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Hunter Eric J EJ National Center for Voice and Speech at the University of Utah, Salt Lake City, USA. - - 2011
Studies suggest that occupational voice users have a greater incidence of vocal issues than the general population. Women have been found to experience vocal health problems more frequently than men, regardless of their occupation. Traditionally, it has been assumed that differences in the laryngeal system are the cause of this ...
Burns Kathleen C - - 2011
This study investigated the effects of emotional expression on actual and perceived math performance. Female participants were either asked to express their emotions or given no special instructions before taking a math test under stereotype threat or no stereotype threat conditions. Participants in the emotional expression condition performed better on ...
Enciso María - - 2011
A wide variety of techniques for the preparation of sperm are currently available, of which the most commonly employed are density-gradient centrifugation (DGC) and swim-up (SUP). To date, these methods appear to be effective in selecting functional sperm for assisted reproduction techniques (ART), but they may have negative effects on ...
Wang Chun-Juan - - 2011
1. There have been many advances in stroke research and care over the past year. The aim of the present review is to highlight the significant advances that are likely to have considerable impact on the direction of future investigations and models of clinical practice. 2. In terms of the ...
Antonelli A - - 2011
Background: To our knowledge, no previous study has evaluated the effect of interferon (IFN)-γ, tumour necrosis factor (TNF)-α, or their combination on the prototype proinflammatory cytokine interleukin (IL)-6 in primary cultured fibroblasts from patients with systemic sclerosis (SSc) at an early stage of the disease. Methods: Fibroblast cultures from five ...
Nobles Christopher L CL Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza - BCM280, Houston, TX 77030, - - 2011
The element iron is essential for bacteria and plays a key role in the virulence and pathology of bacterial diseases. The largest reservoir of iron within the human body is in protoporphyrin IX, the compound commonly referred to as heme and bound by hemoglobin. For many years, the study of ...
Harris Steven M - - 2011
Objectives: Alzheimer's disease and related disorders (ADRD) pose a potential threat to the interpersonal and intimate relationships in couples. The objective of this study was to understand the lived experiences of individuals with a spouse suffering from ADRD and how this diagnosis affects intimacy within these marital relationships. Method: This ...
Jeng Fuh-Cherng FC Communication Sciences and Disorders, Ohio University, Athens, OH 45701, USA. - - 2011
Recent studies have shown that the frequency-following response (FFR) to voice pitch can be a useful method to evaluate the signal-processing mechanisms and neural plasticity in the human brainstem. The purpose of this study was to examine the quantitative properties of the FFR trends with an exponential curve-fitting model. FFR ...
Omelchenko Irina V - - 2011
The degree of aromaticity of six-membered monoheterocycles with IV-VI group heteroatoms (C(6)H(5)X, where X = SiH, GeH, N, P, As, O(+), S(+), Se(+)) was analyzed using the results of ab initio calculations at the MP2/cc-pvtz level. Values of common aromaticity indices including those based on electronic delocalization properties, structural-dynamic features ...
Sun L - - 2011
Chemotherapy has been reported to induce epithelial-mesenchymal transition (EMT) in tumor cells, which is a critical step in the process of metastasis leading to cancer spreading and treatment failure. However, the underlying mechanisms of chemotherapy-induced EMT remain unclear, and the involvement of microRNAs (miRNA) in this process is poorly understood. ...
De Cola A A IDI-IRCCS Biochemistry Laboratory, c/o Department of Experimental Medicine, University of Rome Tor Vergata, Roma, - - 2012
Replication-dependent histone gene expression is a fundamental process occurring in S-phase under the control of the cyclin-E/CDK2 complex. This process is regulated by a number of proteins, including Flice-Associated Huge Protein (FLASH) (CASP8AP2), concentrated in specific nuclear organelles known as HLBs. FLASH regulates both histone gene transcription and mRNA maturation, ...
Van Assche N - - 2011
Objectives: This study investigates the outcome of short implants additionally placed with longer implants to support a maxillary overdenture. Materials and methods: Twelve patients received six implants to support a maxillary overdenture. Only one patient still had two molars in the maxilla, while the others had no remaining teeth. The ...
Barbato Mariapaola - - 2011
Introduction. Impaired depth perception, a fundamental aspect of early visual processing, has been shown in patients with schizophrenia suggesting a disturbance to magnocellular and possibly parvocellular pathways. Despite some evidence showing visual-perceptive deficits in people with schizotypal personality traits (SPT), depth perception has not been evaluated in these subjects. Methods. ...
