Total parathyroidectomy with forearm autograft (TP) and subtotal parathyroidectomy (SP) are the two widely-accepted surgical procedures for treating primary parathyroid hyperplasia. Although TP carries an increased risk of permanent hypoparathyroidism and implantation site recurrence, it is still the preferred option of some surgeons. This retrospective study's aim is to confirm ...

Empty sella syndrome is defined as a group of clinical symptoms developing as a result of herniation of the subarachnoid space within the sella, which is often associated with some degree of flattening of the pituitary gland. It is usually recognized incidentally during brain imaging studies performed for different indications, ...

Healthy volunteers' bone system investigation was performed before and after 105 days experiment in an isolated environment (MARS-105) using dual energy X-ray absorptiometry (DXA) and peripheral quantitative computed tomography (pQCT). Volumetric bone mineral density (VBMD), bone mineral density (BMD), structural parameters of radius and tibia were evaluated. There were no ...

The present paper deals with studying ofhemostasis system indices after short-term (10-11 days) space flights as well as in the course of the experiment with a 7-day "dry" immersion. The following values were determined: activated partial thromboplastin time, prothrombin time, prothrombin index, international normalized ratio (INR), thrombin time (TT); fibrinogen, ...

Non-traumatic osteonecrosis of the femoral head commonly affects young adults between the third and fifth decade of life. It is the leading cause of hip joint replacements in many Asian countries including Taiwan. The ultimate goal is the preservation of the involved hip. However, this is often challenging since early ...

We have generalized data on different breathing electrostimulation methods and have shown their merits and demerits. We have presented electrostimulation methods, the electrostimulators description, different variants of electrodes site, parameters influence. It has shown advantages breathing electrostimulation application in a medical practice.

Current standard treatment of nasopharyngeal carcinoma (NPC) is either radiotherapy alone or combined chemoradiotherapy. Surgery in the form of nasopharyngectomy is usually only offered when there is evidence of local recurrence or persistent disease. Recurrent NPC (rNPC) can be detected earlier with the utilization of Epstein-Barr virus molecular diagnosis. This ...

To investigate the effect of elevated one hour post-load plasma glucose on cardiovascular risk factors, in normal glucose tolerance (NGT) people, who are first degree relatives of type 2 diabetics. Material and methods: A cross-sectional study on 1475 NGT subjects (Arian ethnicity), who had one hour post-load plasma glucose was ...

Chromogranin A (CgA) is regarded as a major, nonspecific neuroendocrine tumour (NET) marker. The results of CgA blood concentration, however, may actually be influenced by various factors or coexisting pathological conditions. Among the factors causing a substantial increase of the blood CgA concentration are: treatment with proton-pump inhibitors or H₂-receptor ...

This review presents the advances in the molecular biology and the pathophysiology of insulin resistance with emphasis on disturbances in cellular glucose transport. New scientific information about the structure and function of glucotransporters from the GLUT4 and SLGT families underline their significance in endocrinopathies and metabolic disease pathogenesis as related ...

Gender identity disorder (GID, transsexualism) is a multidisciplinary problem of an unclear aetiology. Although the diagnosis of GID is generally established by psychiatrists, the diagnostic team always includes an endocrinologist, who is responsible for hormonal therapy. Hormonal therapy is the first step in the sex reassignment procedure and requires careful ...

Rhabdomyosarcoma of the maxillary sinus is uncommon in adults. The clinical course and appropriate treatment strategy for the disease remains to be elucidated. This article describes two adult patients with rhabdomyosarcoma of the maxillary sinus who achieved long-term survival after undergoing multimodal therapy. We also reviewed the literature regarding 23 ...

We present a case where dissociative identity disorder was effectively treated with memory retrieval psychotherapy. However, the patient's comorbid bipolar disorder contributed to the patient's instability and fortified the amnesiac barriers that exist between alter personality states in dissociative identity disorder, which made memory retrieval difficult to achieve. Implications from ...

The prion protein peptide PrP106-126 induces cell apoptosis through mechanisms involving production of intracellular reactive oxygen species. The present study investigated the effects of edaravone, a potent free radical scavenger in clinical use, on cell cytotoxicity induced by PrP106-126. Results showed that PrP106-126 decreased PC12 cell viability in a dose- ...

Bone and tendons exposure in diabetic patients requires flap reconstruction to avoid major limb amputation. However, for critical and unstable diabetic patients, revascularization and flap reconstruction may not be feasible. Skin grafts can be used in such a situation, and the purpose of this study is to evaluate this procedure ...

We've studied morphofunctional peculiarities of 47 young sportsmen-rovers. 25.6% of the young sportsmen suffered from the 1st degree arterial hypertension and 8.5% had high--normal blood pressure. Profound clinical and dynamic checkup proved that in the group of rovers with high blood pressure the indices of arterial blood pressure compared to ...

