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Akinci Ayse Cil - - 2011
The goal of this study was to determine the effectiveness of nurse-led, home-based pulmonary rehabilitation in patients with stage 3 or 4 chronic obstructive pulmonary disease (COPD), according to the Global Initiative for COPD (GOLD) staging system. The study consisted of 32 patients--a nurse-led, home-based pulmonary rehabilitation group (16) and ...
Johansen Lars Søndergaard - - 2011
The epidemiology of appendicitis seems to be changing; the proportion of complicated appendicitis cases is growing. The outcome of childhood appendectomy in Denmark has not previously been evaluated nationwide in Denmark. Data on all Danish children treated for appendicitis were obtained from the National Patient Registry. Reoperation, readmittance or length ...
Hong Min-Li - - 2011
Asthma is a chronic inflammatory disorder of airways that affects approximately 300 million adults and children worldwide. Most therapy currently uses bronchodilators and corticosteroids. Systemic side effects from chronic use of these drugs are concern. Chinese medicine (CM) has a long history of human use in China and other Asian ...
Mahmood Arif - - 2011
The distal balloon anchoring technique involves inflation of a balloon distal to or at a target lesion to facilitate equipment delivery. We report various applications of this technique to facilitate complex coronary and peripheral arterial interventions.
Luo Rong R Division of Newborn Medicine, Department of Medicine, Children's Hospital and Harvard Medical School, Boston, Massachusetts, - - 2011
Bilateral frontoparietal polymicrogyria is an autosomal recessive inherited human brain malformation with abnormal cortical lamination. The affected cortex appears to consist of numerous small gyri, with scalloping of the cortical-white matter junction. There are associated white matter, brain stem, and cerebellar changes. Affected individuals manifest mental retardation, language impairment, motor ...
O'Loughlin Ryan E RE Department of Psychiatry, University of Rochester Medical Center, Rochester, New York, USA. - - 2011
Given their prevalence and persuasive power in our culture, gender norms--commonly described as socially reinforced, learned expectations of what it means to be a man or a woman--likely contribute to sex differences in service utilization for depression. This study investigated whether sex differences in toughness, a gender-linked norm characterized by ...
Celik Ali Kutta - - 2011
Our aim was to compare the clinical, radiological and prognostic features of spontaneous spondylodiscitis secondary to tuberculosis (TS) and brucellosis (BS). This prospective study involved 41 patients diagnosed with spondylodiscitis. Of these, 18 (43.1%) had BS and 23 (56.1%) had TS. The mean age of TS patients was 52 ± ...
Liu Zhihai - - 2011
We propose an integrated fiber Michelson interferometer based on a poled hollow twin-core fiber. The Michelson interferometer can be used as an electro-optic modulator by thermal poling one core of the twin-core fiber and introducing second-order nonlinearity in the fiber. The proposed fiber Michelson interferometer is experimentally demonstrated under driving ...
Soto Marcelo A - - 2011
We experimentally investigate the benefits of a new optical pulse coding technique for long-range, meter and submeter scale Raman-based distributed temperature sensing on standard single-mode optical fibers. The proposed scheme combines a low-repetition-rate quasi-periodic pulse coding technique with the use of standard high-power fiber lasers operating at 1550 nm, allowing for ...
Paetzold S Christine - - 2011
With the increasing spread of invasive marine species and their detrimental effects on aquaculture operations globally, mitigation strategies need to be optimized to mitigate economic impacts. The efficacy of a potassium monopersulphonate triple salt based disinfectant used in the aquaculture industry (Virkon® Aquatic at 0.5-5%) was evaluated against the solitary ...
Kim Kyoung-Ah - - 2011
BACKGROUND: Donepezil is a potent inhibitor of acetylcholinesterase, an enzyme that is targeted in the treatment of Alzheimer's disease. OBJECTIVE: The purpose of this study was to compare the pharmacokinetic characteristics of orally disintegrating (test) and conventional (reference) donepezil formulations to satisfy the regulatory requirement for marketing. METHODS: A single-center ...
Karuppiah Kanchana K Department of Anesthesiology, Ohio State University, Columbus, Ohio, - - 2011
In the vasculature, nitric oxide (NO) is generated by endothelial NO synthase (eNOS) in a calcium/calmodulin-dependent reaction. In the absence of the requisite eNOS cofactor tetrahydrobiopterin (BH(4)), NADPH oxidation is uncoupled from NO generation, leading to the production of superoxide. Although this phenomenon is apparent with purified enzyme, cellular studies ...
