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Results 401 - 450 of 3980
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Mauch J - - 2011
BACKGROUND: Several reports have confirmed the efficacy of Intralipid® (containing soya bean oil, egg phospholipids, glycerin and water) in the therapy of systemic local anesthetic intoxication. Pretreatment with Intralipid® shifted the dose-response to bupivacaine-induced asystole in rats. Whether intravenous anesthesia with propofol in the widely used medium chain triglyceride lipid ...
Heyries Kevin A - - 2011
We present a microfluidic 'megapixel' digital PCR device that uses surface tension-based sample partitioning and dehydration control to enable high-fidelity single DNA molecule amplification in 1,000,000 reactors of picoliter volume with densities up to 440,000 reactors cm(-2). This device achieves a dynamic range of 10(7), single-nucleotide-variant detection below one copy ...
Ogawa Yoshikazu - - 2011
BACKGROUND: Rathke's cleft cyst is known as an indolent disease, but has become intractable in a few cases. In this clinical investigation, the initial operative outcomes of Rathke's cleft cyst and the mechanism of re-accumulation were investigated to identify the optimum surgical strategy for the second operation. METHODS: We conducted ...
Bettini Vera V Department of Medical and Surgical Sciences, School of Medicine, University of Padua, Padua, - - 2012
Alström syndrome (ALMS) is a rare autosomal recessive monogenic disease associated with obesity, hyperinsulinemia, and alterations of glucose metabolism that often lead to the development of type 2 diabetes at a young age. To study the relationship between weight and metabolism in a group of ALMS patients and matched controls. ...
Pillukat T - - 2011
OBJECTIVE: Treatment of pyogenic flexor tenosynovitis within the osteofibrous channel of the thumb and finger by insertion of a closed irrigation system. INDICATIONS: Pyogenic tenosynovitis of the flexor tendons of the hand. CONTRAINDICATIONS: Necrosis of the flexor tendons or flexor tendon sheath, gangrene of the finger, extensive loss of soft ...
Navaneethan Udayakumar - - 2011
BACKGROUND AND AIM: We recently reported mucosal infiltration of IgG4-expressing plasma cells in a patient with chronic antibiotic-refractory pouchitis (CARP). The role of serum IgG4 in the pathogenesis and clinical course of ileal pouch disorders has not been investigated. We hypothesized that IgG4-mediated autoimmunity may be a contributing factor in ...
Hodgson Brian D - - 2011
PURPOSE: This study seeks to investigate the use of extra-orally applied near-infrared phototherapy for the reduction of oral pain secondary to chemotherapy- and radiation therapy-induced mucositis in adult and pediatric hematopoietic stem cell transplant (HSCT) patients. METHODS: Eighty HSCT patients were divided into regular (R) and low (L) risk groups, ...
Puram Sidharth V SV Department of Pathology, Harvard Medical School, Boston, Massachusetts, - - 2011
The protein kinase calcium/calmodulin-dependent kinase II (CaMKII) predominantly consists of the α and β isoforms in the brain. Although CaMKIIα functions have been elucidated, the isoform-specific catalytic functions of CaMKIIβ have remained unknown. Using knockdown analyses in primary rat neurons and in the rat cerebellar cortex in vivo, we report ...
Wang Jing-Jy - - 2011
wang j.-j. (2011) A structural model of the bio-psycho-socio-spiritual factors influencing the development towards gerotranscendence in a sample of institutionalized elders. Journal of Advanced Nursing. ABSTRACT: Aims.  This paper is a report of a study to determine the bio-psycho-socio-spiritual factors influencing the development towards gerotranscendence in institutionalized older people. Physical ability, ...
Argiriou Anagnostis - - 2011
The actin-binding protein profilin (PRF) plays an important role in cell growth and expansion by regulating the organization of the actin filaments. Recent studies have reported association between fiber elongation in cultivated cotton (Gossypium hirsutum) and PRF expression. In the present study, we cloned four genomic clones from allotetraploid cotton ...
Szczerbowska-Boruchowska Magdalena - - 2011
Synchrotron-radiation-based X-ray fluorescence was applied to the elemental microimaging of neoplastic tissues in cases of various types of brain tumors. The following cases were studied: glioblastoma multiforme, gemistocytic astrocytoma, oligodendroglioma, anaplastic oligodendroglioma, ganglioglioma, fibrillary astrocytoma, and atypical transitional meningioma. Apart from neoplastic tissue, the analysis included areas of tissue apparently ...
Chu M X - - 2011
Single nucleotide polymorphisms of 5' regulatory region of follicle-stimulating hormone receptor (FSHR) gene were detected in two high prolificacy sheep breeds (Small Tail Han and Hu sheep) and two low prolificacy sheep breeds (Corriedale and Chinese Merino sheep) by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP). The results indicated that ...