Ben Shabat Yael Y Department of Mechanical Engineering, Technion, Israel Institute of Technology, Haifa, - - 2012
Facial heat exchange convection coefficients were estimated from experimental data in cold and windy ambient conditions applicable to wind chill calculations. Measured facial temperature datasets, that were made available to this study, originated from 3 separate studies involving 18 male and 6 female subjects. Most of these data were for ...
Vasseur S - - 2011
p53 is a tumor suppressor that responds to various stress signals by initiating cell-cycle arrest, senescence and apoptosis. Mutations of the p53 gene are found in over 50% of human tumors, highlighting the importance of p53 in tumor suppression. Numerous studies have reported on the interactions between p53, IGF-1-AKT and ...
Zhou Rui R Department of Microbiology and Immunology, Creighton University School of Medicine, Omaha, NE, - - 2011
Mucosal surface epithelial cells are equipped with several defense mechanisms that guard against pathogens. Recent studies indicate that microRNAs (miRNAs) mediate post-transcriptional gene suppression and may be a critical component of the complex regulatory networks in epithelial immune responses. Transcription of miRNA genes in epithelial cells can be elaborately controlled ...
Hu Xiao-Fei - - 2011
Abstract Background: Matrix metalloproteinase-7 (MMP-7) may play an important role in the development of vulnerable carotid plaque. An A-to-G transition (-181A/G) in the promoter region of MMP7 is functional in vitro by altering the transcriptional activity of the gene. The aim of this study was to investigate the association between ...
Casitas Alicia - - 2011
Well-defined aryl-Cu(iii) species undergo rapid reductive elimination upon reaction with phenolates (PhO(-)), to form aryl-OPh cross-coupling products. Kinetic studies show that the reaction follows a different mechanistic pathway compared to the reaction with phenols. The pH active cyclized pincer-like ligand undergoes an initial amine deprotonation that triggers a faster reactivity ...
Duveau Venceslas V Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, - - 2011
GABAergic transmission regulates adult neurogenesis by exerting negative feedback on cell proliferation and enabling dendrite formation and outgrowth. Further, GABAergic synapses target differentiating dentate gyrus granule cells prior to formation of glutamatergic connections. GABA(A) receptors (GABA(A) Rs) mediating tonic (extrasynaptic) and phasic (synaptic) transmission are molecularly and functionally distinct, but ...
Faucher C - - 2012
We report the first randomized study comparing early hospital discharge with standard hospital-based follow-up after high-dose chemotherapy (HDCT) and PBSCT. Patients aged 18-65 years, with an indication of PBSCT for non-leukemic malignant diseases were randomly assigned between two arms. Arm A consisted of early hospital discharge (HDCT during hospitalization, discharge ...
Furusawa Gou - - 2011
Myxococcus xanthus can vary its phenotype or 'phase' to produce colonies that contain predominantly yellow or tan cells that differ greatly in their abilities to swarm, survive and develop. Yellow variants are proficient at swarming (++) and tend to lyse in liquid during stationary phase. In contrast, tan variants are ...
Dentali F - - 2011
Many studies showed that the occurrence of cardiovascular and cerebrovascular events exhibits a seasonal and monthly variation. Evidences of a seasonal and monthly variation in the incidence of venous thromboembolism (VTE) are more conflicting. We conducted a systematic review and a meta-analysis of the literature to assess the presence of ...
Li Jiaye - - 2011
The preparation of a series of extremely bulky secondary amines, Ar*N(H)SiR(3) (Ar* = C(6)H(2){C(H)Ph(2)}(2)Me-2,6,4; R(3) = Me(3), MePh(2) or Ph(3)) is described. Their deprotonation with either LiBu(n), NaH or KH yields alkali metal amide complexes, several monomeric examples of which, [Li(L){N(SiMe(3))(Ar*)}] (L = OEt(2) or THF), [Na(THF)(3){N(SiMe(3))(Ar*)}] and [K(OEt(2)){N(SiPh(3))(Ar*)], have ...
Mor I - - 2011
Death-associated protein kinase (DAPk), a multi-domain serine/threonine kinase, regulates numerous cell death mechanisms and harbors tumor suppressor functions. In this study, we report that DAPk directly binds and functionally activates pyruvate kinase M2 (PKM2), a key glycolytic enzyme, which contributes to the regulation of cancer cell metabolism. PKM2 was identified ...
Hegerl Ulrich - - 2011
Abstract Objectives. This study tested the hypothesis that patients with depression show less and later declines into lower EEG vigilance stages (different global functional brain states) under resting conditions than healthy controls, as proposed by the vigilance theory of affective disorders. Methods. Thirty patients with Major Depressive Disorder (19 female; ...
