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Bender A - - 2011
Forces measured in human joints vary considerably when an activity such as walking is carried out by different subjects or when it is repeated. 'Typical' standardised force-time patterns are needed to test and improve joint implants. Mechanically most important for their endurance are the magnitudes and times of force maxima ...
Lin Pao-Chen - - 2011
Objectives: The aim of this study was to explore the prevalence of depressive symptoms and the risk factors that correlated with depressive symptoms among elders living alone. Methods: A cross-sectional design was implemented. The sample consisted of 117 women and 75 men aged 65 and older who living alone in ...
Chandrasekhar Vadapalli - - 2011
The reaction of the phosphorus trihydrazide, (S)P[N(Me)-NH(2)](3) (1) with quinoline-2-carboxaldehyde (C(9)H(6)N-2-CHO) in a 1 : 3 ratio afforded a trishydrazone, (S)P[N(Me)-N[double bond, length as m-dash]CH-2-C(9)H(6)N](3) (2). Crystals of 2 were grown in three different solvent media affording an unsolvated (2, monoclinic, P2(1)/n) and two solvated (2·3H(2)O, trigonal, R3 and 2·2CH(3)OH, triclinic, P1[combining ...
Kais Z Z Department of Biomedical Informatics and the Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, - - 2012
We analyzed the effects of 14 different missense mutations in the RING domain of BRCA1 on the function of the protein in the control of centrosome number in tissue culture cells. Whereas 2 of the 14 BRCA1 variant proteins were neutral in the centrosome duplication assay, missense mutations of zinc-coordinating ...
Steffen H - - 2011
In children with congenital glaucoma the functional long-term result is often disappointing even if the intraocular pressure is well controlled. The reason for this discrepancy is attributed to amblyogenic factors responsible for interfering with normal visual development. These amblyogenic factors are corneal edema, irregular astigmatism and non-corrected ametropia as monocular ...
Borisch N - - 2011
OBJECTIVE: Correction of swan neck deformity at the PIP and DIP joint by reconstruction of the oblique retinacular ligament through palmar transposition of one distally pedicled lateral band (oblique retinacular ligament reconstruction (ORL) = Littler II). INDICATIONS: Rheumatoid swan neck deformity Nalebuff stages I-III (dynamic, partially contracted, contracted). The swan neck deformity should be ...
Sugano Yuya - - 2011
Klotho is an aging suppressor gene. In mice, loss of Klotho function causes accelerated aging while increased Klotho expression increases longevity. This study aimed to identify and characterize the orthologue of Klotho in zebrafish, a powerful model organism for the investigation of development and human disease. Zebrafish klotho was identified ...
Gamberini M Cristina - - 2011
A study of the composition of the remains of ancient ointments from museums was undertaken to enable understanding of the preparation techniques. Comparison of ancient recipes from different historical periods and spectroscopic characteristics of inorganic and/or organic remains recovered in museum vessels enabled preparation of ancient pharmaceutical-cosmetic formulations. Farmacopea Augustana ...
Slover Robert H - - 2011
Slover RH, Welsh JB, Criego A, Weinzimer SA, Willi SM, Wood MA, Tamborlane WV. Effectiveness of sensor-augmented pump therapy in children and adolescents with type 1 diabetes in the STAR 3 study. Objective: Maintenance of appropriate A1C values and minimization of hyperglycemic excursions are difficult for many pediatric patients with ...
Meng Xian-zhong - - 2011
Patients with os odontoideum always present instability in atlantoaxial joint and need atlantoaxial fixation. C2 pedicle or laminar screws fixation has proven to be efficient and reliable for atlantoaxial instability. However, os odontoideum is a congenital or developmental disease, featured with anomalous bony anatomies. The anatomic measurements and guidelines for ...
Wang Xiao-Bing - - 2011
Macrophage migration inhibitory factor (MIF) plays a critical role in tumorigenesis. We aim to examine the association of MIF with tumor recurrence and survival of gliomas, and to determine whether MIF is a valuable prognostic predictor for glioma patients. The expression of MIF and interleukin 8 (IL-8) was evaluated in ...
Li Fei F Department of Biology, New York University, New York, New York 10003, USA. - - 2011
Histone modification marks have an important role in many chromatin processes. During DNA replication, both heterochromatin and euchromatin are disrupted ahead of the replication fork and are then reassembled into their original epigenetic states behind the fork. How histone marks are accurately inherited from generation to generation is still poorly ...
