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Kameyama Kyohko - - 2012
SUMMARYNeospora caninum is an intracellular parasite that poses a unique ability to infect a variety of cell types by causing host cell migration. Although previous studies demonstrated that parasite-derived proteins could trigger host cell migration, the related molecules have yet to be determined. Our study aimed to investigate the relationship ...
Carvalho Mesquita Cristina - - 2012
The aim of this study was to verify the influence of a specific exercise program on the strength and resistance levels of lumbar flexors and extensors in warehouse workers. The population used in this randomized controlled trial included 557 warehouse male workers from a food distribution company in Oporto/Portugal. Upon ...
Holling Markus - - 2012
BACKGROUND: The clinical impact of routine neuropathologic examination of samples from patients with intracerebral hemorrhage (ICH) is unclear. METHODS: Therefore, we evaluated a consecutive series of 378 surgical specimens from patients with ICH concerning demographic data, localization of hemorrhage, preoperative clinical diagnosis and neuropathological diagnosis. RESULTS: Histological examination revealed the ...
Sabotič Jerica - - 2012
Proteolytic enzymes play essential metabolic and regulatory functions in many biological processes and also offer a wide range of biotechnological applications. Because of their essential roles, their proteolytic activity needs to be tightly regulated. Therefore, small molecules and proteins that inhibit proteases can be versatile tools in the fields of ...
Lam Edmond - - 2012
A novel nanocomposite was prepared by deposition of carbonate-stabilized Au nanoparticles (AuNPs) onto the surface of poly(diallyldimethyl ammonium chloride) (PDDA)-coated carboxylated nanocrystalline cellulose (NCC). The hybrid material possessed AuNPs (1.45% by weight) with an average diameter of 2.95 ± 0.06 nm. The catalytic activity of AuNP/PDDA/NCC for reducing 4-nitrophenol to ...
P Forsythe Laura - - 2012
PURPOSE: Sleep-related complaints are common in cancer survivors. Although daytime sleepiness and sleep duration are associated with poor functional status, quality of life, and mortality in the general population, little is known about these issues in long-term cancer survivors. This study examined differences in daytime sleepiness and sleep duration between ...
Xu Xiaoliang - - 2012
Promoted by diethyl azodicarboxylate, a novel and highly stereoselective synthesis of cis-β-enaminones via oxidative dehydrogenation and hydration of the substituted propargylamines was realized. The possible mechanism was also proposed.
Ebert Matthias P A - - 2012
Chemotherapy for advanced colorectal cancer leads to improved survival; however, predictors of response to systemic treatment are not available. Genomic and epigenetic alterations of the gene encoding transcription factor AP-2 epsilon (TFAP2E) are common in human cancers. The gene encoding dickkopf homolog 4 protein (DKK4) is a potential downstream target ...
Elferink M A G - - 2012
BACKGROUND: There is increased interest in locoregional recurrences of rectal cancer. Despite comparable locoregional recurrence rates in colon cancer, only a few studies on locoregional recurrences among colon cancer patients have been published. This study was designed to identify prognostic factors for locoregional recurrences among patients with colon cancer in ...
Vidal Magalhães Wagner - - 2012
In recent years, several studies have demonstrated the protective effect of Heat Shock Proteins (HSP) on different organs and tissues under stressful conditions. However, most research explores the performance of those molecular chaperones during immune responses or pathological conditions like cancer, whereas the number of studies related to the performance ...
Sarmiento Olga L - - 2012
OBJECTIVE: The present study aimed to evaluate the nutritional status of pregnant women in Colombia and the associations between gestational BMI and sociodemographic and gestational characteristics. DESIGN: Cross-sectional study. A secondary analysis was made of data from the 2005 Demographic and Health Survey of Colombia. SETTING: Bogotá, Colombia. SUBJECTS: Pregnant ...
Szeszenia-Dąbrowska Neonila - - 2012
Environmental exposure of the general population to asbestos in Poland is mainly due to degradation of very popular asbestos-cement products and the resultant release of the elementary asbestos fibres into the ambient air. Assessments of environmental pollution by asbestos were based on the volume of the raw material used, amount ...
Oshima Hiroko - - 2012
Accumulating evidence has indicated that inflammatory responses are important for cancer development. Epidemiological studies have shown that regular use of non-steroidal anti-inflammatory drugs (NSAIDs) reduces the risk of colon cancer development. Subsequently, mouse genetic studies have shown that cyclooxygenase (COX)-2, one of the target molecules of NSAIDs, and its downstream ...
Spivak Hadar - - 2012
BACKGROUND: Although laparoscopic adjustable gastric banding (LAGB) and laparoscopic Roux-en-Y gastric bypass (LRYGB) are the most common bariatric procedures performed in the past decade, little is known about their long-term (>5 years) outcomes. METHODS: A retrospective outcome study investigated 148 consecutive patients from a single practice who underwent LAGB from November ...
Birnkammer Tobias - - 2012
Bivalent histamine H<sub>2</sub> receptor (H<sub>2</sub>R) agonists were synthesized by connecting pharmacophoric 3-(2-amino-4-methylthiazol-5-yl)-, 3-(2-aminothiazol-5-yl)-, 3-(imidazol-4-yl)- or 3-(1,2,4-triazol-5-yl)-propylguanidine moieties by N<sup>G</sup>-acylation with alkanedioic acids of various chain lengths. The compounds were investigated for H<sub>2</sub>R agonism in GTPase and [<sup>35</sup>S]GTPγS binding assays at guinea-pig (gp) and human (h) H<sub>2</sub>R-GsαS fusion proteins including various ...
Sakowski Piotr - - 2012
The study aimed at assessment of the Polish occupational medicine service system after over ten years of functioning in the current shape, made by occupational nurses. The article focuses on the job satisfaction level among Polish occupational medicine nurses. The survey was performed among 600 randomly selected occupational medicine nurses, ...
Morales Cesar A - - 2012
Bacteriophage ΦCP24R was isolated from raw sewage from a waste treatment plant, and lytic activity was observed against a type A Clostridium perfringens isolate. Electron microscopy revealed a small virion (44-nm-diameter icosahedral capsid) with a short, non-contractile tail, indicative of a member of the family Podoviridae. The phage had a ...
Hong Chien-Chong - - 2012
This paper presents enhanced performance of anesthetic propofol biosensors by modifying molecularly imprinted nanocavities of biosensors. In this work, the relationship between molecularly imprinted nanocavities and performance of molecularly imprinted polymer (MIP) films is investigated. The morphological control of imprinted nanocavities on molecularly imprinted biosensors is done by adjusting polymer ...
Lokwani Deepak - - 2012
We present here the Energetic pharmacophore model representing complementary features of the 1,2,3,4-tetrahydropyrimidine for selective cyclooxygenase-2 (COX-2) inhibition. For the development of pharmacophore hypothesis, a total of 43 previously reported compounds were docked on active site of COX-2 enzyme. The generated pharmacophore features were ranked using energetic terms of Glide ...
Tirado Marcus - - 2012
While recent studies have shown that for some peptides, such as oligoglycines and Leu-enkephalin, mid-sized b fragment ions exist as a mixture of oxazolone and macrocycle structures, other primary structure motifs, such as QWFGLM, are shown to exclusively give rise to macrocycle structures. The aim of this study was to ...
Yamada Shinji - - 2012
Exposure of 4-azachalcones to HCl gas produced the corresponding HCl salts with a head-to-tail stacked alignment, irradiation of which produced the corresponding syn-HT dimers with high regio- and stereoselectivities, thus showing the effectiveness of the cascade process in crystals.
Gavin Michael C - - 2012
A 50-year-old woman presented with fatigue and shortness of breath. Dyspnea after moderate exertion had developed gradually, along with profound malaise and a nonproductive cough. In the 48 hours before admission, her shortness of breath had worsened.
Kondo Shunsuke - - 2012
BACKGROUND: c-Met is an oncogene encoding a receptor for hepatocyte growth factor and, as such, plays a key role in hepatocellular carcinomas (HCC). We evaluated c-Met protein expression and its gene amplification in order to assess whether they were related to tumor recurrence and survival rates among patients who had ...
Cha Jihoon - - 2012
OBJECTIVE: The aim of this work was to compare the prevalence of cyclops lesions after anterior cruciate ligament reconstruction (ACLR) using the single-bundle and remnant bundle preservation techniques. MATERIALS AND METHODS: One hundred consecutive patients, who had undergone postoperative MRI of the knee followed by arthroscopic ACLR with the remnant ...
Sišović Anica - - 2012
Polycyclic aromatic hydrocarbons (PAHs) were measured in the PM(10) particle fraction collected at two different measuring sites in Zagreb, Croatia. In summer, concentrations of all PAHs at both sites were low. In winter, mass concentrations of all PAHs measured at southern site were much higher than those at north. Contents ...
Viganò Luca - - 2012
BACKGROUND: Liver resection (LR) is the only potentially curative treatment of colorectal liver metastases (CRLM). Its outcome over the past 2 decades was studied using actual 5-year survival rates. METHODS: Data of 393 consecutive patients who underwent LR for CRLM at Mauriziano Umberto I (Turin) until June 2005 were analyzed. ...
Couronné Lucile - - 2012
A substantial fraction of T-cell lymphomas carry mutations in two genes - TET2 and DNMT3A - that are involved in DNA methylation. The co-occurrence of these mutations suggests that inhibitors of DNA methylation could possibly have antitumor effects in such patients.
Khan Abid Ali - - 2012
A simple, efficient and cost-effective method for municipal wastewater treatment is examined in this paper. The municipal wastewater is treated using an upflow anaerobic sludge bed (UASB) reactor followed by flash aeration (FA) as the post-treatment, without implementing aerobic biological processes. The UASB reactor was operated without recycle, at hydraulic ...
Capaccio Pasquale - - 2012
Aplasia of the major salivary glands is a rare condition due to an alteration in the development of the ectodermal tissue of the oral cavity often related to other craniofacial abnormalities or alteration of structures deriving from the first or second archial branch, in particular the lacrimal glands; it can ...
Chen Xueping - - 2012
Converging evidence indicates that SOD1 aggregation is a common feature of mutant SOD1-linked fALS, and seems to be directly related to the gain-of-function toxic property. However, the mechanism inducing the aggregation is not understood. To study the contribution of oxidative modification of cysteine residues in SOD1 aggregation, we systematically examined ...
Imhoff Roland - - 2012
The amount of time an individual spends gazing at images is longer if the depicted person is sexually appealing. Despite an increasing use of such response latencies as a diagnostic tool in applied forensic settings, the underlying processes that drive the seemingly robust effect of longer response latencies for sexually ...
Yang Dongming - - 2012
A series of germylene, stannylene and plumbylene complexes [η(2)(N,N)-Me(2)Si(DippN)(2)Ge:] (3a), [η(2)(N,N)-Ph(2)Si(DippN)(2)Ge:] (3b), [η(2)(N,N)-Me(2)Si(DippN)(2)Sn:] (4), [η(2)(N,N)-Me(2)Si(DippN)(2)Pb:](2) (5a), and [η(2)(N,N)-Ph(2)Si(DippN)(2)Pb:] (5b) (Dipp = 2,6-iPr(2)C(6)H(3)) bearing bulky bis(amido)silane ligands were readily prepared either by the transamination of M[N(SiMe(3))(2)](2) (M = Sn, Pb) and [Me(2)Si(DippNH)(2)] or by the metathesis reaction of bislithium bis(amido)silane [η(1)(N),η(1)(N)-R(2)Si(DippNLi)(2)] ...
Wu Yi-Hua - - 2012
We conducted a study to investigate the characteristics and determinants of ambient bacteria in Taipei, Taiwan from August 2004 to March 2005. We monitored ambient culturable bacteria in Shin-Jhuang City, an urban area in the Taipei metropolitan areas, using duplicate Burkard Portable Air Samplers with R2A agar. The average concentration ...
Oliveira Camila B - - 2012
SUMMARYTrypanosoma evansi is the aetiological agent of trypanosomosis in domestic animals. In this pathology, an inflammatory response can be observed and, as a consequence, the increase of extracellular adenine nucleotides such as ATP. These nucleotide concentrations are regulated by ectoenzymes such as NTPDase (EC 3.6.1.5, CD39), which catalyses the hydrolysis ...
- - 2012
To the Editor: El-Serag (Sept. 22 issue)(1) recommends that for diagnosis of hepatocellular carcinoma in patients with cirrhosis, lesions greater than 2 cm in diameter require one study with typical imaging features, whereas lesions 1 to 2 cm in diameter require concordant findings from computed tomography (CT) and magnetic resonance ...
Ji Bingbing - - 2012
After an initial phase of growth and development, bone undergoes a continuous cycle of repair, renewal and optimisation by a process called remodelling. This paper describes a novel mathematical model of the trabecular bone remodelling cycle. It is essentially formulated to simulate a remodelling event at a fixed position in ...
Le Guigo Pauline - - 2012
A plant's own characteristics, but also those of its neighbors, might have an impact on its probability of being colonized by herbivorous insects. A plant might be less colonized and experience associational resistance when it grows near repellent neighbors. In contrast, it might be more colonized and experience associational susceptibility ...
