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Zachariah R - - 2011
Among adults eligible for antiretroviral therapy (ART) in Thyolo (rural Malawi) and Kibera (Nairobi, Kenya), this study (a) reports on retention and attrition during the preparation phase and after starting ART and (b) identifies risk factors associated with attrition. 'Retention' implies being alive and on follow-up, whilst 'attrition' implies loss ...
Idrees Muhammad T - - 2011
Pleomorphic hyalinizing angiectatic tumor (PHAT) is a recently described rare entity. The tumor histogenesis is proposed to be of primitive undifferentiated mesenchyme. The tumor has a predilection for the subcutaneous soft tissue especially of lower extremity, although other locations have been well documented. We report a case of PHAT arising ...
Akbar Michael - - 2011
BACKGROUND: This study analyzed the demographic and morphologic features of rotator cuff disease in paraplegic patients who presented with or without shoulder pain. METHODS: Clinical and magnetic resonance imaging examinations of both shoulders were performed in 317 paraplegic patients. Mean age was 49 (range, 19-76) years. The level of spinal ...
Bento Allisson Freire - - 2011
Resolvins of the D series are generated from docosahexaenoic acid, which are enriched in fish oils and are believed to exert beneficial roles on diverse inflammatory disorders, including inflammatory bowel disease (IBD). In this study, we investigated the anti-inflammatory effects of the aspirin-triggered resolvin D1 (AT-RvD1), its precursor (17(R)-hydroxy docosahexaenoic ...
Caballe Anna - - 2011
The Endosomal Sorting Complex Required for Transport (ESCRT) machinery is a set of cellular protein complexes required for at least three topologically equivalent membrane scission events, namely multivesicular body (MVBs) formation, retroviral particle release and midbody abscission during cytokinesis. Recently, several studies have explored the mechanism by which the core ...
Heath-Heckman Elizabeth A C EA University of Wisconsin-Madison, 1550 Linden Drive, Madison, WI 53706, - - 2011
The light-organ symbiosis of Euprymna scolopes, the Hawaiian bobtail squid, is a useful model for the study of animal-microbe interactions. Recent analyses have demonstrated that chitin breakdown products play a role in communication between E. scolopes and its bacterial symbiont Vibrio fischeri. In this study, we sought to determine the ...
Stausberg Jürgen - - 2011
: Mortality is widely used to assess quality of hospital care. Inpatient mortality is easily available in administrative data. The use of periods other than length of stay is questionable. We compared different overlapping and disjunctive periods for the calculation of mortality associated with hospital care. : Information from public ...
Sokolic Robert R Disorders of Immunity Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, Bethesda, MD 20892, USA. - - 2011
Genetic deficiency of adenosine deaminase (ADA) can cause profound lymphopenia and result in the clinical presentation of severe combined immune deficiency (SCID). However, because of the ubiquitous expression of ADA, ADA-deficient patients often present also with nonimmunologic clinical problems, affecting the skeletal, central nervous, endocrine, and gastrointestinal systems. We now ...
Shuster Melanie Horbal - - 2011
Background A 30° head-of-bed elevation is recommended for most critically ill patients. Measuring intrabladder pressure with the patient in this position is controversial. Objective To assess the feasibility of measuring intrabladder pressure with a 30° head-of-bed elevation. Methods A prospective, randomized, and experimental study. Patients had intrabladder pressure measured first ...
Kilic Nihat - - 2011
The aims of this study were to investigate the effects of 2 force levels on the amount of relapse and to determine whether there is a relationship between the rates of tooth movement and relapse. Approximately 20-g (group I) and 60-g (group II) forces were applied to the maxillary central ...
Balanzá-Martínez Vicent - - 2011
Bipolar disorder (BD) is a severe, chronic affective disorder, associated with significant disability, morbidity and premature mortality. Omega-3 polyunsaturated fatty acids (PUFAs) play several important roles in brain development and functioning. Evidence from animal models of dietary omega-3 (n-3) PUFA deficiency suggest that these fatty acids are relevant to promote ...
Zhang Jing - - 2011
Survival times of patients with colorectal cancer (CRC) have increased over the past decade, primarily as a result of treatment with combinations of conventional cytotoxic agents. Because CRC is commonly associated with mutations in genes that control growth factor signaling, therapies are being developed to target the products of these ...
Gossman Michael S - - 2011
This research focuses on morbidity-mortality reviews and internal outcome focus studies. Definitions are provided as well as a complete discussion of the ideal parameters to consider when constructing each of these. The implementation of the design characteristics used may be of assistance to a center pursuing achievement of these requirements ...