Lazar Josef - - 2011
Membrane proteins are a large, diverse group of proteins, serving a multitude of cellular functions. They are difficult to study because of their requirement of a lipid membrane for function. Here we show that two-photon polarization microscopy can take advantage of the cell membrane requirement to yield insights into membrane ...
Francis Richard P - - 2011
TENS can be administered in conventional (high frequency, low intensity) or acupuncture-like (AL-TENS: low frequency, high intensity) formats. It is claimed that AL-TENS produces stronger and longer-lasting hypoalgesia than conventional TENS, although evidence is lacking. This randomised controlled parallel group study compared the effects of 30 minutes of AL-TENS, conventional ...
Macphee Maura - - 2011
macphee m., skelton-green j., bouthillette f. & suryaprakash n. (2011) An empowerment framework for nursing leadership development: supporting evidence. Journal of Advanced Nursing. ABSTRACT: Aim.  This article is a report on a descriptive study of nurse leaders' perspectives of the outcomes of a formal leadership programme. Background.  Effective nurse leaders are ...
van Nie-Visser Noémi C - - 2011
Aims and objectives.  This study investigates possible differences in malnutrition prevalence rates in Dutch and German nursing homes. It seeks to provide insight into the screening, prevention and treatment of malnutrition and the indicators for nutritional care policy. Background.  For decades, malnutrition has been an important problem in health care ...
Kolber Morey J - - 2011
This study investigated the reliability and concurrent validity of active shoulder elevation in the scapular plane (scaption) using a digital inclinometer and goniometer. Two investigators used a goniometer and digital inclinometer to measure scaption on 30 asymptomatic participants in a blinded repeated measures design. Good reliability was present with intraclass ...
Kasap Murat - - 2011
Stem cell markers are utilized to isolate or identify stem cells. So far, many stem-cell-specific markers have been described, although some of them turned out to be not as specific as it was originally proposed. In this study, we sought to search for a specific stem cell marker that would ...
Lamperti Elena - - 2011
PURPOSE: Despite advances in therapies that offer improved survival rates, clinical course of brain tumours leads to a progressive functional deterioration in patients with modifications in their psychological reaction to the disease. Patients with brain tumours are rarely assessed for quality of life and psychological variables, and even fewer studies ...
Macé Emilie - - 2011
We present functional ultrasound (fUS), a method for imaging transient changes in blood volume in the whole brain at better spatiotemporal resolution than with other functional brain imaging modalities. fUS uses plane-wave illumination at high frame rate and can measure blood volumes in smaller vessels than previous ultrasound methods. fUS ...
Koyama Junko - - 2011
A new method for simultaneous determination of histamine and prostaglandin D(2) (PGD(2)) by liquid chromatography-electrospray ionization tandem mass spectrometry operated in positive and negative ionization switching modes was developed and validated without a previous derivatization step. This method was used to measure histamine and PGD(2) release following degranulation of KU812 ...
Cleary Michelle - - 2011
Aims and objectives.  To determine clinical mental health nurses' views and preferences about continuing professional development. Background.  Participation in continuing professional development is now expected for nurse and midwifery registration. However, it is unclear how clinically based mental health nurses view continuing professional development and its relevance to career intentions. ...
Chen Ling-Ling - - 2011
Hundreds of human genes express mRNAs that contain inverted repeat sequences within their 3'-UTRs. When expressed, these sequences can be promiscuously edited by ADAR enzymes, leading to the retention of mRNAs in nuclear paraspeckles. Here we discuss how this retention system can be used to regulate gene expression.
Johannes Ludger - - 2011
The retromer complex coordinates retrograde transport of cargo proteins between endosomes and the trans-Golgi network. The sorting nexin SNX3 is required for the retrograde trafficking of Wntless, but not of other retrograde cargo proteins, revealing that the cargo specificity of retromer is provided by the sorting nexins.
Batty G David GD Department of Epidemiology and Public Health, UCL, London, UK. - - 2012
To examine gender differentials in the association between life course socioeconomic disadvantage and the risk of exceeding internationally recognised weekly and daily guidelines for 'sensible' alcohol consumption and problem drinking. A population-representative cohort study of 1,218 men and women from the west of Scotland, UK was conducted. Data on life ...