Armstrong Philip M PM Center for Vector Biology and Zoonotic Diseases, The Connecticut Agricultural Experiment Station, New Haven, CT 06504, USA. - - 2011
West Nile virus (WNV) has become firmly established in northeastern US, reemerging every summer since its introduction into North America in 1999. To determine whether WNV overwinters locally or is reseeded annually, we examined the patterns of viral lineage persistence and replacement in Connecticut over 10 consecutive transmission seasons by ...
Lin Rong - - 2011
Biliverdin reductase A (BLVRA) is a powerful intracellular antioxidant enzyme and an antagonist to insulin-mediated glucose uptake by the cells. Increased oxidative stress and insulin-resistance (IR) are associated with increased risk for hypertension. Therefore, we hypothesized that BLVRA might be attributable to the variation of susceptibility to essential hypertension, and ...
Terme Magali - - 2011
Immunosuppressive cytokines subvert innate and adaptive immune responses during cancer progression. The inflammatory cytokine interleukin-18 (IL-18) is known to accumulate in cancer patients, but its pathophysiological role remains unclear. In this study we demonstrate that low levels of circulating IL-18, either exogenous or tumor-derived, act to suppress the NK cell ...
Hartung A - - 2011
Background: In the production of enalapril maleate tablets, the granulation process is the most crucial step. Numerous variables are known to influence the fluid bed granulation process and thus the final granule quality. In this study a novel descriptor for the nozzle parameter "air-to-liquid mass ratio" is presented. Granules manufacturing ...
Alonso Cánovas A - - 2011
BACKGROUND: Non-ergot dopamine agonists (DA) are effective treatments for Parkinson's disease (PD). A review is presented of the pharmacology, evidence of efficacy and safety profile of pramipexole, ropinirole and rotigotine, and practical recommendations are given regarding their use in clinical practice. RESULTS: Extended release formulations of pramipexole and ropinirole and ...
Gandjour Afschin - - 2011
We propose a new prize (reward) system for drug innovation which pays a price based on the value of health benefits accrued over time. Willingness to pay for a unit of health benefit is determined based on the cost-effectiveness ratio of palliative/nursing care. We solve the problem of limited information ...
Castadot Pierre - - 2011
BACKGROUND AND PURPOSE: The planning process in radiotherapy (RT) typically involves the acquisition of a unique set of CT images - and eventually of functional images - which is used for delineation of target volumes (TV) and organs at risk (OAR) and for dose calculation. Restricting the delineation and dose ...
He Yue - - 2011
The vascularized free fibula flap has become the most popular reconstruction method after mandibular resection because of adequate bone graft length and acceptance of dental implants. However, using 1 fibula bone may produce a height discrepancy between the native mandible and the grafted fibula that results in subsequent difficulty in ...
Pageau Steven C - - 2011
The stroma plays an important role in the development and progression of human diseases. Pulmonary diseases such as asthma, fibrosis and cancer are thought to be the result of altered communications between the epithelial and stromal tissue compartments. In order to study these epithelial-mesenchymal interactions, we developed a three dimensional ...
Greiter Matthias B - - 2011
Biokinetic models describing the uptake, distribution and excretion of trace elements are an essential tool in nutrition, toxicology, or internal dosimetry of radionuclides. Zirconium, especially its radioisotope (95)Zr, is relevant to radiation protection due to its production in uranium fission and neutron activation of nuclear fuel cladding material. We present ...
Ding Li L College of Science, Northwest A&F University, Yangling, Shaanxi, - - 2011
An N-terminal and C-terminal truncated recombinant α2-6-sialyltransferase cloned from Photobacterium sp. JH-ISH-224, Psp2,6ST(15-501)-His(6), was shown to be an efficient catalyst for one-pot three-enzyme synthesis of sialyl Tn (STn) antigens and derivatives containing natural and non-natural sialic acid forms.
Sadakiyo Masaaki - - 2011
One of the dominant types of interactions between host and guest molecules is hydrogen-bonding, and these interactions can work selectively for a guest molecule. Here, we demonstrate a metal-organic framework (MOF) having both hydrogen-bonding donor and acceptor sites that are quite effective for selective sorption. The MOF selectively interacts with ...
Rankin J Scott - - 2011
OBJECTIVE: Pulmonary dysfunction/multiorgan failure syndrome is an important cause of mortality and morbidity after cardiac operations. In this series, results of immune augmentation were assessed in patients experiencing pulmonary dysfunction/multiorgan failure syndrome after cardiac surgery. METHODS: Since 2002, 44 consecutive patients with primary antibiotic-refractory pulmonary dysfunction/multiorgan failure syndrome were treated ...