Turner Michael S - - 2011
Object Posterior fossa cysts are usually divided into Dandy-Walker malformations, arachnoid cysts, and isolated and/or trapped fourth ventricles. Shunt placement is a mainstay treatment for decompression of these fluid collections when their expansion becomes symptomatic. Although several techniques to drain symptomatic posterior fossa cysts have been described, each method carries ...
Soleimani Alireza - - 2011
Introduction. Since the level of B-type natriuretic peptide (BNP) increases in heart failure, elevated plasma BNP concentration is used as a predictor in the diagnosis and management of heart failure. Due to the diminished renal clearance of BNP, its level is above normal in kidney failure. This study evaluated the ...
Jenkins Angela A Department of Anaesthesia, Victoria Infirmary, Glasgow, UK. - - 2011
Denial of pregnancy is an important condition that is more common than expected, with an incidence at 20 weeks gestation of approximately 1 in 475. The proportion of cases persisting until delivery is about 1 in 2500, a rate similar to that of eclampsia. Denial of pregnancy poses adverse consequences ...
Lo Yu-Lung - - 2011
An ultrahigh sensitivity polarimetric strain sensor is proposed based upon a four-layer D-shaped optical fiber and surface plasmon resonance (SPR) technology. In contrast to existing SPR-based sensors, which are based on changes in the refractive index of the overlayer, the sensor proposed in this study is based on the change ...
Bauer Jennifer B - - 2011
Twofold sila-substitution (C/Si exchange) of the clinically used RXR-selective retinoid agonist bexarotene leads to disila-bexarotene, which displays pharmacological potency similar to that of the parent carbon compound, as shown in a HeLa-cell-based RXR assay. Formal exchange of the SiCH(2) CH(2) Si group in disila-bexarotene with a SiCH(2) Si or SiOSi ...
Hamada Mohamed Sobhy - - 2011
Rhizoctonia cerealis, the causal agent of sharp eyespot on wheat, was not considered to be an important pathogen for many years. Recently, the disease has become endemic in many countries except for South America. The disease has created a new threat to world wheat production because the damage of wheat ...
Torday John - - 2011
ABSTRACT Adipocyte differentiation-related protein (ADRP) is a critically important protein that mediates lipid uptake, and is highly expressed in lung lipofibroblasts (LIFs). Triacylglycerol secreted from the pulmonary circulation and stored in lipid storage droplets is a robust hormonal-, growth factor-, and stretch-regulated precursor for surfactant phospholipid synthesis by alveolar type ...
Wu H-T - - 2011
The mechanisms regarding hepatic steatosis related to hepatic insulin resistance have been well documented. However, the agents for treatment of hepatic steatosis and insulin resistance remain poorly developed. Peroxisome proliferator-activated receptors (PPARs) are transcription factors that are responsible for the regulation of glucose and/or lipid metabolism. There are 3 distinct ...
Youn Jong-Chan - - 2011
BACKGROUND: Recent studies suggest that adiposity is associated with arterial stiffness. However, it is unclear which adipokine or what adiposity related parameters are related with the progression of arterial stiffness. We hypothesized that in hypertensive patients, initial levels of adipokines such as adiponectin and resistin are related to the progression ...
Lloyd-Evans Emyr - - 2011
Disrupted cellular Ca(2+) signaling is believed to play a role in a number of human diseases including lysosomal storage diseases (LSD). LSDs are a group of ∼50 diseases caused predominantly by mutations in lysosomal proteins that result in accumulation of macromolecules within the lysosome. We recently reported that Niemann-Pick type ...
Fitzgerald Edward F - - 2011
A study was conducted to evaluate the association between PCBs in residential indoor air and in the serum of older, long time residents of three upper Hudson River communities. Samples of indoor air and of serum were collected from 170 persons 55 to 74years of age, and analyzed for PCBs ...
Riddell Nicole - - 2011
Technical 1,2,5,6,9,10-hexabromocyclododecane (HBCD) consists largely of three diastereomers (α-, β-, and γ-HBCD) produced by the trans addition of bromine to cis,trans,trans-cyclododeca-1,5,9-triene (CDT). However, another seven diastereomers are theoretically possible and may be produced by trans addition of bromine across the double bonds of the other three isomers of 1,5,9-CDT. There ...
