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Calamai Martino - - 2011
Several models have been proposed to explain the cytotoxicity of Aβ oligomers. The structural polymorphism of the oligomers can account for the various toxic effects observed. By combining the use of conformation-specific antibodies and single particle tracking techniques we have investigated the mobility of individual Aβ1-42 oligomers on the plasma ...
Martínez León M I - - 2011
The middle aortic syndrome (MAS) is caused by stenosis of the abdominal aorta, often accompanied by concomitant stenosis of the renal or visceral arteries. Although MAS is uncommon (0.5-2%), it is an important cause of hypertension in children and adolescents. It is thought to originate in a failure of the ...
Lu╠łtke Eversloh Christian - - 2011
Two novel coronenediimide (CDI) derivatives, CDI 2 and dinaphtho-CDI 4, were synthesized via straightforward synthetic routes completing the homologous series of coronene tetracarboxdiimides, which show remarkable optical properties with absorption wavelengths ranging from 380 to 600 nm, high absorption coefficients, and high fluorescence quantum yields.
Laila Lia - - 2011
Haruan (Channa striatus) is a type of fresh water fish in Malaysia that is known to promote wound healing. Haruan water extract has been formulated in an aerosol system which can produce a film for wound dressing. As topical preparation, Haruan spray needs to be evaluated in terms of the ...
Vaish M M Department of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, - - 2012
Antibody detection is a safely applied method at the wide scale in diagnosis of visceral Leishmaniasis (VL). In order to further advance serodiagnosis, the rK28 antigen has been recently introduced as a candidate for diagnosis of VL. We evaluated the sensitivity and specificity of the rK28 antigen in a micro-ELISA ...
Andrade Austeclínio Newton Marinho AN Universidade Federal de Sergipe, Brazil. - - 2011
To assess the impact caused by stress on occupational health of anesthesiologists in Sergipe and to propose solutions to improve work conditions, quality of the service provided, and quality of life. WHOQOL-BREF questionnaire was applied; the sample size was determined by the Barbetta method; and Student t test and Analysis ...
Zizzari Philippe - - 2011
Ghrelin is a 28 amino acid acylated peptide originally isolated for its capacity to stimulate growth hormone secretion. Ghrelin is also an orexigenic and adipogenic hormone and a signal to increase locomotor activity in anticipation of a scheduled meal. Although ghrelin is thought to be up regulated during fasting, there ...
Sommers Ross - - 2011
Aim:  To evaluate for differences in amplitude integrated electroencephalogram (aEEG) recordings of infants with and without BPD. Methods:  This is a cross sectional study of infants ≤ 27 weeks at birth who did (n=17) or did not develop BPD (n=17). aEEG tracings were recorded at 36(0) -36(6) weeks post menstrual ...
Mulla Mubashir - - 2011
Background:  Papillary thyroid cancer (PTC) is a common endocrine cancer and commonly presents with lymph node metastases. The role of surgical removal of the central cervical lymph node compartment is poorly defined. There are no prospective randomised controlled trials addressing the relevance of the extent of the initial surgical approach. ...
Xu Feng F Department of Medicine, Demirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Center for Biomedical Engineering, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, - - 2011
Screening for effective therapeutic agents from millions of drug candidates is costly, time consuming, and often faces concerns due to the extensive use of animals. To improve cost effectiveness, and to minimize animal testing in pharmaceutical research, in vitro monolayer cell microarrays with multiwell plate assays have been developed. Integration ...
Barry J A - - 2011
BACKGROUND Our aim was to assess differences in anxiety and depression between women with and without (controls) polycystic ovary syndrome (PCOS). METHODS We conducted a systematic review and meta-analysis of published literature comparing women with PCOS to control groups on anxiety and depression. Electronic databases were searched up to 17 ...
Kantrowitz Joshua T JT Schizophrenia Research Center, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA. - - 2013
Schizophrenia patients show decreased ability to identify emotion based upon tone of voice (voice emotion recognition), along with deficits in basic auditory processing. Interrelationship among these measures is poorly understood. Forty-one patients with schizophrenia/schizoaffective disorder and 41 controls were asked to identify the emotional valence (happy, sad, angry, fear, or ...
