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Bhullar Shradha S - - 2011
Abstract Herpes simplex encephalitis (HSE) represents one of the most severe infectious diseases of the central nervous system. As effective antiviral drugs are available, early rapid and reliable diagnosis has become important. The objective of the present study was to develop a sensitive enzyme-linked immunosorbent assay (ELISA) protocol for herpes ...
Hopf Susanne - - 2011
Abstract Background: Fast and reliable glycemic control is of tremendous importance in intensive care units. Point-of-care devices used in professional care have to be precise and of low variability, and their connectivity has to outrange the abilities of home-care equivalents. In particular, the meter's efficiency should be tested not only ...
Rummasak Duangdee - - 2011
PURPOSE: To define factors that influence blood loss in bimaxillary osteotomies and the need for blood preparation at the Faculty of Dentistry, Mahidol University, Bangkok, Thailand. PATIENTS AND METHODS: We retrospectively studied 208 patients who underwent bimaxillary osteotomies during 2005 to 2009. Possible factors for intraoperative blood loss such as ...
Papafragkakis H - - 2011
Chronic viral hepatitis remains common in the hemodialysis (HD) and renal transplantation population although measures to limit spread of hepatitis infection in HD units have markedly reduced its prevalence. Our review focuses on the current management of hepatitis B and C infections in renal transplant candidates before and after renal ...
Wang Juan - - 2011
AIM: To investigate the effect of curcumol on the proliferation, apoptosis and the expression NF-κB in nasopharyngeal carcinoma cell line CNE-2. METHODS: CNE-2 cells were treated with curcumol at different concentration(12.5, 25, 50, 100 mg/L) and the control group; the effect of proliferation was detected by MTT method; the apoptosis ...
Jiang Qin - - 2011
The purpose of this study was to determine whether set gene plays a role in the tumorigenesis of human colorectal adenocarcinoma and oral squamous cell carcinoma. We used the human colon carcinoma cell line Ls174 and oral squamous cell carcinoma cell line HSC3 to evaluate the effect of set suppression ...
Santos Miguel J G - - 2011
In the present work a small-scale terrestrial ecosystem (STEM) containing a soil collected from an agricultural field in Central Portugal was used to evaluate the effects of the combination of the herbicide glyphosate and the insecticide dimethoate. Earthworms (Eisenia andrei), isopods (Porcellionides pruinosus), turnip seeds (Brassica rapa), and bait-lamina strips ...
Lorant Vincent - - 2011
Despite being a key player in the healthcare system, training and practising general practice has become less attractive in many countries and is in need of reform. To identify political priorities for improving GPs' attraction to the profession and their retention within it. Stakeholder face-to-face survey in Belgium, 2008. A ...
Gao Yaping - - 2011
The impact of the widely used herbicide atrazine on seedling growth and photosynthesis of eelgrass was determined. The long-term impact of the herbicide atrazine (1, 10 and 100μg/L) on growth of eelgrass Zostera marina (L.) seedlings, maintained in outdoor aquaria, was monitored over 4weeks. Exposure to 10μg/L atrazine resulted in ...
Kus Julianne V - - 2011
Many enteric bacteria use bile as an environmental cue to signal resistance and virulence gene expression. Microarray analysis of enterohemorrhagic Escherichia coli O157:H7 (EHEC) treated with bile salts revealed upregulation of genes for an efflux system (acrAB), a two-component signal transduction system (basRS/pmrAB), and lipid A modification (arnBCADTEF and ugd). ...
Lucchetti Giancarlo - - 2011
Scientists have been interested in the influence of religion on mortality for at least 130 years. Since this time, many debates have been held by researchers who believe or do not believe in this association. The objective of this study is to compare the impact of spirituality and religiosity (S/R) ...
Cui Lei - - 2011
A 47-year-old man presented with dull pain in the left upper abdomen for 1 year. Computed tomograph (CT) examination revealed a very large heterogeneously enhancing mass in the left kidney, measuring up to 28 cm. The mass was accompanied by several enlarged lymph nodes in the peri-aortic region. Radical nephrectomy ...
Lee Jason T - - 2011
Surging interest in the 0 + 5 integrated vascular surgery (VS) residency and successful recruitment of the top students in medical school requires early exposure to the field. We sought to determine the impact of a high-fidelity simulation-based preclinical endovascular skills course on medical student performance and ultimate career specialty ...