Du Zongjun - - 2011
Strain HQM9, an aerobic, rod-shaped marine bacterium from red algae, can produce agarases and liquefy solid plating media efficiently when agar is used as a coagulant. Here we report the draft genome sequence and the initial findings from a preliminary analysis of strain HQM9, which should be a novel species ...
Lee Yun-Kyoung - - 2011
Cyclooxygenase-2 (COX-2), the key enzyme of the conversion of arachidonic acid to prostaglandins is an important regulator of inflammation and perhaps apoptosis. Genistein is an active component of legumes and other related food associated with prevention of degenerative diseases possibly through modulating certain signaling pathways. It was investigated whether the ...
Coorevits An - - 2011
'Bacillus macroides' ATCC 12905T (= DSM 54T = LMG 18474T), isolated in 1947 from cow dung, was not included in the Approved Lists of Bacterial Names and so it lost standing in bacteriological nomenclature. Reinvestigation of the strain, including DNA-DNA relatedness experiments, revealed that 'Bacillus macroides' is genomically distinct from ...
de Souza Vinícius Pereira VP Serviço de Anestesiologia do Hospital Mater Dei, Brazil. - - 2011
Reducing the mass of local anesthetic minimizes the effects of hypotension after spinal anesthesia for cesarean section and the incidence of maternal adverse events preserving fetal well-being, but it may result in insufficient anesthesia. Hypotension associated with greater masses of subarachnoid anesthesia can be controlled by prophylactic continuous infusion of ...
Freitas-Silva Otniel - - 2011
This screening aimed to evaluate quantitatively the occurrence of fungal metabolites in Brazil nuts. Nuts were collected from Agroforest production areas in Amazon basin region. A total of 235 mycotoxins (including the most prominent ones) was screened by a multi-mycotoxin method based on HPLC-MS/MS. The recovery of metabolites by the ...
Sanverdi S Eser - - 2012
Meningiomas are mostly benign, however atypical or malignant subtypes with more aggressive clinical course and higher recurrence rates can also be seen. The purpose of this study was to determine whether histopathological subtypes of meningiomas could be assessed preoperatively using apparent diffusion coefficient (ADC) values. Conventional magnetic resonance (MR) and ...
Darbera Lys - - 2011
Mild hypothermia (32°C-34°C) exerts a potent cardioprotection in animal models of myocardial infarction. Recently, it has been proposed that this beneficial effect is related to survival signaling. We, therefore, hypothesized that the well-known cardioprotective pathways dependent on adenosine and/or opioid receptors could be the trigger of hypothermia-induced salvage. Open-chest rabbits ...
Arntsen Torill - - 2011
In preorthodontic children with Class II malocclusion and horizontal maxillary overjet, cervical column morphology was examined and related to craniofacial morphology and head posture for the first time. Two hundred thirteen children (aged 7-15 years) with a horizontal maxillary overjet of more than 6 mm were divided into 2 groups ...
Taneja Vipul - - 2011
The phenotypic shift of smooth muscle cells (SMCs) from contractile to synthetic phenotype after endovascular stenting has been deemed to be the predominant cause of restenosis. Although substrate topography has been shown to affect SMC response for a variety of polymers, effect of topography on phenotype of SMCs has not ...
Puri Basant K - - 2011
Evaluation of: Ho BC, Andreasen NC, Ziebell S, Pierson R, Magnotta V. Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia. Arch. Gen. Psychiatry 68(2), 128-137 (2011). Schizophrenia is associated with progressive brain changes, including progressive brain tissue decreases and lateral ventricular volume increases for up to ...
Hankinson Todd C - - 2011
Object The current management paradigm for children with newly diagnosed diffuse intrinsic pontine glioma (DIPG) is to establish a diagnosis and begin therapy based on MR imaging findings correlated with an appropriate clinical presentation, and without a tissue diagnosis. This strategy assumes that pediatric neurosurgeons and neurooncologists uniformly interpret MR ...
Shi Jian-Ping - - 2011
To evaluate the synergistic effects of tetrandrine (TET) on the antifungal activity of topical ketoconazole (KCZ) in the treatment of dermatophytoses. The minimum inhibitory concentrations (MICs) for KCZ and combined KCZ and TET were compared in vitro. A randomized, double-blind trial was conducted among 97 patients with dermatophytoses who were ...