Ohkubo Kei - - 2011
Photooxygenation of cyclohexane by O(2) occurs efficiently under visible-light irradiation of an O(2)-saturated acetonitrile solution containing 9-mesityl-10-methylacridinium ions (Acr(+)-Mes) and HCl to yield cyclohexanone, cyclohexanol and hydrogen peroxide. The photocatalytic reaction is initiated by electron transfer from Cl(-) to the mesitylene radical cation moiety.
Xu Qing Chi - - 2011
We demonstrate a general strategy to prepare Bi(2)WO(6)/Ag/N-TiO(2) film with double visible-light-active components bridged by Ag nanoparticles as an electron shuttle, which exhibits enhanced photocatalytic activity and photoelectrochemical performance under visible light.
Zevenbergen Marcel Arie Günther - - 2011
We introduce an electrochemical ethylene sensor that employs a thin layer of ionic liquid as electrolyte. Ethylene is oxidized in a potential window starting ~600 mV before the onset of the gold working electrode oxidation, which inhibits the ethylene oxidation at high applied potential. The current amplitude and sensor response ...
Chien Shao-Ju - - 2011
OBJECTIVE: A transpulmonary arterial approach to repair type I ventricular septal defect is the standard. However, the possible adverse effect on the pulmonary valve by this technique has not been investigated. METHODS: A retrospective study reviewing type I ventricular septal defect repair from January 1991 to May 2010 was conducted. ...
Thamizhiniyan Venkatesan - - 2011
Background:  Most of the currently available oral hypoglycemic drugs for the treatment of diabetes mellitus elicit detrimental side effects. Hence search for plant derived products for the treatment of diabetes continues. Gossypin, a pentahydroxy flavone glucoside found rich in the flowers of Hibiscus vitifolius, possess many biological properties including antioxidant, anti-inflammatory and anticancer. The present ...
Fiocchi Federica - - 2011
The role of carcinoembryonic antigen (CEA), magnetic resonance imaging (MRI), and positron emission tomography (PET)-computed tomography (CT) in detection of local recurrence of colorectal cancer is evaluated in 71 patients, selected due to suspected relapse at CT follow-up. Recurrence was confirmed by histology in 18 cases and excluded in 25 ...
Nandha B - - 2011
Globally mosquito-borne lymphatic filariasis (LF) is targeted for elimination by 2020. Towards this goal, the scope of community-based vector control as a supplementary strategy to mass drug administration (MDA) was assessed through an intensive education campaign and evaluated using pre- and post-educational surveys in an intervention and comparison village in ...
Cantón Rafael - - 2011
Within a susceptible wild-type population, a small fraction of cells, even <10(-9) , is not affected when challenged by an antimicrobial agent. This subpopulation has mutations that impede antimicrobial action allowing their selection during clinical treatment. Emergence of resistance occurs in the frame of a selective compartment termed mutant selection ...
Geens Tom - - 2011
Objectives Toluene diisocyanate (TDI) is used in the manufacturing process of polyurethane (PU) foams and is a potent inducer of occupational asthma. The objective of this study was to evaluate the correlation between the exposure to total TDI (2,4- and 2,6-TDI) in air and the corresponding biomarker concentration of total ...
Oztürk Fırat - - 2011
The aim of this experimental study was to evaluate the effects of systemically applied zoledronic acid on bone regeneration in response to expansion of the sagittal suture and relapse in rats. Thirty-six male Wistar rats were divided into 3 groups. In the first and second groups, saline solution was given ...
Marine Leopoldo M - - 2011
Pulmonary sequestration is a rare congenital malformation whose origin is bronchial and arterial simultaneously and its vascularization comes from an anomalous systemic artery. Its clinical presentation includes recurrent pneumopathy in the same anatomic location of the lung and difficult to resolve or recurrent lung abscess. It is usually treated with ...
Zhang Wen - - 2011
Dialysis procedures are life-sustaining renal replacement therapies indicated for patients with limited or no kidney function. The formation of clots in the extracorporeal circuit during dialysis is an undesirable event. Anticoagulation is therefore routinely practiced in this context. Unfractionated heparin (UFH) is largely used in dialysis patients. However, except in ...
Elbabaa Samer K - - 2011
Tuberous sclerosis complex (TSC) is a genetic neurocutaneous disorder that commonly affects the CNS. The most commonly associated brain tumors include cortical tubers, subependymal nodules, and subependymal giant cell astrocytomas (SEGAs). The authors report an unusual case of recurrent meningitis due to a tuber-containing encephalocele via the posterior wall of ...
Ouyang Ba-Si - - 2011
To observe the effect of electro-acupuncture (EA) on tumor necrosis factor-α (TNF-α) and vascular endothelial growth factor (VEGF) in peripheral blood and joint synovia in patients with rheumatoid arthritis (RA) to verify the clinical efficacy of EA. Adopting randomized controlled principle, the 63 RA patients enrolled were assigned to two ...
Flaherty Michael P - - 2011
This report describes a case of an acute anterior myocardial infarction secondary to subacute stent thrombosis of a drug-eluting stent within the proximal segment of the left anterior descending artery (LAD) 5 days after percutaneous transluminal coronary angioplasty and stenting (PCI). The patient was initially managed with conventional dual-antiplatelet therapy ...
Bruwer Belinda - - 2011
This study used data from the South African Stress and Health Study (SASH) to examine both structural and attitudinal barriers to treatment initiation among South Africans with mental disorders and to investigate predictors of treatment dropout. Face-to-face interviews were conducted with 4,315 adult South Africans living in households or hostel ...
Zheng Huaibin - - 2011
We report experimental observation of three-field noise correlation between two coexisting four-wave mixing (FWM) signals and the probe signal in a coherently-prepared rubidium vapor system. The two FWM signals in a double-Λ type quasi-four-level atomic system are obtained in different directions via their respective phase-matching conditions and can be detected ...
Gibbons John G - - 2012
Aspergillus fumigatus is the most common and deadly pulmonary fungal infection worldwide. In the lung, the fungus usually forms a dense colony of filaments embedded in a polymeric extracellular matrix. To identify candidate genes involved in this biofilm (BF) growth, we used RNA-Seq to compare the transcriptomes of BF and ...
van den Borst Bram B Department of Respiratory Medicine, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center+, P.O. Box 616, 6200 MD Maastricht, The Netherlands. - - 2011
and aims Cross-sectional studies suggest that obstructive lung disease (OLD) and smoking affect lean mass and mobility. A study was undertaken to investigate whether OLD and smoking accelerate the ageing-related decline in lean mass and physical functioning. 260 patients with OLD (mean±SD forced expiratory volume in 1 s (FEV1) 63±18% ...
Saketkoo Lesley Ann - - 2011
The interstitial lung diseases (ILD) are a group of heterogeneous diseases that exert significant morbidity and mortality in connective tissue diseases (CTD). There is no consensus on measures of disease activity or therapeutic responsiveness, which hampers effective drug development and regulatory evaluation of candidate therapies. The CTD-ILD Special Interest Group ...
Oyekan Adebayo - - 2011
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors belonging to the nuclear receptor superfamily that undergo transactivation or transrepression by distinct mechanisms leading to induction or repression of expression of target genes. The PPAR family consists of three isoforms, α, γ, and ß/δ, which share similar structural organization, possess distinct ...
Hoogman Martine - - 2011
Objective: Attention deficit hyperactivity disorder (ADHD) is a highly heritable disorder. The NOS1 gene encoding nitric oxide synthase is a candidate gene for ADHD and has been previously linked with impulsivity. In the present study, the authors investigated the effect of a functional variable number of tandem repeats (VNTR) polymorphism ...
Yang Fei F Departments of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, - - 2011
VEGF receptor-2 (VEGFR-2 or kinase insert domain receptor; KDR) is a known endothelial target also expressed in NSCLC tumor cells. We investigated the association between alterations in the KDR gene and clinical outcome in patients with resected non-small-cell lung carcinoma (NSCLC; n = 248). KDR copy number gains (CNG), measured ...
Ding Xi-Xia - - 2011
AIM: To produce monoclonal antibodies (mAbs) against nonstructural 1 protein (NS1) of DENV-4 and characterization. METHODS: BALB/c mice were immunized with recombinant DENV4-NS1 protein and inactive DENV-4. Splenocytes of immunized mice were fused with myeloma cells (NS-1) to produce hybridoma cell lines, secreting anti-DENV4-NS1 protein mAbs. ELISA was used to ...
Ceccaroni Marcello - - 2011
This study estimates the incidence of vaginal cuff dehiscence resulting from different approaches to hysterectomy. This multicentric study was carried out retrospectively. We retrospectively analyzed 8635 patients; 37% underwent abdominal hysterectomy, 31.2% vaginal hysterectomy, and 31.8% laparoscopic hysterectomy. All the hysterectomies were considered, vaginal evisceration was registered and analyzed for ...
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