Abhyankar S - - 2011
Autologous hematopoietic stem cell (HSC) transplant is an effective treatment for patients with hematological malignancies. Unfortunately, 15-30% of patients fail to mobilize a sufficient number of HSCs for the transplant. Plerixafor is now used as a salvage mobilization regimen, with good success. We describe here a risk-based approach for the ...
Xing F F Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, - - 2012
Identifying the spectrum of genetic alterations that cooperate with critical oncogenes to promote transformation provides a foundation for understanding the diversity of clinical phenotypes observed in human cancers. Here, we performed integrated analyses to identify genomic alterations that co-occur with oncogenic BRAF in melanoma and abrogate cellular dependence upon this ...
Toldi Gergely - - 2011
Abstract Background: Preeclampsia is characterized by a maternal systemic inflammatory response and the impairment of maternal immune tolerance present in healthy pregnancy. Soluble urokinase plasminogen activator receptor (suPAR) is a biomarker increasingly used for the monitoring of systemic inflammation. We aimed to assess the levels of suPAR and other markers ...
Sherman Allen C - - 2011
Personal meaning is thought to serve as an important resource among individuals adapting to the demands of illness. However, some work in this area has been marked by vague conceptualization, or use of assessment instruments that are confounded by well-being. This investigation evaluated relationships between psychosocial and physical outcomes and ...
Carilho Rita - - 2011
Abstract In amyotrophic lateral sclerosis (ALS), respiratory muscle weakness causes ventilatory insufficiency and tissue hypoxia, which induces a number of metabolic pathways, and in particular increases erythropoietin (EPO) synthesis. EPO is a glycoprotein with neuroprotective properties that stimulates erythropoiesis. Here, EPO plasma level in a large population of ALS patients, ...
Zhang Yuanfu - - 2011
We report herein a label-free and sensitive fluorescent method for detection of thrombin using a G-quadruplex-based DNAzyme as the sensing platform. The thrombin-binding aptamer (TBA) is able to bind hemin to form the G-quadruplex-based DNAzyme, and thrombin can significantly enhance the activity of the G-quadruplex-based DNAzyme. The G-quadruplex-based DNAzyme is ...
Bertrand J - - 2011
Therapeutic resistance of acute myeloid leukemia stem cells, enriched in the CD34(+)38(-)123(+) progenitor population, is supported by extrinsic factors such as the bone marrow niche. Here, we report that when adherent onto fibronectin or osteoblast components, CD34(+)38(-)123(+) progenitors survive through an integrin-dependent activation of glycogen synthase kinase 3β (GSK3β) by ...
Kristensen Billy B - - 2011
Objective. To evaluate the analgesic effect of high-volume infiltration analgesia in urogenital prolapse surgery, along with a detailed description of the infiltration technique. Design. A randomized, double-blind, placebo-controlled study following the CONSORT criteria. Setting. A university hospital. Patients. 48 patients undergoing posterior wall repair and perineorraphy. Methods. Patients received high-volume ...
Chao A - - 2011
MicroRNAs (miRNAs) play important roles in tumorigenesis by regulating oncogenes and tumor-suppressor genes. In this study, miR-187 and miR-200a were found to be expressed at higher levels in ovarian cancers than in benign tumors. In patients with ovarian cancer, however, higher levels of miR-187 and miR-200a expression were paradoxically associated ...
Mockus Danyte S - - 2011
To examine whether dietary self-monitoring is related to weight loss in overweight children and whether perceived social support or dietary self-efficacy affects this relation. Design. Longitudinal, behavioral intervention study. The study population included 153 children, aged 7-12 years, with daily food records from a 20-week weight loss program in San ...
Harris Adam J L - - 2011
Adults and children have recently been shown to prefer guessing the outcome of a die roll after the die has been rolled (but remained out of sight) rather than before it has been rolled. This result is contrary to the predictions of the competence hypothesis (Heath & Tversky, 1991 ), ...
Gumus Seyfettin - - 2011
Abstract Aim. To investigate serum prolidase activity (SPA) in patients with pulmonary tuberculosis (PTB). Material and methods. Twenty-nine PTB patients and 32 controls were included in the study. PTB patients (cavitary and non-cavitary) and controls were compared in terms of mean SPA. Correlations were evaluated between SPA and acute phase ...
Xiang Xiao-Guo - - 2011
Orchidaceae is one of the largest families of flowering plants. Many species of orchid are endangered, and all species are included in Conventions on International Trade of Endangered Species of Fauna and Flora (CITES) I and II, but it is very difficult to identify orchid species, even those with fertile ...