Yang Jia-Shu JS Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, and Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, - - 2011
Intracellular transport occurs through two general types of carrier, either vesicles or tubules. Coat proteins act as the core machinery that initiates vesicle formation, but the counterpart that initiates tubule formation has been unclear. Here, we find that the coat protein I (COPI) complex initially drives the formation of Golgi ...
Kwon Young-Eun YE Department of Preventive and Public Health Dentistry, School of Dentistry, Seoul National University, Seoul, - - 2011
The aim of this study was to examine whether metabolic syndrome (MS) is associated with periodontitis in a representative sample of Korean adults, who were involved in the Fourth Korea National Health and Nutrition Examination Survey (KNHANES). A total of 7178 subjects over the age of 19 years who participated ...
Ehrlich Joachim R - - 2011
INTRODUCTION: Atrial fibrillation (AF) is associated not only with inflammation but also with structural remodelling and altered endothelial activation which may contribute to clot formation, embolization and mortality. We aimed to determine the predictive value of single-time biomarker analysis for prediction of outcome in patients with AF. METHODS AND RESULTS: ...
Al-Hezaimi Khalid - - 2011
Abstract -  This experiment assessed the efficacy of the enamel matrix derivative (EMD) to regenerate cementum in vital and endodontically treated teeth with osseous dehiscence defects. Five adult female beagle dogs were used. Thirty maxillary teeth (bilateral maxillary canines and second and fourth premolars) were randomly divided into two experimental groups ...
L'huillier Ag - - 2011
OBJECTIVE: HIV-infected children have impaired antibody responses after exposure to certain antigens. Our aim was to determine whether HIV-infected children had lower varicella zoster virus (VZV) antibody levels compared with HIV-infected adults or healthy children and, if so, whether this was attributable to an impaired primary response, accelerated antibody loss, ...
Kotwicka Malgorzata - - 2011
Phosphatidylserine membrane translocation (PST) is considered to be a marker of apoptosis; however, numerous studies have reported on its role in processes not related to cell death. The purpose of the study was to investigate: (1) what is the impact of PST on the motility of spermatozoa, and (2) does ...
Senti Gabriela - - 2011
Allergen specific immunotherapy (SIT) is the only treatment of IgE mediated allergies that is causative and has a long-term effect. Classically, SIT requires numerous subcutaneous injections of the allergen during 3-5 years. Over the last decade sublingual allergen applications have established as an alternative, but treatment duration could not be shortened. ...
Khalil Hala Badr - - 2011
The canonical Gα subunit of the heterotrimeric G protein complex from wheat (Triticum aestivum), GA3, and the calcium-binding protein, Clo3, were revealed to interact both in vivo and in vitro and Clo3 was shown to enhance the GTPase activity of GA3. Clo3 is a member of the caleosin gene family ...
Ray Swatismita - - 2011
Two abiotic stress-inducible upstream regulatory sequences (URSs) from rice have been identified and functionally characterized in rice. NBS-Str1 and BLEC-Str8 genes have been identified, by analysing the transcriptome data of cold, salt and desiccation stress-treated 7-day-old rice (Oryza sativa L. var. IR64) seedling, to be preferentially responsive to desiccation and ...
Harterink Martin M Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT, Utrecht, The - - 2011
Wnt proteins are lipid-modified glycoproteins that play a central role in development, adult tissue homeostasis and disease. Secretion of Wnt proteins is mediated by the Wnt-binding protein Wntless (Wls), which transports Wnt from the Golgi network to the cell surface for release. It has recently been shown that recycling of ...
Fotheringham Diane - - 2011
Aims and objectives.  To examine how the role of the Emergency Nurse Practitioner has evolved in Scotland. Background.  In 2001, Cooper and colleagues published a report on their survey (carried out in 1998) which described the extent and nature of Emergency Nurse Practitioner services in Scotland. They described a nascent ...
De Subhajyoti S Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, - - 2011
An unstable genome is a hallmark of many cancers. It is unclear, however, whether some mutagenic features driving somatic alterations in cancer are encoded in the genome sequence and whether they can operate in a tissue-specific manner. We performed a genome-wide analysis of 663,446 DNA breakpoints associated with somatic copy-number ...