Badoux Xavier C XC Departments of Leukemia, University of Texas M. D. Anderson Cancer Center, Houston, TX, - - 2011
The best initial therapy for elderly patients with chronic lymphocytic leukemia (CLL) has not yet been defined. We investigated the activity of lenalidomide as initial therapy for elderly patients with CLL. Sixty patients with CLL 65 years of age and older received treatment with lenalidomide orally 5 mg daily for ...
Trent Simon S Behavioural Genetics Group, Schools of Psychology and Medicine, Cardiff University, Cardiff, - - 2012
Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental condition characterised by inattention, impulsivity and hyperactivity; it is frequently co-morbid with anxiety and conduct disorders, sleep perturbation and abnormal consummatory behaviours. Recent studies have implicated the neurosteroid-modulating enzyme steroid sulfatase (STS) as a modulator of ADHD-related endophenotypes. The effects of ...
Newton Robert L RL Pennington Biomedical Research Center, LSU System, Baton Rouge, Louisiana 70808, USA. - - 2011
To evaluate the implementation of intervention components of the Louisiana Health study, which was a multicomponent childhood obesity prevention program conducted in rural schools. Content analysis. Process evaluation assessed implementation in classrooms, gym classes, and cafeterias. Classroom teachers (n  =  232), physical education teachers (n  =  53), food service managers ...
Wallin Dina - - 2011
Computed tomographic angiography (CTA) has been established as a valid modality for the assessment of extremity vascular injury. Over the last several years at our institution, CTA has evolved as the primary diagnostic modality for penetrating extremity injuries, largely replacing diagnostic angiography. The purpose of this study was to evaluate ...
Monsivais Diane B - - 2011
The purpose of this paper was to examine published qualitative studies that explored the beliefs, values, and behaviors of patients with nonmalignant chronic pain during their interactions with the healthcare system. The findings were used as "cultural cues" to create patient-centered care. A literature review of primary qualitative studies that ...
Schilling Amy - - 2011
Because a significant proportion of Staphylococcus aureus strains as well as most coagulase-negative staphylococci are resistant to penicillin and semisynthetic beta-lactam drugs, the need for vancomycin and related antibiotics has never been greater. Effective use of vancomycin requires knowledge of dosing parameters and selection of target trough levels appropriate to ...
Takenouchi Toshiki - - 2011
A boy with genetically confirmed Alagille syndrome was incidentally found to manifest striking diffuse hyperintensity of the white matter on T(2)-weighted cranial magnetic resonance images. He never exhibited signs of hepatic encephalopathy. For his progressive liver failure, he underwent a live-donor liver transplant at age 2 years, which unexpectedly resulted ...
Gurjar Mohan - - 2011
Though both malaria and leptospirosis are frequent in the tropics, co-infections are under-recognized due to overlapping of clinical features. Here, we reviewed clinical manifestations of published co-infection along with our three cases. Out of a total of 18 patients, nine patients (50%) required ICU admission. Almost all patients had prodromal ...
Shnaiderman R - - 2011
We show that optical gap solitons can be produced with velocities down to 4% of the group velocity of light using a grating-assisted coupler, i.e., a fiber Bragg grating that is linearly coupled to a non-Bragg fiber over a finite domain. Forward- and backward-moving light pulses in the non-Bragg fiber(s) ...
Chen Ju-Ying - - 2011
FeCo/NiO half-shell arrays were fabricated based on the periodic monolayer polystyrene spheres. The two-dimensional magnetic periodic arrays form well-defined photonic crystals with pronounced stop bands. Quite interestingly, it is found that the stop bands can be tuned by an external magnetic field. The underlying mechanism is attributed to the controllable ...
Engene Niclas N Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, and the Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, - - 2012
The filamentous cyanobacterial genus Moorea gen. nov., described here under the provisions of the International Code of Botanical Nomenclature, is a cosmopolitan pan-tropical group abundant in the marine benthos. Members of the genus Moorea are photosynthetic (containing phycocyanin, phycoerythrin, allophycocyanin and chlorophyll a), but non-diazotrophic (lack heterocysts and nitrogenase reductase ...
Hammer C J - - 2011
To investigate the influence of maternal Se supply and plane of nutrition on lamb morbidity, mortality, and passive transfer of IgG, pregnant ewe lambs were used in 2 experiments with 2 x 3 factorial treatment arrangements. Supplementation of Se began at breeding and was either adequate Se (ASe, 9.5 μg/kg ...
Hubmann Georg - - 2011
Gpd1 and Gpd2 are the two isoforms of glycerol 3-phosphate dehydrogenase (GPDH), which is the rate-controlling enzyme of glycerol formation in Saccharomyces cerevisiae. The two isoenzymes play crucial roles in osmoregulation and redox balancing. Past approaches to increase ethanol yield at the cost of reduced glycerol yield have most often ...
Anfinsen Kristin - - 2011
BACKGROUND: Primary bone cancer comprises three major histological types: osteosarcoma (OS), Ewing sarcoma (ES) and chondrosarcoma (CS). Given the limited knowledge about the etiology of primary bone cancer, we undertook an age-period-cohort (APC) analysis to determine whether incidence varied by birth cohort or calendar period. The purpose was to examine ...
Correale Jorge - - 2011
Although Vitamin D is best known as a modulator of calcium homeostasis, it also has immune modulating potential. A protective effect of Vitamin D on Multiple Sclerosis (MS) is supported by the reduced risk associated with sun exposure and use of Vitamin D supplements. Moreover, high circulating levels of Vitamin ...
Chuang Hsin-Ying - - 2011
BACKGROUND: Persistent activation of hepatic stellate cells (HSC-T6) has been known to cause liver fibrosis. In this study, our objective was to investigate the effects of chebulagic acid and chebulinic acid, two hydrolysable tannins of tropical almond (Terminalia chebula) fruits, on collagen synthesis and signal transduction in transforming growth factor-β1-stimulated ...
Shahabadi Nahid - - 2011
One approach to accelerate the availability of new cancer drugs is to test drugs approved for other conditions as anticancer agents. In recent years, some researchers have shown that antiviral drugs, such as ritonavir, saquinavir, and nelfinavir, inhibit the growth of over 60 cancer cell lines derived from nine different ...
Lin Ning - - 2011
Neoplastic meningitis (NM) is a debilitating and increasingly frequent neurological complication of cancer characterized by infiltration of tumor cells into the leptomeninges and the subarachnoid space. Although NM is rarely curable, combined intrathecal chemotherapy and focal radiation can improve disease-related symptoms and survival. Hydrocephalus occurs in a significant proportion of ...
Zhang Huina H Spine Research Laboratory, Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan, - - 2011
In this study, the authors' goal was to investigate the long-term progression of disc degeneration and the participating mechanisms induced by needle puncture in a rat caudal disc model. The C5-6 and C7-8 intervertebral discs of the caudal spine in rats were stabbed laterally using 21-gauge hypodermic needles to a ...
Kraev Alexander I - - 2011
Fungal arterial infections are well-described entities resulting in direct invasion of the arterial wall or embolic occlusion of small and medium-sized arteries. However, acute occlusion of large vessels such as the aorta by fungal material is exceedingly rare. A 53-year-old woman presented with acute bilateral lower extremity ischemia. She had ...
He Meizi - - 2011
OBJECTIVE: This study examined students' perceptions of and suggestions for the Northern Fruit and Vegetable Program, a free, school-based fruit and vegetable snack program implemented in elementary schools in 2 regions of northern Ontario, Canada. METHODS: This was a qualitative study involving 18 focus groups with students in 11 elementary ...
Kabbour Houria - - 2011
The structure of the fully ordered α-Na3Ti2(PO4)3 NASICON compound was elucidated from high-quality single crystal data. The cation/vacancies distribution forms a 3D-homogeneous arrangement and could represent the absolute cationic ordering available in the full Na3M2(PO4)3 series, as verified in the M = Fe case. For M = Ti, the reversi-ble ...
Rigby Michael - - 2011
PURPOSE: The authors identified the need for a cross-disciplinary research view of issues to ensure an integrated citizen-centric support to achieve optimal health of individual citizens and, in particular, the role of informatics to inform and coordinate support towards integrated and holistic care. METHOD: An Exploratory Workshop was approved and ...
Xiao Pengfei - - 2011
White rot fungi can degrade a wide spectrum of recalcitrant organic pollutants, including polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated biphenyls (PCBs). In this experiment, 20 white rot fungi, belonging to genus Phlebia, were investigated for their ability to degrade dieldrin. Based on the screening results, we further investigated Phlebia acanthocystis, Phlebia ...