Hypothalamic dysfunction is a rarely diagnosed endocrine disorder resulting from various pathological processes affecting this brain region. It is characterized by a complex clinical manifestation, including headaches, abnormal regulation of various behaviours, abnormalities in sleeping and thermoregulation, and inappropriate secretion of many hormones. In our paper, we report the case ...

Prenatal ontogeny of human neocortex have distinctive features that make it unique. Experimental data obtained on animal models could not be easily extrapolated on human corticogenesis of middle and late gestational period. Our research was aimed at features of human cortical pyramidal neurons development within 16-26 gestational weeks. Material was ...

The author used an Internet search to locate hospitals presently practicing green policies. She also included results from a Practice Greenhealth survey. Governmental antecedents and benefits of the green movement were also included. With limited documentation of the green movement in hospitals, the primary goal was to provide a compilation ...

The role of gastrin, STH, insulin and glucose in the formation, and long-term adaptation of gastric secretion in athletes--wrestlers in the sportive and post sportive ontogeny Revealed an undulation in the age dynamics of the basal secretion of hormones and glucose in the blood. The ups and downs of different ...

The serial learning at its earlier stages that presumably involve working memory was studied in adults and children of 7-8 who were reproducing a sequences of discrete movements following the order given by a sequence of visual stimuli. In both age groups, the learning curves (latent time vs. trial number) ...

A new concept of malignant tumor growth is presented. In consists in the fact that the tumor cells in the body occur in specific immune tolerance. As s result, they form around the center of regeneration, which consists of activated towards the regeneration cells of the immune system, which support ...

In study with participation of 53 healthy men volunteers and infra-red thermograph application we obtained data confirming thermal portrait (i.e. skin temperature distribution in muscle rest conditions with minimal thermoregulatory activation) interrelations with maximal aerobic capacity (r = +0.6) and lactate level after critical muscle load (r = -0.7). Acute ...

Vitamin D is essential for the maintenance of good health, and vitamin D deficiency has been reported from many countries, including those with a lot of sunshine. This study was conducted to evaluate the vitamin D status in healthy 6- to 7-year-old children in Isfahan, Iran. Five hundred and thirteen ...

Displacement of the perceived position of the starting points relative to the objective one during the moving sound source localization is an example of the auditory perception sluggishness. The ability to localize starting and end points of sound image trajectories was studied in comparison with stationary sound image positions. Sound ...

The paper presents the study of adaptation of cardio-vascular system of children from 5 to 7 to heightened physical activity with due regard for somatic peculiarities of human organism. A careful account is given to reographic and cyclo-ergometic methods of research under the physical load of heightened power capacities 1 ...

The authors assessed the costs of hospital-acquired infections using rigorous econometric methods on publicly available data, controlling for the interdependency of length of stay and the incidence of hospital acquired infection, and estimated the cost shares of different payers. They developed a system of equations involving length of stay, incidence ...

Micropapillary variant of urothelial carcinoma (MPUC) is an uncommon variant of urothelial carcinoma with high metastatic potential. The cases reported in the literature were associated with high grade and advanced stages of the disease at presentation and had a poor prognosis. Four patients were diagnosed with MPUC at our center. ...

Disturbances in sleep are empirically associated with a number of different psychiatric disorders. In this pilot study, we examined whether four general queries about mental healthcare utilization ("Have you ever been seen by a psychiatrist?," "Have you ever been hospitalized in a psychiatric hospital?," "Have you ever been in counseling?," ...

Differences in clinical manifestation, therapeutic strategies and prognosis in men and women with acute coronary syndromes became crucial in the last decade. To present clinical characteristics of Polish women with ST-segment elevation myocardial infarction (STEMI). A total of 26,035 patients with STEMI (8989 females, 34.5%) were included between 01.06.2005 and ...

Hypertrophic obstructive cardiomyopathy (HOCM) is a rare genetic disorder characterized by left ventricular outflow tract (LVOT) obstruction. Clinical presentation ranges from absence of symptoms to sudden death. Our 60 year old patient scheduled for left modified radical mastectomy had HOCM since seventeen years with severe LVOT obstruction and mitral regurgitation. ...

A 56 year-old woman with a transplanted heart, with arterial hypertension and chronic pulmonary obstructive disease, was hospitalised because of palpitations, dyspnea, chest pain and oedema. After cyclosporine treatment she was diagnosed with renal failure, which was treated by hemodialysis. Heart rate (HR) at admission was 100, mean HR in ...

Two patients with acute myocardial infarction were admitted with unremarkable electrocardiograms, which did not reveal the location of the damage. A review of these electrocardiograms led to a suspicion of the presence of Brugada sign (BRSG), something subsequently confirmed by the administration of a sodium channel blocker. The unmasking of ...

In this report a 20-year-old male patient who had suffered tonic-clonic seizure after a single induction dose of etomidate until a bispectral index value of 60 is presented. