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Minamino Tohru - - 2012
FlgN chaperone acts as a bodyguard to protect its cognate substrates, FlgK and FlgL, from proteolysis in the cytoplasm. Docking of the FlgN-FlgK complex with the FliI ATPase of the flagellar type III export apparatus is key to the protein export process. However, a ΔfliH-fliI flhB(P28T) mutant forms some flagella ...
Carin-Levy G - - 2012
Delirium is a common complication in acute stroke yet there is uncertainty regarding how best to screen for and diagnose delirium after stroke. We sought to establish how delirium after stroke is identified, its incidence rates and factors predicting its development. We conducted a systematic review of studies investigating delirium ...
Coulson C J - - 2012
Aim:(1) To assess hypersensitivity to bismuth iodoform paraffin paste impregnated ribbon gauze following its use in packing canal wall down mastoidectomy cavities; (2) to determine if isolation of the skin and mucosa from the pack, using thin Silastic sheeting and Cortisporin ointment, reduces hypersensitivity reactions, compared with a previous series; ...
Malki Manar - - 2012
• To establish whether it is safe to manage minimally symptomatic and asymptomatic pelvi-ureteric junction obstruction (PUJO) conservatively. • In all, 50 patients with PUJO diagnosed with dynamic renography, and monitored with at least two renograms. • In all, 19 patients were totally asymptomatic, while 31 patients had minimal symptoms ...
Sander Suzanne - - 2012
Cytoplasmic proteins that affect integrin diffusion in the cell membrane are identified using a combination of fluorescence recovery after photobleaching (FRAP) and RNA interference. Integrin receptors are essential for many cellular events, and alterations in lateral diffusion are one mechanism for modulating their function. In cells expressing native cytoplasmic protein ...
Pennesi Marco - - 2012
BACKGROUND: Recent guidelines on urinary tract infection (UTI) agree on reducing the number of invasive procedures. None of these has been validated by a long-term study. We describe our 11-years experience in the application of a diagnostic protocol that uses a reduced number of invasive procedures. METHODS: We reviewed retrospectively ...
Woodhead C - - 2012
BACKGROUND: Interest in the mental health of women deployed to modern military campaigns is increasing, although research examining gender differences is limited. Little is known about experiences women have had on these deployments, or whether men and women respond differently to combat exposure.MethodThe current study used data from a representative ...
Niisato Emi - - 2012
Collapsin response mediator proteins (CRMPs) are a family of cytosolic phosphoproteins that consist of 5 members (CRMP 1-5). CRMP2 and CRMP4 regulate neurite outgrowth by binding to tubulin heterodimers, resulting in the assembly of microtubules. CRMP2 also mediates the growth cone collapse response to the repulsive guidance molecule semaphorin-3A (Sema3A). ...
Mounfield William P WP - - 2012
Uniform matrix deposition on tissue samples for matrix-assisted laser desorption/ionization (MALDI) is key for reproducible analyte ion signals. Current methods often result in nonhomogenous matrix deposition, and take time and effort to produce acceptable ion signals. Here we describe a fully-automated method for matrix deposition using an enclosed spray chamber ...
Guzmán-Murillo María A - - 2012
We evaluated the salt tolerance of hybrids of pepper (Capsicum annuum L.) during germination. Treatments were applied at 0, 25, and 50 mM NaCl with preparations of supplemental extracts of the microalgae Dunaliella salina and Phaeodactylum tricornutum to determine the percentage germination rate as well as measured indicators of oxidative stress ...
Lauridsen Eva - - 2012
Abstract -  Aim: To analyze the influence of a crown fracture without pulp exposure on the risk of pulp necrosis (PN) in teeth with extrusion or lateral luxation. Material and methods: The study included 82 permanent incisors with extrusion from 78 patients (57 male, 21 female) and 179 permanent incisors with lateral ...
Hung Albert M - - 2012
Large-area films of vertically-aligned semiconductor nanorods have the potential to be useful, active materials for optoelectronic devices. We demonstrate here a highly facile thermal annealing approach for reversibly assembling 28 nm long CdSe nanorods into vertically aligned arrays in solution. Using temperature to control solvent strength, aggregated nanorods in a ...
Steiner Eric T - - 2012
Because of wide disparities in college students' math knowledge-that is, their math achievement-studies of cognitive processing in math tasks also need to assess their individual level of math achievement. For many research settings, however, using existing math achievement tests is either too costly or too time consuming. To solve this ...