Hanna Richard N RN Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, California, - - 2011
The transcription factors that regulate differentiation into the monocyte subset in bone marrow have not yet been identified. Here we found that the orphan nuclear receptor NR4A1 controlled the differentiation of Ly6C- monocytes. Ly6C- monocytes, which function in a surveillance role in circulation, were absent from Nr4a1-/- mice. Normal numbers ...
Schmidt Anne Mette - - 2011
It was hypothesised that increased exercise capacity is related to improved quality of life (QoL) in patients with cystic fibrosis (CF). A 12-week individually tailored unsupervised aerobic exercise programme was offered to 42 patients with CF. At the start and at the end of the exercise programme, data on QoL, ...
Paul Asosii - - 2011
The present manuscript describes cloning and expression characterization of alpha-tubulin (CsTUA) gene in an evergreen tree tea [Camellia sinensis (L.) O. Kuntze] in response to winter dormancy (WD), abiotic stresses (sodium chloride, polyethylene glycol, and hydrogen peroxide) and plant growth regulators [abscisic acid (ABA), gibberellic acid (GA(3)), indole-3-butyric acid (IBA), ...
Kurebayashi Hidekazu - - 2011
Spin currents-the flow of angular momentum without the simultaneous transfer of electrical charge-play an enabling role in the field of spintronics. Unlike the charge current, the spin current is not a conservative quantity within the conduction carrier system. This is due to the presence of the spin-orbit interaction that couples ...
Garcia-Gonzalo Francesc R FR Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, - - 2011
Mutations affecting ciliary components cause ciliopathies. As described here, we investigated Tectonic1 (Tctn1), a regulator of mouse Hedgehog signaling, and found that it is essential for ciliogenesis in some, but not all, tissues. Cell types that do not require Tctn1 for ciliogenesis require it to localize select membrane-associated proteins to ...
Potaczek Daniel P - - 2011
The high affinity immunoglobulin E (IgE) receptor (FcεRI) plays a key role in the pathogenesis of atopy and allergic disorders. Several polymorphisms located in 5'-flanking region and 5'-untranslated region (5'-UTR) of human FCER1A, the gene encoding FcεRI α-subunit, have been shown to functionally affect its transcriptional activity. All those genetic ...
Yuk Jae-Min - - 2011
The orphan nuclear receptor SHP (small heterodimer partner) is a transcriptional corepressor that regulates hepatic metabolic pathways. Here we identified a role for SHP as an intrinsic negative regulator of Toll-like receptor (TLR)-triggered inflammatory responses. SHP-deficient mice were more susceptible to endotoxin-induced sepsis. SHP had dual regulatory functions in a ...
Harrington Sophie A - - 2011
Ferroelectric materials are used in applications ranging from energy harvesting to high-power electronic transducers. However, industry-standard ferroelectric materials contain lead, which is toxic and environmentally unfriendly. The preferred alternative, BaTiO(3), is non-toxic and has excellent ferroelectric properties, but its Curie temperature of ∼130 °C is too low to be practical. Strain ...
Van De Mortel Thea F - - 2011
van de mortel t.f., kermode s., progano t. & sansoni j. (2011) A comparison of the hand hygiene knowledge, beliefs and practices of Italian nursing and medical students. Journal of Advanced Nursing. ABSTRACT: Aim.  This paper reports a study examining the hand hygiene knowledge, beliefs and practices of Italian nursing ...
Pommer Bernhard - - 2011
Pommer B, Frantal S, Willer J, Posch M, Watzek G, Tepper G. Impact of dental implant length on early failure rates: a meta-analysis of observational studies. J Clin Periodontol 2011; doi: 10.1111/j.1600-051X.2011.01750.x. ABSTRACT: Aim: To test the null hypothesis of no difference in failure rates of short (minimum length: 7 mm) ...
Simpson R E - - 2011
Phase-change memory technology relies on the electrical and optical properties of certain materials changing substantially when the atomic structure of the material is altered by heating or some other excitation process. For example, switching the composite Ge(2)Sb(2)Te(5) (GST) alloy from its covalently bonded amorphous phase to its resonantly bonded metastable ...
Meretoja Riitta - - 2011
meretoja r. & koponen l. (2011) A systematic model to compare nurses' optimal and actual competencies in the clinical setting. Journal of Advanced Nursing. ABSTRACT: Aim.  This paper is a report of a study to develop a model to compare nurses' optimal and actual competencies in the clinical setting. Background.  Although ...
