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Choi Jung-Woo - - 2011
Aims To characterise patients with high plasminogen activator inhibitor-1 (PAI-1) expression as oral PAI-1 antagonists are currently in preclinical trials, and to determine whether the PAI-1 promoter 4G/5G polymorphism regulates PAI-1 expression in clear cell renal cell carcinoma (CCRCC). Methods PAI-1 expression was examined by immunohistochemistry in 69 CCRCC specimens. ...
Giuliano Karen K - - 2011
Purpose Clinical decision support systems are intended to improve patients' care and outcomes, particularly when such systems are present at the point of care. Protocol Watch was developed as a bedside clinical decision support system to improve clinicians' adherence to the Surviving Sepsis Campaign guidelines. This pre/post-intervention pilot study was ...
Al-Nimri Kazem S - - 2011
The aims of this research were to study the prevalence of palatally displaced maxillary canines (PDCs) in subjects with congenitally missing maxillary lateral incisor (MxI2) teeth and to assess the dental and occlusal features associated with this displacement in these subjects. The material for this study consisted of the pretreatment ...
Segev-Jacubovski Orit - - 2011
In this article, we briefly summarize the incidence and significant consequences of falls among older adults, the insufficient effectiveness of commonly used multifactorial interventions and the evidence linking falls and cognitive function. Recent pharmacologic and nonpharmacologic studies that evaluated the effects of cognitive therapy on fall risk are reviewed. The ...
Foebel Andrea D - - 2011
Background: Use of combination pharmacotherapy, including angiotensin-converting enzyme (ACE) inhibitors, angiotensin II type 1 receptor antagonists (angiotensin receptor blockers) and β-adrenoceptor antagonists (β-blockers) in the management of heart failure (HF) can reduce mortality, prevent functional decline and reduce health service use. However, these first-line therapies are underused in older populations. ...
Chern Joshua J - - 2011
Tethered cord release for a tight filum terminale is a common pediatric operation associated with low morbidity and mortality rates. While almost all would agree that keeping patients lying flat after the operation will prevent a CSF leak, the optimal period of doing so has not been determined. In this ...
Taylor William J - - 2011
To review a novel approach for constructing composite response criteria for use in chronic gout clinical trials that implements a method of multicriteria decision-making. Preliminary work with paper patient profiles led to a restricted set of core-set domains that were examined using 1000Minds(TM) by rheumatologists with an interest in gout, ...
Wakabayashi Kohei - - 2011
The process of in-stent neointimal hyperplasia (NIH) between drug-eluting stents (DES) and bare metal stents (BMS) might be different. We compared in vivo composition of in-stent NIH between DES and BMS using virtual histology-intravascular ultrasound (VH-IVUS). Volumetric VH-IVUS was used to compare in-stent NIH between 23 DES and 15 BMS ...
Ortibus Els L - - 2011
Over the past two decades, cerebral visual impairment has been recognized as a principal deficit in preterm children, and in particular those with cerebral palsy. We review the current knowledge of visual processing deficits in these children, and provide an overview of the tools for assessing cerebral visual impairment. Commercially ...
Melkumov M A - - 2011
A 24 dB gain bismuth-doped fiber amplifier at 1430 nm pumped by a 65 mW commercial laser diode at 1310 nmis reported for the first time (to our knowledge). A 3 dB bandwidth of about 40 nm, a noise figure of 6 dB, and a power conversion efficiency of about 60% are demonstrated. The temperature behavior of ...
Iwanaga Masanobu - - 2011
Eigenmodes in a typical perforated metal-insulator-metal waveguide structure have been analyzed. It is shown that the lowest eigenmode originates from a plasmonic waveguide mode between metallic layers and has net negative group velocity on the lower branch under TM polarization. The negative group velocity is directly derived from the dispersion ...
Joshi M Hiren - - 2011
An unique case of dense fouling by an acidophilic, hard rubber (polymerized rubber) degrading fungus in the acid transfer pipelines of a boron enrichment plant located at Kalpakkam, India is reported. In spite of a highly adverse environment for survival (pH 1.5, no dissolved nutrients), the fungus thrived and clogged ...