Pandit Sandeep V - - 2011
The ionic mechanisms of electrical heterogeneity in the ischemic ventricular epicardium remain poorly understood. This study sought to test the hypothesis that the adenosine triphosphate (ATP)-activated K+ current (I(KATP)) plays an important role in mediating repolarization differences between the right ventricle (RV) and left ventricle (LV) during global ischemia. Electrical ...
Funk Marjorie - - 2011
Technology permeates every dimension of critical care. Bedside technology is integral to the assessment and monitoring of patients and to the provision of treatment. It also helps with access to vital information and can enhance communication. Although it offers extraordinary benefits to patients and clinicians, technology may also create problems. ...
Iijima Masahiro - - 2011
The purposes of this study were to obtain information about mechanical properties with the nanoindentation test for representative wire alloys and compare the results with conventional mechanical tests. Archwires having 0.016 × 0.022-in cross sections were obtained of 1 stainless steel, 1 cobalt-chromium-nickel, 1 beta-titanium alloy, and 2 nickel-titanium products. ...
Lambert Trevor - - 2011
The percentage of newly qualified doctors in the UK who want a career in general practice declined substantially in the 1990s. The English Department of Health expects that half of all doctors will become GPs. To report on choices for general practice made by doctors who qualified in 2000, 2002, ...
Malvy D - - 2011
Clin Microbiol Infect 2011; 17: 986-995 ABSTRACT: Human African trypanosomiasis (HAT), or sleeping sickness, is a vector-borne disease that flourishes in impoverished, rural parts of sub-Saharan Africa. It is caused by infection with the protozoan parasite Trypanosoma brucei and is transmitted by tsetse flies of the genus Glossina. The majority ...
Richardson Kathryn K Institute of Public Health, University of Cambridge, Cambridge, UK. - - 2011
In the older population, multimorbidity is common and 'best practice' may invite the prescription of multiple medications. To examine the association between polypharmacy, defined as the concurrent use of five or more prescription or nonprescription medications, and mortality in 12 423 participants aged ≥65 years representative of the older population of ...
Muroi Ai - - 2011
The aim in reporting this case was to discuss the pathophysiology and treatment issues in an infant with a giant syringobulbia associated with a right cerebellopontine angle (CPA) arachnoid cyst causing noncommunicating hydrocephalus. This 7-month-old infant presented to the hospital with a history of delayed milestones and an abnormal increase ...
Schwarz Stefanie - - 2011
Time-saving, efficient dental treatment is essential for patients in poor dental condition. This clinical report describes a systematic technique for restoration of the visibly-destroyed dentition of a long-term bulimia nervosa patient, including occlusal vertical dimension increase, with composite resin core foundations and prosthetic rehabilitation with ceramic crowns, in only a ...
Jalalzadeh Mojgan - - 2011
Introduction. The role of metabolic syndrome (MS) in hemodialysis population has not been thoroughly studied. This study aimed to determine the prevalence of MS and to identify its correlates among hemodialysis patients. Materials and Methods. This cross-sectional study was conducted on patients in a hemodialysis center. The MS was defined ...
Kalläne Matthias - - 2011
An advanced type of diffractive optical element is presented that combines the concept of the photon sieve with an off-axis, off-normal incidence reflection geometry. Compared to transmission optical elements, the signal-to-background ratio is significantly increased by separating the first from other diffraction orders without drastically reducing the size of the ...
Khoo Eng Huat - - 2011
We propose a quarter-wave plate based on nanoslits and analyze it using a semianalytical theory and simulations. The device comprises two nanoslits arranged perpendicular to one another where the phases of the fields transmitted by the nanoslits differ by λ/4. In this way, the polarization state of the incident light ...
Heuskin Stéphanie - - 2011
BACKGROUND: Optimisation of alginate formulations is described in order to develop semiochemical (E-β-farnesene and E-β-caryophyllene) slow-release devices in biological control approaches by attracting predators and parasitoids of aphids. Various formulation criteria were optimised with respect to semiochemical encapsulation capacity. Moreover, the optimised formulation was characterised by texturometry and confocal microscopy. ...
Onumpai Chatchaya - - 2011
To evaluate the fermentation properties of oligosaccharides derived from pectins and their parent polysaccharides, a 5-ml-working-volume, pH- and temperature-controlled fermentor was tested. Six pectic oligosaccharides representing specific substructures found within pectins were prepared. These consisted of oligogalacturonides (average degrees of polymerization [DP] of 5 and 9), methylated oligogalacturonides (average DP ...