Ormrod John - - 2011
Introduction. People with delusional beliefs "jump to conclusions" (JTC). This finding is well replicated. However, there is only limited exploration of the factors that might lead a person to JTC. The aim of the present study was to explore the contribution of working memory processes (WM) and IQ to hasty ...
Ran Ying-Fen - - 2011
The explorative coordination chemistry of the bridging ligand TTF-PPB is presented. Its strong binding ability to Co(ii) and then to Ni(ii) or Cu(ii) in the presence of hexafluoroacetylacetonate (hfac(-)), forming new mono- and dinuclear complexes 1-3, is described. X-ray crystallographic studies have been conducted in the case of the free ...
Brion A - - 2011
The relevance of high-dose chemotherapy followed by auto-SCT in CLL remains to be defined. The aim of the prospective, randomized, GOELAMS LLC 98 trial was to compare two strategies in previously untreated CLL patients aged <60 years. Conventional chemotherapy (Arm A) consisted of six monthly courses of CHOP followed by ...
Omideyi Adekunbi Kehinde - - 2011
Despite widespread awareness of and access to modern contraception, high rates of unwanted pregnancies and abortions still persist in many parts of the world, even where abortion is legally restricted. This article explores perspectives on contraception and abortion, contraceptive decision-making within relationships, and the management of unplanned pregnancies. It presents ...
Sava Gianni - - 2011
In our Dalton Transactions Perspective article entitled, 'Metal-based antitumour drugs in the post genomic era', (Dalton Trans., 2006, 1929-1933) we discussed metal-based drugs in light of past decades of research. We concluded that the post-genomic era would dictate a change in the direction of the field with knowledge of the ...
D'Hondt Allison - - 2011
d'hondt a., kaasalainen s., prentice d. & schindel martin l. (2011) Bathing residents with dementia in long-term care: critical incidents described by personal support workers. International Journal of Older People Nursing doi: 10.1111/j.1748-3743.2011.00283.x Aim and objective.  The aim of this study was to describe and gain insight into the critical incidents ...
Page Michael J - - 2011
Thermolysis of [Ru(PPh(3))(dppe)(CO)HCl] (dppe = 1,2-bis(diphenylphosphino)ethane) with the N-heterocyclic carbenes I(i)Pr(2)Me(2) (1,3-diisopropyl-4,5-dimethyl-imidazol-2-ylidene), IEt(2)Me(2) (1,3-diethyl-4,5-dimethyl-imidazol-2-ylidene) or ICy (1,3-dicyclohexylimidazol-2-ylidene) gave the cyclometallated carbene complexes [Ru(NHC)'(dppe)(CO)H] (NHC = I(i)Pr(2)Me(2), 4; IEt(2)Me(2), 5; ICy, 6). Dissolution of 4 in CH(2)Cl(2) or CHCl(3) gave the trans-Cl-Ru-P complex [Ru(I(i)Pr(2)Me(2))'(dppe)(CO)Cl] (7), which converted over hours at room ...
Lomas Hannah - - 2011
The formation of a novel drug-delivery carrier for the controlled release of plasmid DNA that comprises layer-by-layer polymer capsules subcompartmentalized with pH-sensitive nanometer-sized polymersomes is reported. The amphiphilic diblock copolymer poly(oligoethylene glycol methacrylate)-block-poly(2-(diisopropylamino)ethyl methacrylate) forms polymersomes at physiological pH, but transitions to unimeric polymer chains upon acidification to cellular endocytic ...
Hart John S - - 2011
Diimine and diamine ligands that are unable to coordinate to a single metal favour the formation of unusual, high-nuclearity Zn chlorometallate and palladium chloride complexes.
Zink Mathias - - 2011
Perinatal exposure to alcohol (PEA) induces general developmental and specific neuropsychiatric disturbances accompanied by disturbed synaptic plasticity. Here we studied the long-term behavioral consequences of PEA and investigated glutamate transmission-related genes in a longitudinal fashion. After delivery, female Wistar rats and their pups were exposed to ethanol until postnatal day ...
Hammond J S - - 2011
BACKGROUND: Postresection liver failure (PLF) is the major cause of death following liver resection. However, there is no unified definition, the pathophysiology is understood poorly and there are few controlled trials to optimize its management. The aim of this review article is to present strategies to predict, prevent and manage ...
Marcelis K - - 2011
Objective: The impact of the implant position on the restorative outcome could justify guided surgery even for the single implants particularly in the aesthetic zone and especially when a simplified concept is available. Material and methods: Based on a plaster model, on which the soft tissues were mimicked (according to ...
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