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Petukhova Alla - - 2012
Nanomaterials with vectoral electromagnetic properties have potential applications in solar cells, plasmonic cavity resonators, light polarizers, and biosensing. Here a new, simple, solution-based method for producing nanomaterials comprising vertically aligned standing arrays of gold nanorods (NRs) end-functionalized with polymer ligands is reported. The method utilizes the side-by-side assembly of the ...
Li Joel B - - 2012
Scanning Kelvin probe microscopy (SKPM) measurements reveal a higher positive surface potential at the grain boundaries (GBs) as compared to the grain while conductive atomic force microscopy (C-AFM) measurements show higher current flow in the vicinity of the GBs of Cu(2) ZnSnS(4) (CZTS) and Cu(2) ZnSn(S,Se)(4) (CZTSSe). These results demonstrate ...
Wong Linda L LL University of Hawaii Cancer Center, Honolulu, HI, USA. - - 2012
Hawaii has the highest incidence of hepatocellular cancer (HCC) in the United States and the largest proportion of Asians and Pacific Islanders. HCC studies generally combine these groups into 1 ethnicity, and we sought to examine differences between Asian and Pacific Islander subpopulations. Demographic, clinical, and treatment data for 617 ...
Wang Yue - - 2012
A preferred-handed helical conformation was induced to poly(9,9-dioctylfluoren-2,7-diyl) (PDOF) in a thin film form upon irradiation with single-handed circularly polarized light (CPL) where the induction was reversible.
Baudoux A-C AC Scripps Institution of Oceanography, Marine Biology Research Division, University of California San Diego, La Jolla, CA 92093, USA. - - 2012
We report on a genomic and functional analysis of a novel marine siphovirus, the Vibrio phage SIO-2. This phage is lytic for related Vibrio species of great ecological interest including the broadly antagonistic bacterium Vibrio sp. SWAT3 as well as notable members of the Harveyi clade (V.harveyi ATTC BAA-1116 and ...
Werts Martinus H V - - 2012
A simple and versatile methodology has been developed for the simultaneous measurement of multiple concentration profiles of colourants in transparent microfluidic systems, using a conventional transmitted light microscope, a digital colour (RGB) camera and numerical image processing combined with multicomponent analysis. Rigorous application of the Beer-Lambert law would require monochromatic ...
Joensson Haakan N - - 2012
We present a novel homogeneous ("mix-incubate-read") droplet microfluidic assay for specific protein detection in picoliter volumes by fluorescence polarization (FP), for the first time demonstrating the use of FP in a droplet microfluidic assay. Using an FP-based assay we detect streptavidin concentrations as low as 500 nM and demonstrate that an ...
Langeron A A Département de gynécologie-obstétrique et médecine de la reproduction, hôpital Nord, CHU de Saint-Étienne, avenue Albert-Raimond, Saint-Étienne, - - 2012
To evaluate risk factors associated with failed forceps delivery and to compare the maternal and neonatal morbidity. In this retrospective case-control study, all failed forceps delivery cases were analyzed from January 2005 to June 2008 and were compared to a successful forceps delivery cohort. The rate of failed forceps extraction ...
Jung Y-J - - 2012
Introduction:  The utility of WBC cell population data (CPD) for the differential diagnosis of viral infection from normal control, bacterial infection, and tuberculosis in children was investigated. Methods:  A data set of 602 total whole-blood samples were analyzed on the DxH 800 System for complete blood cell count (CBC) with ...
Wang Yi - - 2012
Zein, a major protein of corn, is rich in α-helical structure. It has an amphiphilic character and is capable of self-assembly. Zein can self-assemble into various mesostructures that may find applications in food, agricultural, and biomedical engineering. Understanding the mechanism of zein self-assembly at the nanoscale is important for further ...
De Witte Evy - - 2012
Variability of complement factor 3 (C3) mobility in serum protein electrophoresis was investigated. We found that the migration time of C3 can be reproducibly determined (beween-run CV=0.76%) using clinical capillary electrophoresis (CE) equipment (the Capillarys™ 2 system, Sebia). Moreover, we found a significant difference (p<0.001) in migration times of the ...
Dondi Ruggero R Department of Chemistry, University of Leicester, University Road, Leicester, LE1 1RE, - - 2012
A mild, facile one-step synthetic strategy for the preparation of size- and shape-controlled silver nanoparticles (AgNPs) is presented. The high degree of size- and shape-control of these AgNPs is achieved by the use of triazole sugar ligands scaffolded by a central resorcinol ether core. Both the triazoles and the resorcinol ...
Faber Helene - - 2012
Diclofenac is a frequently prescribed drug for rheumatic diseases and muscle pain. In rare cases, it may be associated with a severe hepatotoxicity. In literature, it is discussed whether this toxicity is related to the oxidative phase I metabolism, resulting in electrophilic quinone imines, which can subsequently react with nucleophiles ...
Masillo A A Department of Psychosis Studies, King's College London, King's Health Partners, Institute of Psychiatry, London, - - 2012
Interpersonal sensitivity is a personality trait described as excessive awareness of both the behaviour and feelings of others. Although interpersonal sensitivity has been found to be one of the vulnerability factors to depression, there has been little interest in its relationship with the prodromal phase of psychosis. The aims of ...
Fineberg Naomi A - - 2012
Pharmacological strategies for the treatment of obsessive-compulsive disorder (OCD) continue to develop apace but deficiencies remain. We present an updated literature review of the evidence supporting available strategies. We aim to answer key questions including: (1) What are the first-line treatments? (2) Does pharmacotherapy improve health-related quality of life? (3) ...
Solus Jason F - - 2012
To compare the success and complications of trabeculectomy performed with limbus-based and fornix-based conjunctival approaches. Retrospective case series with some prospective data collection. Consecutive patients undergoing trabeculectomy by 2 surgeons between May 2000 and October 2008. We performed limbus-based operations during the first 4 years and fornix-based operations during the ...
Deflorio Giuliana - - 2012
Metabolite fingerprinting of Sitka spruce (Picea sitchensis) bark and sapwood was carried out by (1)H nuclear magnetic resonance after wounding and artificial inoculation with the white rot fungus Heterobasidion annosum sensu stricto. The aim was to determine whether metabolites would differ in clones showing differing levels of susceptibility to H. ...
Anderson Brian J - - 2012
The pharmacokinetic (PK) parameters that are important for dosing (e.g., clearance and volume) are well known. They are used in universal mathematical formulae that describe the time course of drug concentration. Additional formulae can be used to describe major covariate effects in children, such as size and maturation. PK parameters ...
Li Ying - - 2012
In order to isolate and characterize novel angiotensin-I-converting enzyme (ACE) inhibitory peptide from loach (Misgurnus anguillicaudatus), six proteases of pepsin, -chymotrypsin, bromelain, papain, alcalase and neutrase, were used to hydrolyze loach protein. The hydrolysate (LPH) generated by bromelain (ratio of enzyme to substrate, 3:1000 (w/w)) was found to have the ...
Muhammed Maged M Harvard Medical School, Massachusetts General Hospital, Division of Infectious Diseases, Boston, MA, - - 2012
Fusariosis is an emerging infectious complication of immune deficiency, but models to study this infection are lacking. The use of the soil nematode Caenorhabditis elegans as a model host to study the pathogenesis of Fusarium spp. was investigated. We observed that Fusarium conidia consumed by C. elegans can cause a ...
Wyrwoll C S CS Endocrinology Unit, Centre for Cardiovascular Science, University of Edinburgh, Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, - - 2012
There is increasing evidence for a role for epigenetic modifications in early life 'programming' effects. Altered placental methyl donor transport may impact on the establishment of epigenetic marks in the fetus. This study investigated the effects of prenatal glucocorticoid overexposure on placental methyl donor transport. Glucocorticoids increased folate but decreased ...
Druzhinina Tamara S - - 2012
A reliable nanofabrication concept to engineer metallic nanometric gap structures and to incorporate silver nanoparticles within the gaps utilizing a combination of self-assembly strategies and electrochemical oxidation lithography is developed. The approach uses the differences in oxidation kinetics of n-octadecyltrichlorosilane (OTS) monolayer and bilayer structures. The processes are investigated in ...
Kucheyev S O - - 2012
Porosity generally embrittles ceramics. In contrast to such expectations, this report demonstrates that an effective fracture strain of nanoporous silica aerogels increases with increasing porosity. At ultralow relative densities of <0.5%, nanoporous monoliths start exhibiting super-compressible deformation with effective fracture strains of >50%. This is attributed to consequences of an ...
Wu Haibo - - 2012
Four chiral organosilanes based on O,O'-dibenzoyl tartardiamide, O,O'-bis-(3,5-dimethylbenzoyl) tartardiamide, O,O'-bis-(phenylcarbamoyl) tartardiamide and O,O'-bis-[(3,5-dimethylphenyl)carbamoyl] tartardiamide were synthesized and immobilized on silica to afford corresponding brush-type chiral stationary phases (CSPs) with well-defined structures. Using 54 compounds containing a wide variety of structures as analytes, the enantioselectivities of the four CSPs were evaluated ...