Mayr Herbert - - 2011
The concept of hard and soft acids and bases (HSAB) proved to be useful for rationalizing stability constants of metal complexes. Its application to organic reactions, particularly ambident reactivity, has led to exotic blossoms. By attempting to rationalize all the observed regioselectivities by favorable soft-soft and hard-hard as well as ...
Keystone Edward C - - 2011
OBJECTIVE: To investigate the potential efficacy, safety, and tolerability of daily use of CH-1504 in patients with active rheumatoid arthritis (RA). US National Institutes of Health database no. NCT00658047. METHODS: In our phase II randomized double-blind double-dummy study, patients naive to methotrexate (MTX; n = 201) and having moderate to ...
Chang Dong-Seon - - 2011
Abstract Objectives: The patient's impression of the doctor is an important factor in a clinical consultation, and the doctor's attire also plays a great role in promoting trust and confidence in the patients. Previous studies have shown that a doctor in a white coat will appear more professional, confident, and ...
Kestle John R W JR Primary Children's Medical Center, University of Utah, Salt Lake City, Utah, USA. - - 2011
Quality improvement techniques are being implemented in many areas of medicine. In an effort to reduce the ventriculoperitoneal shunt infection rate, a standardized protocol was developed and implemented at 4 centers of the Hydrocephalus Clinical Research Network (HCRN). The protocol was developed sequentially by HCRN members using the current literature ...
Lu Ting-Li - - 2011
The objectives of this study were to prepare the amifostine polylactide-co-glycolide (PLGA) microsphere and investigate its irradiation protective to mouse through oral administration. Amifostine-loaded PLGA microsphere was formulated using a modified double emulsion-solvent evaporation technique. The microsphere particle was spherical with a mean diameter of 2.8 ± 0.1 µm. Release data of ...
van Wijnen H J - - 2011
Maps play an important role during the entire process of spatial planning and bring ecosystem services to the attention of stakeholders' negotiation more easily. As example we show the quantification of the ecosystem service 'natural attenuation of pollutants', which is a service necessary to keep the soil clean for production ...
Kawaguchi Mitsuyasu - - 2011
Nucleotide pyrophosphatases/phosphodiesterases (NPPs) are ubiquitous membrane-associated or secreted ectoenzymes that have a role in regulating extracellular nucleotide and phospholipid metabolism. Among the members of the NPP family, NPP1 and 3 act on nucleotides such as ATP, while NPP2, 6, and 7 act on phospholipids such as lysophosphatidylcholine and sphingomyelin. NPP6, ...
Bernatowicz Piotr - - 2011
The longitudinal <sup>13</sup>C and <sup>1</sup>H relaxation rates were determined in porphycene in CD<sub>2</sub>Cl<sub>2</sub> solution. These data, augmented by <sup>13</sup>C{<sup>1</sup>H} NOE enhancements were numerically analyzed in order to evaluate the rotational diffusion tensor of the molecule and the vibrational correction for the one-bond <sup>13</sup>C-<sup>1</sup>H dipolar couplings. The <sup>13</sup>C and <sup>1</sup>H relaxation ...
Corral M A - - 2011
We present the cases of two men with isolated spontaneous dissection of visceral arteries diagnosed by multidetector CT. In the first patient, dissection of the celiac trunk was associated with periarterial changes. In the second patient, dissection of the superior mesenteric artery was associated with stenosis at the root of ...
Jusufovic Mirza - - 2011
Background: Hypercoagulability leading to arterial or venous thrombosis and embolism in patients with cancer is a known phenomenon. Material and Methods: We describe a 62 year old woman with a clinical course compatible with catastrophic antiphospholipid syndrome but seronegative findings and mucinous lung cancer. The case is discussed with reference ...
Bosma Otto H - - 2011
BACKGROUND: Adherence to medication is a favourable with regard to survival after kidney, heart and liver transplantation. Little is known about adherence to medication in lung transplant recipients. To determine the prevalence of adherence and identify risk factors of non-adherence (NA) we evaluated adherence to tacrolimus in adult lung transplant ...
Pappas Katherine M - - 2011
Zymomonas mobilis ATCC 10988 is the type strain of the Z. mobilis subsp. mobilis taxon, members of which are some of the most rigorous ethanol-producing bacteria. Isolated from Agave cactus fermentations in Mexico, ATCC 10988 is one of the first Z. mobilis strains to be described and studied. Its robustness ...
Vink P - - 2011
The term comfort is often seen relating to the marketing of products like chairs, cars, clothing, hand tools and even airplane tickets, while in the scientific literature, the term discomfort shows up often, since it is used in research. Few papers explain the concept of a localized comfort experience in ...
Park Sung Bin - - 2011
To evaluate the imaging findings of mature cystic teratoma with malignant transformation (malignant teratoma) compared with the corresponding mature cystic teratoma (benign teratoma). This study enrolled 1325 patients with 12 malignant teratomas and 1313 benign teratomas. We compared the computed tomographic (CT) findings of eight malignant teratomas and 15 benign ...
Beal-Alvarez Jennifer S - - 2011
We examined acquisition of grapheme-phoneme correspondences by 4 deaf and hard-of-hearing preschoolers using instruction from a curriculum designed specifically for this population supplemented by Visual Phonics. Learning was documented through a multiple baseline across content design as well as descriptive analyses. Preschoolers who used sign language and had average to ...
Jayaraman Lakshmi L Department of Anaesthesia, MAX Superspeciality Hospital, Saket, New Delhi, - - 2011
Syringomyelia is a rare neurological condition characterized by the presence of an expansive cystic cavity in the spinal cord, resulting in several neurologic manifestations. The objective of the present report was to address the safety of general anesthesia in this group of patients. This is a 28-year old primipara with ...
Dong Le - - 2011
Objective: The accurate pathogenesis of ulcerative colitis (UC) is not yet well understood. Recently, TLR2, TLR4 and gut microbial flora have been proved as playing important roles in the process of UC. This study was to evaluate the effect of TLR2 and TLR4 monoclonal antibodies on gut microbial flora in ...
Knott L - - 2011
To examine effects of high omega-3 (n-3) polyunsaturated fatty acid (PUFA) diets on development of osteoarthritis (OA) in a spontaneous guinea pig model, and to further characterise pathogenesis in this model. Modern diets low in n-3 PUFAs have been linked with increases in inflammatory disorders, possibly including OA. However, n-3 ...
Rostène William - - 2011
Recent observations suggest that beside their role in the immune system, chemokines have important functions in the brain. There is a great line of evidence to suggest that chemokines are a unique class of neurotransmitters/neuromodulators, which regulate many biological aspects as diverse as neurodevelopment, neuroinflammation and synaptic transmission. In physiopathological ...
Shim Jin-Hyung - - 2011
Natural biomaterials such as hyaluronic acid, gelatin and collagen provide excellent environments for tissue regeneration. Furthermore, gel-state natural biomaterials are advantageous for encapsulating cells and growth factors. In cell printing technology, hydrogel which contains cells was printed directly to form three-dimensional (3D) structures for tissue or organ regeneration using various ...
Libregts Sten F - - 2011
Anemia of chronic disease (ACD) is a complication accompanying many inflammatory diseases. The pro-inflammatory cytokine IFNγ has been implicated in this form of anemia, but the underlying mechanism remains unclear. Here we describe a novel mouse model for ACD, in which enhanced CD27-mediated costimulation strongly increases the formation of IFNγ-producing ...
Bergonzi Sara - - 2011
Plants at early stages of development undergo a juvenile phase during which they are not competent to flower in response to environmental stimuli. The length of this phase varies among species and is extended in perennial plants particularly. In annuals, temporal changes in expression of microR156 (miR156), miR172, and their ...
Nguyen Ha T - - 2011
To document the prevalence of obese Mexican-Americans never advised by health professionals regarding exercise and diet, and to determine risk factors for no advice. Data came from 1787 obese Mexican-American adults (body mass index ≥30; age ≥18 years) in the Medical Expenditure Panel Survey. The survey included self-reported receipt of ...
Sobocinski Jonathan - - 2011
To compare the results of the endovascular aneurysm repair (EVAR) in patients considered as unfit for surgery in a "high volume" center with the EVAR-2 trial results. In our center, between January 2006 and December 2008, 469 endovascular aorta treatments were performed in high-risk patients. All the data were prospectively ...
Howse Jennifer H - - 2011
Unconventional settings, outside general medical practice, are an underutilised resource in the attempt to identify the large numbers of people with undiagnosed diabetes worldwide. The study investigated the feasibility of using optometry practices (opticians) as a setting for a diabetes screening service. Adults attending high street optometry practices in northern ...
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