Munekage Masaya - - 2011
The pharmacokinetics of Daikenchuto (TJ-100), a pharmaceutical grade traditional Japanese medicine, were investigated in healthy Japanese volunteers after single oral administration of 2.5, 5 and 10g doses. Six ingredients [hydroxy-α-sanshool (HAS), hydroxy-β-sanshool (HBS), [6]-shogaol (6S), [10]-shogaol (10S), ginsenoside Rb(1)(GRB1) and ginsenoside Rg(1)(GRG1)] of TJ-100 were determined by using LC-MS/MS. The ...
Starck Matthieu - - 2011
A synthetic approach is developed to obtain families of luminescent lanthanide complexes and markers from a generic family of precursors built from nonadentate coordination sites. The syntheses of the precursors, based on a directed regioselective nucleophilic aromatic substitution on polyfluoropyridines, are described. Functionalisation of the synthons on the aromatic moieties ...
Peng Yen-Ming - - 2011
We here report the existence of a new cluster of adhesion-GPCRs in human immune cells. Analysis of a comprehensive immune cell transcriptome dataset indicated that expression of the closely related receptors, GPR56, GPR97, and GPR114, is associated with single lymphocyte and granulocyte subsets. Applying flow cytometric analysis with newly generated ...
Mecredy Graham - - 2011
Background The influence of the built environment on health is of contemporary societal interest. The design of streets in neighbourhood settings may contribute positively to the health of populations through increased physical activity, but it may also have injury consequences. Methods We conducted a national cross-sectional study to describe the ...
Mjoun Kamal - - 2011
BACKGROUND: The tremendous supply and low cost of distillers dried grains with solubles (DDGS) make it an attractive feedstuff for aquaculture diets. Also, several studies have shown that DDGS can be successfully fed to various finfish. The objective of this study was to evaluate the effects of inclusion rate of ...
Offman Marc N - - 2011
Recently, two studies were published that examined the structure of the acid-β-glucosidase N370S mutant, the most common mutant that causes Gaucher disease. One study used the experimental tool of X-ray crystallography, and the other utilized molecular dynamics (MD). The two studies reinforced each other through the similarities in their findings, ...
Zhai Song - - 2011
Abstract Both T-helper 17 cells (Th-17) and CD4(+)CD25(+) regulatory T cells (Tregs) play important roles in the pathogenesis of hepatitis B virus (HBV) infection. Recent studies have suggested that Th-17 and Treg cells are increased in patients with chronic hepatitis B (CHB). This study further characterizes Th-17 and Treg cells ...
Zhou Peng - - 2011
Abstract The genetic diversity of Toxoplasma gondii varies in different geographical regions. Isolates of T. gondii in South America, for example, are genetically and biologically divergent from those in North America and Europe, where the population structure is highly clonal and composed mainly of three distinct lineages known as Types ...
Kobayashi Daisuke - - 2011
Few target molecules have been identified that enable the diagnosis of lung cancer with high sensitivity and specificity, especially in the early clinical stages. Herein, we present the first evidence for mRNA overexpression of SALL4, a transcription factor essential for embryonic development and the self-renewal of embryonic stem cells, in ...
Li Qian-Ru - - 2011
AIM: To study the effects of CD74 gene on IFN-γR expression in myasthenia gravis thymic epithelial cell(TEC). METHODS: PCMV-CD74 transiently transfect to primary cultured TEC mediated with lipofectamine, the result of transfection and some autoimmune related genes such as IFN-γR were detected by real-time RT-PCR. RESULTS: Real-time quantitative RT-PCR results ...
Jankun Jerzy - - 2011
Photodynamic therapy (PDT) is a minimally invasive cancer therapy that depends on the buildup of a photosensitizing drug within targeted tissue. The photosensitizer is subsequently activated by light of a specific wavelength, resulting in destruction of the targeted tissue by free radicals or singlet oxygen. Successful treatment requires delivery of ...
Lowe Randall D - - 2011
A convenient, laboratory-scale method for the vapor deposition of dense siloxane monolayers onto oxide substrates was demonstrated. This method was studied and optimized at 110°C under reduced pressure with the vapor of tetradecyltri(deuteromethoxy)silane, (CD3O)3-Si-(CH2)13-CH3, and water from the dehydration of MgSO4•7H2O. Ellipsometric thicknesses, water contact angles, Fourier transform infrared (FTIR) ...