Walkley Carl R - - 2011
RNA editing by deamination of adenosine to inosine (A-to-I editing) is a physiologically important posttranscriptional mechanism that can regulate expression of genes by modifying their transcripts. A-to-I editing is mediated by adenosine deaminases acting on RNA (ADAR) that can catalytically exchange adenosines to inosines, with varying efficiency, depending on the ...
Kadhim H M - - 2011
Vibrio parahaemolyticus is a marine bacterium and some strains cause gastroenteritis in humans. Clinical isolates are thought to possess virulence factors that are absent from the majority of environmental isolates. Use of randomly amplified polymorphic DNA (RAPD)-PCR produced a unique 600 bp amplicon (band Y) in the majority of clinical isolates ...
Serr Julie - - 2011
The mechanism of adipose tissue lipolysis has not been fully elucidated. Greater understanding of this process could allow for increased feed efficiency and reduced fat in poultry. Studies in avian species may provide important insight in developing therapies for human obesity, as lipolytic pathways are highly conserved. Adipose triglyceride lipase ...
Kaaya G P - - 2011
Conidia of the entomopathogenic fungus, Metarhizium anisopliae, in oil/water formulation (1 × 10(8) conidia/ml) were sprayed at 3 weekly intervals on Rhipicephalus evertsi evertsi and Rhipicephalus (Boophilus) decoloratus ticks while feeding on Afrikana bulls grazing in paddocks for a period of 1 year. The fungus reduced the on-host tick populations by 83% 3 month after ...
Fischer Brian J BJ Group for Neural Theory, Département d'Etudes Cognitives, Ecole Normale Supérieure, Paris, France. - - 2011
The owl captures prey using sound localization. In the classical model, the owl infers sound direction from the position of greatest activity in a brain map of auditory space. However, this model fails to describe the actual behavior. Although owls accurately localize sources near the center of gaze, they systematically ...
Salamonson Yenna - - 2011
salamonson y., bourgeois s., everett b., weaver r., peters k. & jackson d. (2011) Psychometric testing of the abbreviated Clinical Learning Environment Inventory (CLEI-19). Journal of Advanced Nursing. ABSTRACT: Aim.  This paper is a report of a test of the psychometric properties of a 19-item version of the Clinical Learning Environment ...
Junker K - - 2011
Research is more important than ever for urology as a clinical specialty. The enormous advances being achieved in molecular medicine should not develop outside the realm of urology. In fact, implementing them in urology serves to guarantee the further existence of our specialty with its current clinical scope. If drug ...
Roig Miguel - - 2011
Abstract -  Root fractures occur more frequently in fully erupted permanent teeth with closed apices in which the completely formed root is solidly supported in the bone and periodontium. The consequences can be complex because of combined damage to the pulp, dentine, cementum, bone, and periodontium. Management of horizontal root fractures ...
Mott Sarah L - - 2011
Similar to biological mothers during the postpartum period, women who adopt children experience increased stress and life changes that may put them at risk for developing depression and anxiety. The purpose of the current study was to compare levels of depression and anxiety symptoms between postpartum and adoptive women and, ...
Ju Young Seok - - 2011
Massively parallel sequencing technologies have identified a broad spectrum of human genome diversity. Here we deep sequenced and correlated 18 genomes and 17 transcriptomes of unrelated Korean individuals. This has allowed us to construct a genome-wide map of common and rare variants and also identify variants formed during DNA-RNA transcription. ...
Myny Dries - - 2011
myny d., van goubergen d., gobert m., vanderwee k., van hecke a. & defloor t. (2011) Non-direct patient care factors influencing nursing workload: a review of the literature. Journal of Advanced Nursing. ABSTRACT: Aims.  The aim of this paper was to detect which non-direct patient care factors are related to nursing ...
Bonger Kimberly M KM Department of Chemical & Systems Biology, Stanford University, Stanford, California, - - 2011
The ability to rapidly regulate the functions of specific proteins in living cells is a valuable tool for biological research. Here we describe a new technique by which the degradation of a specific protein is induced by a small molecule. A protein of interest is fused to a ligand-induced degradation ...
McDonald Oliver G OG Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, - - 2011
Epithelial-to-mesenchymal transition (EMT) is an extreme example of cell plasticity that is important for normal development, injury repair and malignant progression. Widespread epigenetic reprogramming occurs during stem cell differentiation and malignant transformation, but EMT-related epigenetic reprogramming is poorly understood. Here we investigated epigenetic modifications during EMT mediated by transforming growth ...
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