Juuti Anna-Kaisa - - 2011
PURPOSE: We investigated the prevalence, natural course, and associated risk factors of habitual snoring (HS) and restless legs syndrome (RLS) over a period of 10 years among an aging population from their early sixties to their seventies. METHODS: A population-based follow-up study among all persons born in 1935 and living in ...
Kampf Christopher J - - 2011
This study concerns the development and validation of a complete method for the analysis of two highly reactive α-dicarbonyl compounds, glyoxal (Gly) and methylglyoxal (Mgly), in atmospheric fine particulate matter (PM(2.5)). Method development included optimization of sample preparation procedures, e.g., filter extraction, concentration of extracts, derivatization and solid-phase extraction (SPE) ...
Tanboga Ibrahim H - - 2011
Syntax score is a significant tool in the management of complex coronary artery disease (CAD). This score is based on visual assessment of coronary lesions via coronary angiograms. It has some limitations due to its visual assessment. Therefore, interobserver and intraobserver agreement should be tested. One hundred twenty-two coronary angiograms ...
Tokunaga K - - 2011
Tokunaga K, Seto H, Ohba H, Mihara C, Hama H, Horibe M, Yoneda S, Nagata T. Topical and intermittent application of parathyroid hormone recovers alveolar bone loss in rat experimental periodontitis. J Periodont Res 2011; doi: 10.1111/j.1600-0765.2011.01386.x. © 2011 John Wiley & Sons A/S Background and Objective:  Periodontitis is characterized ...
Hodt-Billington Caroline - - 2011
Gait symmetry is often a goal for physiotherapy in patients with hip osteoarthritis and after total hip replacement. However, there is no agreement on criteria for pathological gait asymmetry. In this study we investigated discriminative abilities of trunk and footfall gait symmetry measures, and thereafter assessed whether a 10% cutoff ...
Barofsky Ivan - - 2011
The aim of this paper is to examine the oft-heard concern that quality or quality-of-life cannot be defined. This concern persists today, even in the presence of countless studies that claim to be assessing quality or quality-of-life. There is obviously a disconnect here that warrants some attention, if not explanation. ...
Neklesa Taavi K TK Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, - - 2011
The ability to regulate any protein of interest in living systems with small molecules remains a challenge. We hypothesized that appending a hydrophobic moiety to the surface of a protein would mimic the partially denatured state of the protein, thus engaging the cellular quality control machinery to induce its proteasomal ...
Guillet Valérie - - 2011
Microtubule nucleation in all eukaryotes involves γ-tubulin small complexes (γTuSCs) that comprise two molecules of γ-tubulin bound to γ-tubulin complex proteins (GCPs) GCP2 and GCP3. In many eukaryotes, multiple γTuSCs associate with GCP4, GCP5 and GCP6 into large γ-tubulin ring complexes (γTuRCs). Recent cryo-EM studies indicate that a scaffold similar ...
Arnts Inge J J - - 2011
The aim of this study was to evaluate the effect of heparin versus saline as flush solution for maintaining patency in peripheral intravenous locks in neonates and to investigate whether other variables influence the longevity of intravenous locks. Heparin is usually used as a regular flush solution to prevent occlusion ...
Balasubramanium Radish Kumar - - 2012
In spite of voice being an important parameter of mate choice, none of the studies have described the acoustic characteristics of the sexually appealing voice. Two hundred adults (100 men and 100 women) in the age range of 18-24 years were asked to narrate a topic, which was recorded directly ...
Malkoun Nadia - - 2011
We report retrospective data on the feasibility and efficacy of prolonging adjuvant temozolomide (TMZ) more than 6 months after chemoradiotherapy completion in patients with glioblastoma (GBM). Molecular prognostic factors were assessed. Data from 46 patients were reviewed. Patients received postoperative irradiation, 60 Gy in 30 fractions, combined with concurrent TMZ, 75 mg/m(2). Four ...
Brunsing Ryan L RL Department of Cell Biology and Physiology, University of New Mexico Health Science Center, Albuquerque, NM, - - 2011
Interleukin-10 (IL-10) is a potent suppressor of the immune system, commonly produced by CD4(+) T cells to limit ongoing inflammatory responses minimizing host damage. Many autoimmune diseases are marked by large populations of activated CD4(+) T cells within the setting of chronic inflammation; therefore, drugs capable of inducing IL-10 production ...
Knaapila Antti - - 2011
Androstenone (5α-androst-16-en-3-one) and other androstenes, body odor components occurring in apocrine secretions, may play a role in human chemosignaling. We hypothesized that the odor of androstenone may gain hedonic value from sexual intercourse experiences via associative learning. Young adults (N = 397, 61.5% women, age 21-24 years, randomly sampled regarding sexual experience) rated ...