Ishida Naoki - - 2012
The rhodium-catalysed reaction of 1-(2-haloaryl)cyclobutanols afforded 3,3-disubstituted α-tetralones. The reaction was applied to the asymmetric synthesis of α-tetralones bearing a chiral quaternary carbon centre at the 3-position, which was otherwise difficult to execute.
Lim Michael - - 2012
BACKGROUND: The restoration of intestinal continuity after open abdominal surgery can be technically challenging. The authors describe their experience with the laparoscopic approach to attempted reversal for patients with an exteriorized intestine. METHODS: A consecutive series of patients under the care of a single surgeon (D.B.) underwent laparoscopic restoration of ...
Huang Peng - - 2012
A convenient and efficient synthesis of substituted 2,3-dihydrothieno[3,2-c]pyridin-4(5H)-ones has been developed and relies upon a domino reaction of dimethylaminopropenoyl cyclopropanes initiated by Lawesson's reagent. A mechanism involving regioselective thionation, ring-enlargement, and an intramolecular aza-cyclization sequence is proposed. This protocol was utilized as a one-pot route to thieno[3,2-c]pyridin-4(5H)-ones with DDQ as ...
Tan Xiuwen - - 2012
The purpose of our study was to investigate the feasibility of using less-concentrated cryoprotectants supplemented with ice blocker Supercool X-1000 to vitrify ovarian tissues. Mouse ovaries were cryopreserved in different concentrations of vitrification solution alone or with Supercool X-1000, and fresh non-frozen ovaries were used as control. The proportions of ...
Kiesslich Tobias - - 2012
The Hedgehog (Hh) pathway is one of the central developmental signaling mechanisms, which have recently been shown to contribute to malignant progression of a variety of human cancers. Additionally, the role of Hh and other embryonic signaling pathways in the regulation and maintenance of the tumorigenic cancer stem / -initiating ...
Koirala Deepak - - 2012
Intramolecular folding in three tandem guanine repeats of human telomeric DNA has been investigated using optical-tweezers, MD simulation and circular dichroism. A mechanically and thermodynamically stable species in this sequence shows a structure consistent with a triplex conformation. A similar species has also been observed to coexist with a G-quadruplex ...
Bouck E C - - 2012
Background  A conversation currently exists regarding secondary curriculum (e.g. academics, functional) for students with moderate/severe intellectual disability (ID) without a large research base connecting curriculum to outcomes. Method  This study represented a secondary analysis of the National Longitudinal Transition Study-2 (NLTS2) data to understand in-school curriculum and educational programming for ...
Ann Praestmark Juul Kezia - - 2012
BACKGROUND: Thinner and shorter needles for subcutaneous administration are continuously developed. Previous studies have shown that a thinner needle causes fewer occurrences of painful needle insertions and that a shorter needle decreases the occurrence of painful intramuscular injections. However, little is known about local drug delivery in relation to needle ...
Fede G - - 2012
In patients with cirrhosis adrenal insufficiency (AI) is reported during sepsis and septic shock, and is associated with increased mortality. Consequently, the term "hepato-adrenal syndrome" was proposed. Some studies have shown that AI is frequent in stable cirrhosis, and in cirrhosis associated with decompensation other than sepsis, such as bleeding ...
Hauge Solveig - - 2012
Scand J Caring Sci; 2012 Variations in older persons' descriptions of the burden of loneliness Research indicates that approximately one-third of older people over the age of 65 years report loneliness, with even higher rates among those aged over 85. Loneliness is associated with a variety of health issues, such as ...
Zummo F P - - 2012
Most enzymes involved in tryptophan catabolism via kynurenine formation are highly conserved in Prokaryotes and Eukaryotes. In humans, alterations of this pathway have been related to different pathologies mainly involving the central nervous system. In Bacteria, tryptophan and some of its derivates are important antibiotic precursors. Tryptophan degradation via kynurenine ...
Lysaght Rosemary - - 2012
Purpose: This paper presents the results of a scoping review of the research literature on community-based employment for individuals with intellectual disabilities from 2000 to 2010. The review examined the variables studied in each paper, and considered the degree to which elements of social inclusion were addressed. Method: The search ...
Maffeis C - - 2012
Background and Aims:Skipping breakfast influences cognitive performance. The aim of our study was to investigate the relationship between the variation of hormonal and metabolic postprandial parameters induced by breakfast consumption or fasting and cognitive performance in obese children.Methods:Cross-sectional study for repeated measures. Memory and attention assessment tests, hormones and nutrient ...