Kerr A - - 2012
BACKGROUND: Moving from sitting to walking (STW) is a functional movement that is sufficiently demanding to reveal early mobility problems that may be masked in other tests (Kerr et al., 2007). Research to date has confirmed the inherent difficulty of the STW movement (Magnan et al., 1996); however, the technology ...
Kenien Randall - - 2012
Radiolabeled cytochrome c (Cyt c), either as a free protein or as cell penetrating peptide (CPP)-conjugates, was tested for cellular uptake and nuclear transport in Human embryonic kidney293 (HEK293) cells and HeLa cells. Conjugation of Cyt c with either the amphipathic peptide model amphipathic peptide (MAP) or the cationic peptide ...
Zuaznabar-Gardona Julio C - - 2012
Multiwalled carbon nanotubes modified with 2-aminoethanethiol (MWNT-AET) were vertically self-assembled on gold electrodes with the assistance of chitosan and Tween. According to AFM and cyclic voltammetric determinations the best results were achieved using chitosan.
Li Chen - - 2012
Perylene imides have been an object of research for 100 years and their derivatives are key n-type semiconductors in the field of organic electronics. While perylene diimides have been applied in many electronic and photonic devices, their use can be traced back to the first efficient organic solar cell. By ...
Gilbert Shila - - 2012
Epithelial myosin light chain kinase (MLCK)-dependent barrier dysfunction contributes to the pathogenesis of inflammatory bowel diseases (IBD). We reported that epithelial GM-CSF-STAT5 signalling is essential for intestinal homeostatic response to gut injury. However, mechanism, redundancy by STAT5 or cell types involved remained foggy. We here generated intestinal epithelial cell (IEC)-specific ...
Metters Jonathan P - - 2012
We report the fabrication of gold screen printed macro electrodes which are electrochemically characterised and contrasted to polycrystalline gold macroelectrodes with their potential analytical application towards the sensing of chromium(iii) and (vi) critically explored. It is found that while these gold screen printed macro electrodes have electrode kinetics typically one ...
Kelleher I - - 2012
BACKGROUND: Psychotic symptoms occur more frequently in the general population than psychotic disorder and index risk for psychopathology. Multiple studies have reported on the prevalence of these symptoms using self-report questionnaires or clinical interviews but there is a lack of consensus about the prevalence of psychotic symptoms among children and ...
Cromwell Ian - - 2012
Erlotinib has been approved as a third-line treatment for advanced non-small-cell lung cancer (NSCLC) in British Columbia (BC). A cost-effectiveness analysis was conducted to compare costs and effectiveness in patients who received third-line erlotinib to those in a historical patient cohort that would have been eligible had erlotinib been available. ...
Wang Yu - - 2012
The electronic properties of graphene sheets decorated with nanodiamond (ND) particles have been investigated. The chemical fusion of ND to the graphene lattice creates pockets of local defects with robust interfacial bonding. At the ND-bonded regions, the atoms of graphene lattice follow sp3-like bonding and such regions play the role ...
Park Si Yun - - 2012
Transfer characteristics of ZnO thin-film transistors (TFTs) based on ZnO doped with various alkali metals. A new doping method is demonstrated by employing alkali metals to achieve high-performance and solution-processed ZnO TFTs with a low processing temperature (∼300 °C), which is applicable to flexible plastic substrates.
Rosa David - - 2012
A palladium-catalysed, tandem cyclopropanol rearrangement and direct arylation approach for the synthesis of 1-indanones is reported. The reaction is generally high yielding, uses oxygen as the terminal oxidant and tolerates a range of functional groups on the aryl ring.
Dag Omer - - 2012
A simple reaction between a mild reducing agent such as a trialkoxysilane and Ge(IV) species such as germanium tetraalkoxides in a room-temperature water/alcohol solution produces silica-coated ultrasmall (2-3 nm) amorphous germanium nanoparticles (na-Ge/SiO(2) ). The initial reaction involves the straightforward hydrolysis and condensation of the precursors, Ge(OCH(2) CH(3) )(4) and ...
Elavsky Steriani - - 2012
Physical activity (PA) may be a useful tool in the management of menopausal hot flashes (HFs) but findings are generally inconsistent. There are few well-designed and sufficiently powered RCTs. Applying a longitudinal within-person approach offers an alternative way to examine the PA-HFs relationship which enables complete accommodation of inter-individual differences. ...