Bishop Sarah - - 2011
BACKGROUND: Chronic blood transfusion (CBT) is currently the standard of care for primary and secondary stroke prevention in children with sickle cell anemia (SCA). However, the effect of CBT on cerebrovascular pathology is not well known. METHODS: We reviewed children with SCA receiving CBT for abnormal transcranial Doppler (TCD) [n=12] ...
Somasundaram K - - 2011
In this work we propose two brain extraction methods (BEM) that solely depend on the brain anatomy and its intensity characteristics. Our methods are simple, unsupervised and knowledge based. Using an adaptive intensity thresholding method on the magnetic resonance images of head scans, a binary image is obtained. The binary ...
Tingaud-Sequeira Angèle - - 2011
Dietary and xenobiotic compounds may alter endocrine signaling and lipid homeostasis, thus inducing obesity. We describe a short-term assay method, the zebrafish obesogenic (ZO) test, for examining the effects of diet, drugs, and environmental contaminants, singly or in combination, on white adipose tissue (WAT) dynamics in live larvae. The ZO ...
Pauls Sandra - - 2011
The aim was to correlate dynamic magnetic resonance imaging perfusion parameters of pulmonary tumors with histological tumor classification. Eighty-six patients with lung cancer were examined. A differentiation of non-small cell lung cancer vs. small cell lung cancer was possible with the parameters tumor necrosis, maximum contrast upslope, and the time ...
Chrysohoou Christina - - 2011
BACKGROUND: The purpose of this study was to evaluate the impact of adherence to Mediterranean diet on serum uric acid (UA) levels in elderly individuals, without known cardiovascular disease. METHODS: During 2009, 281 females (75±6years old) and 257 males (75±7years old) permanent inhabitants of the island, were voluntarily enrolled. A ...
Schillinger Martin - - 2011
Intermittent claudication due to chronic femoropopliteal obstruction is a common disease, and patients are potentially severely disabled by the painful limitation of walking capacity. Despite major advances in pharmacological therapy of atherosclerosis, effective medication specifically for treatment of intermittent claudication is still not available. Training programs work well for patients ...
McConnell Paul - - 2011
A 52-year-old man with an external ventricular drain was transferred from the local neurosurgical intensive care unit to the general intensive care unit for renal replacement therapy. While the patient was in the general intensive care unit, phenytoin was accidentally administered via the external ventricular drain. Tachycardia and hypertension ensued ...
Doshi Umal H - - 2011
Skeletal open-bite malocclusion is frequently discussed in orthodontics. Diagnosis, treatment, and retention can be difficult because this malocclusion has numerous correlated etiologic factors. The earlier this malocclusion is corrected, the better the prognosis will be, especially when the problem is skeletal. This article presents a patient with a skeletal open ...
- - 2011
Abstract Our goal was to gain a better understanding of the femoral vessel anatomy as it relates to central venous cannulation. The primary objective of this study was to use bedside ultrasonography to determine the amount of exposed femoral vein at three sites corresponding to surface anatomy of the landmark-based ...
McCormack Paul L - - 2011
Ketorolac 0.45% ophthalmic solution is a topical NSAID indicated in the US for the treatment of ocular pain and inflammation following cataract surgery. In animal studies, the ocular relative bioavailability of single-dose topical ketorolac 0.45% ophthalmic solution was 2- to 3-fold higher than that of ketorolac 0.4% ophthalmic solution. In ...
Jamieson A J - - 2011
A scavenging interaction between the arrow tooth eel Synaphobranchus kaupii and the Portuguese dogfish Centroscymnus coelolepis, both ubiquitous components of fish assemblages at bathyal depths, was observed. Using a baited camera between 1297 and 2453 m in the eastern Atlantic Ocean continental slope, it was shown that despite consistently rapid ...
Geske Jeffrey B - - 2011
The left internal mammary artery (LIMA) is frequently utilized in coronary artery bypass grafting (CABG); adequate visualization of the LIMA bypass graft during diagnostic angiography is critical for determination of myocardial blood supply. We present a novel case of angiography via a left transradial approach demonstrating an occluded LIMA coronary ...
Lorenzoni Paulo José - - 2011
The most common idiopathic inflammatory myopathies in children include juvenile dermatomyositis, juvenile polymyositis, and myositis associated with another autoimmune disease (overlap myositis). Idiopathic inflammatory myopathies manifest different characteristics affecting children. Only a few investigations of childhood idiopathic inflammatory myopathies were reported, involving 27 patients. In addition, clinical findings, serum muscular ...