Springer Anne - - 2012
Processing of action words has been shown to influence the perception of the actions the words refer to. Specifically, the accuracy with which people predict the future course of actions observed in another individual seems to be affected by verbal primes. Two processes may be involved in action prediction; dynamic ...
Gough Clare E - - 2012
We compared changes in performance and total haemoglobin mass (tHb) of elite swimmers in the weeks following either Classic or Live High:Train Low (LHTL) altitude training. Twenty-six elite swimmers (15 male, 11 female, 21.4 ± 2.7 years; mean ± SD) were divided into two groups for 3 weeks of either Classic or LHTL altitude training. Swimming ...
Badea Ovidiu - - 2012
Air pollution, bulk precipitation, throughfall, soil condition, foliar nutrients, as well as forest health and growth were studied in 2006-2009 in a long-term ecological research (LTER) network in the Bucegi Mountains, Romania. Ozone (O(3)) was high indicating a potential for phytotoxicity. Ammonia (NH(3)) concentrations rose to levels that could contribute ...
Kukaswadia Atif - - 2012
OBJECTIVES: Although evidence links increased adiposity status with bullying involvement, it is unknown whether this leads to behaviors such as weapon carrying. The purpose of this study was to: (1) analyze relationships between adiposity status and risks for weapon carrying among Canadian school children, and (2) whether this relationship was ...
Kinshuck A J - - 2012
Objectives:We examined the accuracy of magnetic resonance imaging in assessing thyroid cartilage and thyroid gland invasion in patients undergoing total laryngectomy for squamous cell carcinoma, by comparing histopathology results with imaging findings.Study design:A retrospective study reviewed histology and magnetic resonance scan results for all total laryngectomies performed between 1998-2008 at ...
Lifa Tulip - - 2012
Desferrioxamine B (DFOB) was biotinylated at the pendant amine using solid-phase organic synthesis (SPOS) on a matrix used conventionally for metal affinity chromatography. The strength of the DFOB-matrix coordinate bonds was functionally equivalent to a covalent bond which underpinned the veracity of the SPOS format. After washing excess reagents, biotin-DFOB ...
Matsumoto T - - 2012
Acquired haemophilia A (AHA) is caused by the development of factor (F)VIII autoantibodies, demonstrating type 1 or type 2 inhibitory behaviour, and results in more serious haemorrhagic symptoms than in congenital severe HA. The reason(s) for this remains unknown, however. The global coagulation assays, thrombin generation tests and clot waveform ...
Gremmel Thomas - - 2012
BACKGROUND: The frequency of heparin-induced platelet antibodies (H/PF4 antibodies) following heparin exposure during percutaneous intervention with stent implantation is unknown. These antibodies may activate platelets and therefore contribute to high on-clopidogrel residual platelet reactivity (HRPR). METHODS: We screened 288 patients after angioplasty and stenting for H/PF4 antibodies by an IgG/A/M ...
Pasek Jarosław - - 2012
Chronic venous insufficiency, as well as crural vein ulceration, developing at its background, poses a serious clinical problem. Treatment is costly and lengthy. Intense development of physical medicine allows to reduce the time of treatment, as well as to improve the life quality in numerous soft tissue ailments, including wounds ...
Friedlander Justin I - - 2012
What's known on the subject? and What does the study add? Nearly 90% of patients with interstitial cystitis/bladder pain syndrome (IC/BPS) report sensitivities to a wide variety of dietary comestibles. Current questionnaire-based literature suggests that citrus fruits, tomatoes, vitamin C, artificial sweeteners, coffee, tea, carbonated and alcoholic beverages, and spicy ...
Takei Hiroyuki - - 2012
Health-related quality of life (HRQOL), symptoms of depression, and adverse events (AEs) were compared between Japanese postmenopausal patients with hormone-sensitive breast cancer (BC) who received adjuvant tamoxifen, exemestane, or anastrozole in an open-labeled, randomized, multicenter trial designated as the National Surgical Adjuvant Study of Breast Cancer (N-SAS BC) 04 substudy ...
Chen Xiu-Min - - 2012
A glucose-lysine (Glu-Lys) Maillard reaction mixture heated at 121°C for 60 min was processed by ultrafiltration, ethyl acetate extraction, and semi-preparative HPLC to recover a bioactive fraction, termed F3. F3, characterized by spectral analysis to contain three distinct components, inhibited NO and IL-8 by 70 and 61%, respectively, at a ...
