such large volumes of data and limited resources it makes sense to adopt a prioritisation approach. Several published studies have focused solely on the ...
Alghamdi Hamdan S - - 2012
OBJECTIVE: The current study aimed to evaluate the osteogenic potential of electrosprayed organic and non-organic surface coatings in a gap-implant model over 4 and 12 weeks of implantation into the dog mandible. MATERIAL AND METHODS: Sixteen Beagle dogs received experimental titanium implants in the mandible 3 months after removal of left premolars ...
Li Haiqing - - 2012
Multipyrene terminated hyperbranched polyglycidol (mPHP) has been synthesized and used to non-covalently functionalize pristine graphene sheets (GSs) through π-π stacking interactions. Mediated by the mPHP layer, a variety of metal nanoparticles (Au, Ag and Pt) were in situ generated and deposited onto the surface-modified GS, yielding versatile GS/mPHP/metal nanohybrids. As ...
Huang Y - - 2012
Depending on the environment, dendritic cells (DCs) may become active or tolerogenic, but little is known about whether heritable epigenetic modifications are involved in these processes. Here, we have found that epigenetic histone modifications can regulate the differentiation of human monocyte-derived DCs (moDCs) into either activated or tolerized DCs. The ...
Pan Qiong - - 2012
We report a novel on-line electrophoretic sample clean-up approach for highly sensitive and reproducible microchip electrophoretic (μCE) immunoassay of low-abundance proteins in human serum. The method takes advantage of the differential effect of field-amplified sample stacking on molecules with different electrophoretic mobility. Large interfering proteins are removed from the loading ...
Sung Shih-Hsien - - 2012
BackgroundCentral systolic blood pressure (SBP) can be estimated by an oscillometric method developed from a pulse volume plethysmography (PVP) device. The present study applied this novel method to a noninvasive blood pressure monitor (NBPM).MethodsWe enrolled 50 patients (37 men, age range 30-84 years) referred for cardiac catheterization. Invasive right brachial ...
Ogihara Toshio - - 2012
The Combination Therapy of Hypertension to Prevent Cardiovascular Events (COPE) trial demonstrated that the calcium-channel blocker benidipine-based combination therapies with an angiotensin-receptor blocker (ARB), a β-blocker, or a thiazide diuretic (thiazide) were similarly effective in preventing cardiovascular events and achieving the target blood pressure (BP; <140/90 mm Hg). We further evaluated the ...
Salinas Pablo - - 2012
To study a cohort of consecutive patients undergoing transcatheter aortic valve implantation (TAVI) and compare the outcomes of atrial fibrillation (AF) patients vs patients in sinus rhythm (SR). All consecutive patients undergoing TAVI in our hospital were included. The AF group comprised patients in AF at the time of TAVI ...
Singh Avinash - - 2012
The onset and melting of locally staggered charge/orbital correlations is investigated within a two-orbital correlated electron model with inter-orbital and inter-site Coulomb interactions. The CE-type orbital correlation exhibits a sharp onset close to the Curie temperature and rapid thermal melting thereafter, which provides quantitative understanding of the (π/2,π/2,0) feature observed ...
Hyggen Christer - - 2012
Aims:  The study aimed at examining the associations between cannabis use and work commitment. Design:  We used a 25 year panel survey initiated in 1985 with follow-ups in 1987, 1989, 1993, 2003 and 2010. Registered data from a range of public registers were matched with individual responses for the entire ...
Aldrighetti Luca - - 2012
BACKGROUND: Laparoscopy is considered the "gold standard" to perform left-lateral sectionectomy with results identical to those of open surgery, yielding decreased postoperative pain and disability, reduced hospital stay, and shortened patient recovery time. As the emphasis on minimizing the invasiveness of surgical techniques continues, laparoendoscopic single site (LESS) surgery is ...
Xiong Caiqiao - - 2012
In this article, the charge detection quadrupole mass spectrometry (CD-ITMS) driven by rectangular and triangular waveforms (rect-CD-ITMS and tri-CD-ITMS) was developed for the characterization of microparticles. Since the frequency scan of rectangular and triangular waveform could be realized easier than that of sinusoidal waveform, this research intends to provide simpler ...
Leonhartsberger Nicolai - - 2012
Patients with metastatic renal cell carcinoma (RCC) undergoing cytokine or targeted therapies may show a remarkable decline in quality of life (QoL). We wanted to evaluate QoL in patients with metastatic RCC undergoing therapeutic vaccination with dendritic cells (DCs). In a cross-sectional analysis, QoL was therefore assessed in RCC patients ...
Ohyama Bungo - - 2012
Epitope spreading is involved in inducing and maintaining self-reactivity. Epitope spreading in pemphigus vulgaris (PV), caused by IgG autoantibodies to desmoglein 3 (Dsg3) and Dsg1, was previously analyzed using Dsg3/Dsg1 extracellular domain-swapped molecules. However, precise identification of the responsible epitopes in each molecule by using only this method was problematic. ...
Yamauchi Kensuke - - 2012
OBJECTIVES: The aim of the present study was to present the results of patients followed for at least 3 years who underwent horizontal distraction osteogenesis DO and a final implant prosthesis. MATERIAL AND METHODS: A total of 13 sites in 12 patients (three men, nine women; mean age 45.4 years, range 21-63 years) ...
Prindaville Brea - - 2012
  Microgeodic disease, similar to chilblains (pernio), is characterized by painful, erythematous swelling, as well as small, punched-out erosions found in affected phalanges. Although they share a similar appearance and proposed pathogenesis, chilblains has rarely been diagnosed in children with microgeodic disease, and in those cases has not been confirmed ...
Whitehouse Andrew J O - - 2012
Background:  Preliminary evidence suggests that prenatal testosterone exposure may be associated with language delay. However, no study has examined a large sample of children at multiple time-points. Methods:  Umbilical cord blood samples were obtained at 861 births and analysed for bioavailable testosterone (BioT) concentrations. When participating offspring were 1, 2 ...
Weaver Laurel - - 2012
In this review, we discuss the treatment of anorexia nervosa (AN) in children and adolescents, highlighting inpatient and outpatient psychiatric treatment. AN is an illness that involves medical and psychological issues; hence, treatment often requires the seamless integration of several medical professionals. It is important that the treatment model be ...
Urso E - - 2012
The reported incidence of hereditary colorectal cancers (CRCs) is widely variable. The principal aim of the study was to prospectively evaluate the incidence of familial CRCs in a region of northern Italy using a standardized method. Consecutive CRC patients were prospectively enrolled from October 2002 to December 2003. Patients underwent ...
Amis Andrew A - - 2012
This paper reviews the functional anatomy of the anterior cruciate ligament (ACL), which has a parallel array of collagen fascicles that have usually been divided into two 'fibre bundles': anteromedial (AM) and posterolateral (PL), according to their tibial attachment sites. The PL bundle has shorter fibres, and so it is ...
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