Fortea-Ormaechea José Ignacio - - 2011
To evaluate effectiveness and safety of adalimumab in CD patients of the Madrid area and identify predictors of response. Multicenter retrospective survey of all CD patients treated with adalimumab in 9 hospitals of the Madrid area (Spain). Univariate and multivariate analysis of predictors of response was performed. 174 patients included ...
Hiranuma Yojiro - - 2011
We investigated solvation structures of I- on and below a surface of an aqueous solution by photodetachment spectroscopy. An aqueous solution of an alkali halide was introduced into the vacuum as a continuous liquid flow (liquid beam), and the liquid beam was irradiated with a UV laser pulse. The intensity ...
Aslan M - - 2011
Association of some neurotropic viruses like Borna Disease virus and Herpes virus with schizophrenia is better explained. However, the role of West Nile virus (WNV) infection in schizophrenia is not well documented. Therefore, this study was performed to investigate possible association between schizophrenia and presence of antibodies and WNV RNA ...
Cocco Emiliano - - 2011
We evaluated the expression of tissue factor (TF) in ovarian cancer (EOC) and the potential of hI-con1, an antibody-like molecule targeting TF, as a novel form of therapy against chemotherapy-resistant ovarian disease. We studied the expression of TF in 88 EOC by immunohistochemistry (IHC) and real-time-PCR (qRT-PCR) and the levels ...
Keusgen Michael - - 2011
Marasmin, which is especially known from the two South African species Tulbaghia alliacea and Tulbaghia violacea, but was also described for the garlic mushroom Marasmius alliaceus, is the precursor of the thiosulfinate marasmicin. Marasmicin has attracted considerable attention because of its antifungal and tuberculostatic activity. However, many Allium species of ...
Mattsson Sören - - 2011
New imaging technologies utilising X rays and radiopharmaceuticals are continuously under development. The benefit of computed tomography (CT) has been so dramatic that there is a tendency to overuse it and not to place enough efforts into optimisation of the technique. It is also now more and more common to ...
Kanno Hiromi - - 2011
Lymphoplasmacyte-rich meningioma (LPRM), the most rare variant of meningiomas, features extensive lymphoplasmacytic infiltrates. Although the jugular foramen (JF) is occasionally involved by several types of tumor, such as paragangliomas and schwannomas, meningioma in the JF is an infrequent disease. Here we present an extremely rare case of LPRM found in ...
Huvaere Kevin - - 2011
The effect of two different antioxidants, EDTA and green tea extract (GTE), used individually or in combination, on the light-induced oxidation of reduced fat soft cheeses (0.2 and 6% fat) was investigated. In samples with 0.2% fat, lipid hydroperoxides as primary lipid oxidation products were not detected but their interference ...
Day Judd S JS Implant Research Center, School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, PA, USA. - - 2012
Reverse total shoulder arthroplasty has been used to treat rotator cuff tear arthropathy and proximal humerus fractures, as well as for failed conventional total shoulder prostheses. It has been suggested that polyethylene wear is potentially higher in reverse shoulder replacements than in conventional shoulder replacements. The modes and degree of ...
Macri Elisa V - - 2011
BACKGROUND: High-fat diets are usually associated with greater weight (W) gain and body fat (BF). However, it is still unclear whether the type and amount of fat consumed influence BF. Additionally, dietary fat intake may also have consequences on skeletal health. OBJECTIVE: To evaluate in healthy growing rats the effects ...
Ben-Hadj-Khalifa Sonia - - 2011
In addition to its established immuno-regulating capacity, the anti-inflammatory cytokine interleukin (IL)-10 exerts direct effects on coagulation. IL-10 down regulates the expression of tissue factor (TF) and thrombin generation (TG). Thus, we hypothesised that IL-10 could enhance the effect of anticoagulants. To evaluate in vitro the potential additive effect of ...
Geisler Tobias - - 2011
PURPOSE: Platelet-derived stromal-cell-derived factor-1 (SDF-1) plays an important role in trafficking hematopoetic progenitor cells for tissue regeneration and neovascularisation. The aim was to evaluate platelet-SDF-1 and CD34(+) progenitor cells in patients with acute myocardial infarction (AMI) compared with hemodynamic function and infarct size using late gadolinium enhancement (LGE) cardiac magnetic ...
Zhong Fangfang - - 2011
Human soluble guanylate cyclase (sGC), a critical heme-containing enzyme in the NO-signaling pathway of eukaryotes, is an αβ heterodimeric hemoprotein. Upon the binding of NO to the heme, sGC catalyzes the conversion of GTP to cyclic GMP, playing a crucial role in many physiological processes. However, the specific contribution of ...
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