Libório Alexandre Braga - - 2012
BACKGROUND: Renal complications in acromegaly include glomerular hyperfiltration, insulin resistance, hypercalciuria and urolithiasis. The aim of this study was to investigate whether urinary calcium (U(Ca)) excretion is a direct consequence of growth hormone secretion or secondary to hyperfiltration and/or insulin resistance. METHODS: We performed a cross-sectional study of 58 patients ...
Dhakras Dipti - - 2012
PVDF nanofibers are prepared using electrospinning. The effect of addition of a hydrated salt, nickel chloride hexahydrate (NiCl(2)·6H(2)O), on the phase formation is examined. Addition of the hydrated salt (NC) is found to enhance the polar β phase by about 30%. The peak to peak piezo-voltage generated for PVDF NC ...
Papadia Marina - - 2012
Our purpose was to examine toxoplasmic serology in relation to episodes of suspected acute toxoplasmic retinochoroiditis and evaluate its use in the appraisal of patients. The mean values of enzymatic immunoassay (EIA) titers for toxoplasmic antibodies were retrospectively compared in patients with active and inactive toxoplasmosis and in a third ...
Tokuno Craig D - - 2012
The purpose of this study was to examine whether passively rotating the knee would result in parallel or differential changes to the medial gastrocnemius (MG) and soleus (SOL) H-reflex amplitudes. Since passive knee rotation alters the muscle length of the MG, but not the SOL, it was hypothesized that the ...
Kuwazuru Osamu - - 2012
BACKGROUND/PURPOSE: Does the morphology of wrinkles alter gradually with aging or suddenly at a certain age? On the basis of the theoretic wrinkle simulation of ideal skin, we have suggested that the wrinkle morphology suddenly changes from stratum corneum wrinkling to epidermis wrinkling; the former induces shallow fine furrows, and ...
Fishelson Lev - - 2012
The present study describes the distribution of taste buds and teeth in the oropharyngeal cavity of 13 species of adult (18-60 mm SL) Starksiini fishes inhabiting subtidal waters of the Neotropical region. Four types of taste buds described previously in other fish groups were observed within the oropharyngeal cavity, of ...
Doherty Alison H - - 2012
Long periods of inactivity in most mammals result in bone loss that may not be completely recoverable during an individual's lifetime regardless of future activity. Prolonged inactivity is normal during hibernation, but it remains uncertain whether hibernating mammals suffer decreased bone properties after hibernation that affects survival. We test the ...
Nagashima Koichi - - 2012
BACKGROUND: The influence of inter-electrode spacing (IES) on complex fractionated atrial electrograms (CFAEs) and dominant frequency (DF) detection was assessed. METHODS: Bipolar electrograms were recorded via an octapolar catheter (2-mm electrode spacing) from left atrial CFAEs sites in 17 atrial fibrillation patients. The CFE-mean was calculated at IES of the ...
Moo E K - - 2012
Experimental findings indicate that in-situ chondrocytes die readily following impact loading, but remain essentially unaffected at low (non-impact) strain rates. This study was aimed at identifying possible causes for cell death in impact loading by quantifying chondrocyte mechanics when cartilage was subjected to a 5% nominal tissue strain at different ...
Neman J - - 2012
There is a pressing need for new therapeutics for the generation and transplantation of oligodendrocyte to the white matter to help replace and render injured cells that are lost in demyelinating disease. There are a few protocols describing a homogenous derivation of non-manipulated mouse embryonic stem cells to oligodendrocytes (ES-OL). ...
Iwata Daiju - - 2012
BACKGROUND: Infliximab, an anti-TNF-α monoclonal antibody, administered to Behçet's disease (BD) patients in Japan with refractory intraocular inflammation, has shown excellent clinical results. However, some patients demonstrate a decreased response to infliximab during the course of the treatment. In the present study, we investigated the correlation between this reduced therapeutic ...
De Sousa-Coelho Ana Luísa - - 2012
Nutrient deprivation or starvation frequently correlates with amino acid limitation. Amino acid starvation initiates a signal transduction cascade starting with the activation of the kinase GCN2 phosphorylation of eukaryotic initiation factor 2, global protein synthesis reduction and increased activating transcription factor (ATF) 4. ATF4 modulates a wide spectrum of genes ...
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