Sharma Vivek - - 2012
Cobalamin deficiency commonly presents with a wide range of neuropsychiatric manifestations ranging from myelopathy, neuropathy, optic neuritis and dementia to mood disorders, chronic fatigue and psychosis even without classical hematological abnormalities like anemia and macrocytosis. However, obsessive compulsive disorder (OCD) in relation to vitamin B12 deficiency has not been described ...
Peng Chengxin - - 2012
In this paper, we report a facile ultrasonic method to synthesize well-dispersed CoO quantum dots (3~8 nm) on graphene nanosheets at room temperature by employing Co4(CO)12 as cobalt precursor. The prepared CoO/graphene composites displayed high performance as an anode material for lithium-ion battery, such as high reversible lithium storage capacity ...
Díaz Julián A - - 2012
Methods for combining multiple functions into well-defined nanomaterials are still lacking, despite their need in nanomedicine and within the broader field of nanotechnology. Here several strategies for controlling the amount and the ratio of combinations of labeled DNA on 13-nm gold nanoparticles using self-assembly of thiolated DNA and/or DNA-directed assembly ...
Nagaoka Yasutaka - - 2012
Binary assemblies of CdSe/CdS semiconductor nanorods are prepared with spherical metal nanoparticles intercalated into aligned, parallel nanorod arrays. Mechanistic studies suggest that the formation of these binary assemblies is a kinetically limited process. Organic additives with suitable polarity and strong affinity to spherical nanoparticles that have both a high dielectric ...
van Dieren S - - 2012
Aims: To determine the baseline characteristics and glucose lowering therapies associated with weight change among patients with type 2 diabetes. Materials and methods: 11,140 participants in the ADVANCE trial, were randomly assigned to an intensive (aiming for an HbA(1c) ≤ 6.5%) or a standard blood glucose control strategy. Weight was ...
León Emilio A - - 2012
Foot-and-mouth disease (FMD) is the paradigm of a transboundary animal disease. Beyond any doubt, it is the most serious challenge for livestock's health. Official Veterinary Services from free countries invest considerable amount of money to prevent its introduction, whereas those from endemic countries invest most of their resources in the ...
Sturlaugson Adam L - - 2012
Optical heterodyne-detected optical Kerr effect (OHD-OKE) measurements on a series of 1-alkyl-3-methylimidazolium tetrafluoroborate room-temperature ionic liquids (RTILs) as a function of chain length and water concentration are presented. The pure RTIL reorientational dynamics are identical in form to other molecular liquids studied previously by OHD-OKE (two power laws followed by ...
Waldron-Perrine Brigid - - 2012
OBJECTIVE/METHODS: The Montreal Cognitive Assessment (MoCA) is a brief yet comprehensive cognitive instrument used to assess level of impairment in neurological populations. The purpose of the present study was to assess the ability of the MoCA to detect cognitive impairment in a veteran patient population referred for neuropsychological testing and ...
Gibon Julien - - 2012
Hyperforin is one of the main bioactive compounds that underlie the antidepressant actions of the medicinal plant Hypericum perforatum (St. John's wort). However, the effects of a chronic hyperforin treatment on brain cells remains to be fully addressed. The following study was undertaken to further advance our understanding of the ...
Gika Helen - - 2012
The analysis of amino acids presents significant challenges to contemporary analytical separations. The present paper investigates the possibility of retention prediction in hydrophilic interaction chromatography (HILIC) gradient elution based on the analytical solution of the fundamental equation of the multilinear gradient elution derived for reversed-phase systems. A simple linear dependence ...
Dontigny Eve - - 2012
Although there is evidence that nicotinic acetylcholine (Ach) receptors are influenced by ceramides, we do not currently know whether or not these sphingolipids can also regulate the muscarinic subtypes of Ach receptors. Using the whole-cell patch technique, we demonstrated that the effectiveness of the muscarinic receptor agonist pilocarpine, in enhancing ...
Yan Qiang - - 2012
A class of dialkoxyanthracene-containing diblock copolymers is synthesized which possesses visible light-responsivity. These copolymers can self-assemble into a micellar structure in water. Green visible light (540 nm) is able to scissor these anthracene species and cleave the diblock copolymer into two fragments, inducing disassembly of the self-assembled micelles.
Meng X J - - 2012
In the past two decades or so, a number of viruses have emerged in the global swine population. Some, such as porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2), cause economically important diseases in pigs, whereas others such as porcine torque teno virus (TTV), now ...
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