Okura Hiroyuki - - 2011
Presence of allergy to iodinated contrast may prevent percutaneous coronary intervention (PCI) to be performed. We present a 76-year-old male with a history of allergic reaction to iodinated contrast who successfully underwent intravascular ultrasound (IVUS) and a Doppler guidewire-guided PCI. Stent size was determined based on IVUS. After PCI, stent ...
Dhamija Radhika - - 2011
Chromosomal abnormalities involving deletions and duplications are known to cause severe developmental disorders, including mental retardation, dysmorphism, and seizures, in children. As the technique of array-based comparative genomic hybridization is being applied more frequently in the diagnostic evaluation of children with developmental disorders, novel pathologic chromosomal abnormalities are being identified. ...
Parashari Umesh C - - 2011
Primary renal hydatid disease which involves any other organ is extremely rare. Cystic rupture into the pelvicalyceal system, causing hydatiduria, is pathognomonic of renal hydatidosis, although it is usually microscopic and is seen in only 10-20% of renal hydatidosis cases. Gross hydaturia is uncommon but is present in the case ...
Gillard Frédéric - - 2011
A design of a miniaturized stationary Fourier transform IR spectrometer has been developed that produces a two-dimensional interferogram. The latter is disturbed by effects like parasitic interferences or disparities in the cutoff wavelength of the pixels. Thus, a simple Fourier transform cannot be used to estimate the spectrum of the ...
Hwang Taek Yong - - 2011
In this Letter, we generate laser-induced periodic surface structures (LIPSSs) on platinum following femtosecond laser pulse irradiation. For the first time to our knowledge, we study the morphological profile of LIPSSs over a broad incident angular range, and find that the morphological profile of LIPSSs depends significantly on the incident ...
Mystakidou Kyriaki - - 2011
OBJECTIVE: The study aimed to assess the psychometric properties of the Cancer Locus of Control (CLOC) scale on a Greek sample of advanced cancer patients. METHODS: The scale was translated with the forward-backward procedure to Greek. The CLOC scale was administered to 140 advanced cancer patients. It was administered twice, ...
Amirian E Susan ES Dan L. Duncan Cancer Center, The University of Texas M D Anderson Cancer Center, Houston, Texas, - - 2011
Despite extensive research on the topic, glioma etiology remains largely unknown. Exploration of potential interactions between single-nucleotide polymorphisms (SNP) of immune genes is a promising new area of glioma research. The case-only study design is a powerful and efficient design for exploring possible multiplicative interactions between factors that are independent ...
Lim Pei Nie - - 2011
BACKGROUND: Soybean (Glycine max L.) is one the most commonly consumed legumes worldwide, with 200 million metric tons produced per year. However, the inedible soy husk would usually be removed during the process and the continuous generation of soybean husk may represent a major disposal problem for soybean processing industries. ...
Ribeiro Cláudia - - 2011
Many environmental pollutants can exert adverse effects on exposed organisms, including fish, leading to disruption of the endocrine system. Enzymes involved in the sex steroid biosynthesis are potential targets for the toxic action of pollutants. In this context, we investigated the hypothesis that selected estrogenic chemicals-the pharmaceutical estrogen ethinylestradiol (EE2), ...
Yang Bing-Fen - - 2011
AIM: To prepare the monoclonal antibodies associated with hepatocellular carcinoma (HCC) for diagnosis. METHODS: 3 BALB/c mice were immunized with high metastasis characteristic HCC cells (HCCLM-6). The splenocytes from the immunized mice were fused with murine myeloma cells (Sp2/0). The hybridoma cells were screened by ELISA after coating with the ...
Ding Chen-Guang - - 2011
AIM: To explore the effect of rapamycin (RPM) on the expression of B and T lymphocyte attenuate (BTLA) on human peripheral blood T lymphocytes, providing a experimental basis for application of RPM to organ transplantation and autoimmune diseases. METHODS: Human peripheral blood mononuclear cells were isolated by Ficoll density gradient ...
Simmons Julian G - - 2011
BACKGROUND: Selective serotonin reuptake inhibitors (SSRIs) are utilised in the treatment of a wide range of disorders but the neuropsychological basis of their therapeutic efficacy remains unclear. In this study we examine the impact of 3weeks administration of sertraline, an SSRI, on mood and personality in a group of healthy ...
Gao Xiao-Ning - - 2011
Mutations and/or overexpression of c-Kit proto-oncogene frequently occur in subsets of acute myeloid leukemia (AML) and contribute to abnormal cell proliferation and poor outcomes. We showed that c-Kit expression was subject to post-transcriptional regulation by microRNA (miRNA)-193b. Notably, miR-193b was significantly down-regulated in the examined AML cells and its levels ...
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