Becker Deborah R - - 2011
This column describes a best practice for dissemination and implementation used by the Johnson & Johnson-Dartmouth Program: a national learning collaborative among community mental health programs on supported employment. In this two-tiered learning collaborative, researchers meet regularly with mental health and vocational rehabilitation leaders in 12 states and the District ...
Liu Hai - - 2011
We numerically study the coupling of magnetic plasmon polaritons (MPPs) with Bloch surface waves (BSWs) in a system composed of a one-dimensional gold nanowire pair array lying on a periodic dielectric multilayer. At an appropriate period of the dielectric multilayer, maximum coupling takes place between the MPP and the BSW. ...
de Peralta L Grave - - 2011
We comment on a recent paper [Opt. Lett.35, 1944 (2010)]OPLEDP0146-959210.1364/OL.35.001944.
Scholz Frank - - 2011
The ultrafast charge separation at the quantum dot (QD)/molecular acceptor interface was investigated in terms of acceptor concentration and the size of the QD. Time-resolved experiments revealed that the electron transfer (ET) from the photoexcited QD to the molecular acceptor methylviologen (MV(2+) ) occurs on the fs time scale for ...
Beaudin Andrew E - - 2011
In humans, cerebrovascular responses to alterations in arterial PCO(2) and PO(2) are well documented. However, few studies have investigated human coronary vascular responses to alterations in blood gases. This study investigated the extent to which the cerebral and coronary vasculatures differ in their responses to euoxic hypercapnia and isocapnic hypoxia ...
Harris Kristina M KM Pathology Department, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. - - 2011
Distinct types of DCs are generated from monocytes using GM-CSF with IL-4 (IL4-DC) or IL-15 (IL15-DC). IL15-DCs are potent inducers of antigen-specific CD8(+) T cells, display a phenotype similar to CD14(+) cells commonly described in chronically inflamed tissues, and produce high levels of IL-1β and IL-15 in response to TLR4 ...
Derrett Sarah - - 2011
The Prospective Outcomes of Injury Study aims to identify predictors of disability following injury. Participants were selected from the entitlement claims register of New Zealand's no-fault compensation insurer, the Accident Compensation Corporation, and followed up by interview for 2 years. This report describes changes to intended Prospective Outcomes of Injury ...
Ahuja Nitin K - - 2011
The 1917-25 planning and construction at the University of Michigan of a new University Hospital, later dubbed Old Main, offers a noteworthy case study of the formal convergence of hospital and factory in early twentieth-century America. Designed by Albert Kahn, the architect responsible for Ford Motor Company's archetypal automobile plants, ...
Broekman Marike L D - - 2011
Many neurosurgeons remove their patients' hair before surgery. They claim that this practice reduces the chance of postoperative surgical site infections, and facilitates planning, attachment of the drapes, and closure. However, most patients dread this procedure. The authors performed the first systematic review on shaving before neurosurgical procedures to investigate ...
Bretschi Maren - - 2011
Integrins αvβ3 and αvβ5 are considered to play an important role in the pathogenesis of breast cancer bone metastases. This study investigates the effects of the αvβ3/αvβ5 integrin-specific inhibitor cilengitide during early metastatic bone colonization. The impact of cilengitide on the migration, invasion and proliferation of MDA-MB-231 human breast carcinoma ...
Stack Andrew G - - 2011
Mineral growth and dissolution are often treated as occurring via a single, reversible process that governs the rate of reaction. We show that multiple, distinct intermediate states can occur during both growth and dissolution. Specifically, we have used metadynamics, a method to efficiently explore the free energy landscape of a ...
Johansson Peter - - 2011
INTRODUCTION: Sleep disordered breathing (SDB), cardiovascular disease (CVD) and impaired cardiac function are common in elderly people. We investigated the association of SDB and mortality in a community dwelling elderly population, considering CVD and objectively measured impaired cardiac function have been poorly studied thus far. AIM: To investigate whether SDB ...
Li Huashou - - 2011
A 60-d greenhouse experiment was conducted to investigate the uptake and in-soil degradation of PCB-5 under single cropping and intercropping conditions involving three crop plant species: pumpkin, soybean and corn. Volatilization of PCB-5 from the soil surface was also tested. The results show that while uptake of PCB-5 by the ...
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