Li Changyan - - 2012
Resistant germplasm resources are valuable for developing resistant varieties in agricultural production. However, recessive resistance genes are usually overlooked in hybrid breeding. Compared with dominant traits, however, they may confer resistance to different pathogenic races or pest biotypes with different mechanisms of action. The recessive rice bacterial blight resistance gene ...
Brose Rebecca Deering - - 2012
X-linked adrenoleukodystrophy (XALD), a neurological disorder caused by mutations in the peroxisomal membrane protein gene ABCD1, presents as a rapidly progressing, inflammatory cerebral demyelination (cerebral cases) or a slowly progressing, distal axonopathy (non-cerebral cases). Specific ABCD1 defects do not explain this significant phenotypic variation. Patients have increased plasma and tissue ...
Ellegaard Karen - - 2012
In 90% of patients with rheumatoid arthritis (RA), the joints of the hand are affected. Studies of grip strength training have not indicated a negative effect on disease activity after training. Introduction of ultrasound Doppler (USD) to measure increased blood flow induced by inflammation has made it possible to investigate ...
Miernik Arkadiusz - - 2012
BACKGROUND: Different types of single-incision laparoscopic surgery (SILS) have become increasingly popular. Although SILS is technically even more challenging than conventional laparoscopy, published data of first clinical series seem to demonstrate the feasibility of these approaches. Various attempts have been made to overcome restrictions due to loss of triangulation in ...
Rezende Marcelo - - 2012
BACKGROUND: In prolonged laparoscopic procedures, hypothermia is frequently observed. The possible influence of the vasodilating action of CO(2), due to its increased levels in the blood during the laparoscopic procedures, has yet to be studied. The objective of this study was, therefore, to evaluate body temperature patterns in pigs subjected ...
Torres Roger - - 2012
Two virus isolates, T1 and T2, causing necrotic spots on leaves and stems of pepper and tomato, respectively, were isolated in the La Joya valley, Arequipa, Peru, in 2010. These two isolates were inoculated to differential hosts for tospoviruses and showed differential fitness: T1 induced necrotic local lesions in Vigna ...
Olofsson R - - 2012
BACKGROUND: Isolated limb perfusion with tumor necrosis factor alpha and melphalan (TM-ILP) has proven to be a successful option in treating advanced soft tissue sarcomas (STS), where amputation otherwise is needed to achieve safe surgical margins. METHODS: From 2000 to 2009, 54 patients with locally advanced STS, who all were ...
Pramanik Suman - - 2012
Three-component synthesis of protected secondary and "for the first time" tertiary homoallylic amines is achieved from carbonyl, carbamate, and allyltrimethylsilanes using a Re(2)O(7)-catalyst under mild and open flask conditions. Excellent chemoselectivities and diastereoselectivities were observed.
Vassiliou Vassilios S - - 2012
To the Editor: In the article by Granger et al. describing the results of the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) study (Sept. 15 issue),(1) it was disappointing that patients with atrial fibrillation who were treated with warfarin had an international normalized ratio ...
Youk Ji Hyun - - 2012
To determine the time when follow-up ultrasound (US) should begin for concordant benign lesions after US-guided 14-gauge core needle breast biopsy (CNB). This was an IRB-approved retrospective study, with a waiver of informed consent. Among 3,888 consecutive US-guided CNBs performed between August 2005 and March 2008, 1,492 breast masses in ...
Araujo Paulo H - - 2012
PURPOSE: The purpose of this study was to evaluate three different non-invasive measuring devices for the pivot shift phenomenon with reference to direct bony movement measured by an electromagnetic device rigidly attached to the tibia and femur. METHODS: A lower body cadaveric specimen was prepared to create a positive pivot ...
Nabavi Seyed Fazel - - 2012
Toxic and essential elements levels (chromium, copper, iron, manganese, nickel, lead, cadmium, and zinc) have been determined in the brain, heart, liver, gill, gonads, spleen, bile and muscle of S. lucioperca, collected from the Caspian Sea by employing Flame- Atomic absorption spectrometry. Results indicated that nearly all of the toxic ...
Mesías Marta - - 2012
OBJECTIVE: To evaluate Zn utilization and status among a sample of Spanish boys consuming a diet based on Mediterranean patterns. DESIGN: Dietary Zn balance was assessed by means of Zn intake in food and Zn output in faeces and urine as measured by flame atomic absorption spectrophotometry. In addition, biomarkers ...
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