Biver Emmanuel - - 2011
OBJECTIVE: Osteoporosis diagnosis is based on bone mineral density (BMD) but bone remodeling is also a crucial issue. It can be assessed by bone turnover markers (BTMs). Their interest for the positive and etiological diagnosis of osteoporosis at baseline, and their predictive value for past asymptomatic vertebral fractures, were evaluated ...
Robinet Jesse J - - 2011
The hybrid density functional theory method B3LYP in combination with three systematically larger active site models has been used to investigate the substrate binding and catalytic mechanism by which Neisseria gonorrhoeae methionine sulfoxide reductase B (MsrB) reduces methionine-R-sulfoxide (Met-R-SO) to methionine. The first step in the overall mechanism is nucleophilic ...
Rouleau Dominique M - - 2011
HYPOTHESIS: We hypothesized that the radiocapitellar ratio (RCR) is a valid and reproducible method to assess radial head translation in healthy individuals and that the normal RCR of healthy individuals is 0%. MATERIALS AND METHODS: Lateral radiographs of the elbow were examined in 40 healthy patients. The measurement method of ...
Sales Christopher M - - 2011
Pseudonocardia dioxanivorans CB1190 is the first bacterium reported to be capable of growth on the environmental contaminant 1,4-dioxane and the first member of the genus Pseudonocardia for which there is an annotated genome sequence. Preliminary analysis of the genome (chromosome and three plasmids) indicates that strain CB1190 possesses several multicomponent ...
Hannam Jacqueline - - 2011
Background:  The value of acetaminophen-ibuprofen combination therapy over single therapy is uncertain in acute pediatric pain management. A model describing the interaction between these two drugs would be useful both for understanding current literature and for future study design. Methods:  Published pooled time-effect profiles in adults given combination or single ...
Schwintzer Lukas - - 2011
Spatial control of cortical actin nucleation is indispensable for proper establishment and plasticity of cell morphology. Cobl is a novel WH2 domain-based actin nucleator. The cellular coordination of Cobl's nucleation activity, however, has remained elusive. Here, we reveal that Cobl's cellular functions are dependent on syndapin. Cobl/syndapin complexes form in ...
Haerian Monir Sadat - - 2011
Objective: Recent genome-wide association studies of colorectal cancer (CRC) have identified rs6983267 G>T and rs10505477 T>C polymorphisms as key loci in the 8q24 region to be associated with CRC. In the present study, we performed a meta-analysis to determine whether these loci are risk factors for susceptibility to CRC. Materials ...
Van Dyke Kevin J - - 2011
Patient flow improvement strategies have been effective in reducing emergency department (ED) crowding, but little guidance is available on the implementation process. By using a qualitative research design, our objective was to identify common facilitators and barriers to the implementation of patient flow improvement strategies and successful approaches for mitigating ...
Brufsky Adam - - 2011
The addition of bevacizumab to paclitaxel improved progression-free survival (PFS) of patients with metastatic breast cancer (MBC). We examined the efficacy and safety of adding gemcitabine to paclitaxel/bevacizumab (PB). In this multicenter, open-label, randomized phase II trial, women with locally advanced or MBC were randomly assigned to receive paclitaxel 90 ...
Gillespie Brigid M - - 2011
Growing evidence demonstrates the link between the quality of care nurses provide, patient outcomes, and nurses' level of qualification and expertise. Little attention has been given to measuring the influence of experience and education on nurses' perceptions of their perioperative competence. To describe the influence of years of OR experience ...
Sampson Rod - - 2011
Uptake rates of influenza vaccination in young at-risk groups in primary care (UK) are known to be poor. To explore parental reasons for non-uptake of influenza vaccination in young at-risk groups. The study hypothesis was that exploration of parental reasons for non-uptake may reveal important barriers to an effective influenza ...
Kilani Ramsey K - - 2011
In the current political and economic climate, there is a desire to reduce health care costs; diagnostic imaging expenditure is one area of particular interest. The authors present a meta-analysis of the relative frequency of imaging utilization in the setting of self-referral compared with that of non-self-referral and a simulation ...
Chern Joshua J - - 2011
Object In 1998 the authors identified 5 patients with syringomyelia and no evidence of Chiari malformation Type I (CM-I). Magnetic resonance imaging of the entire neuraxis ruled out other causes of a syrinx. Ultimately, abnormal CSF flow at the foramen magnum was the suspected cause. The label "Chiari 0" was ...
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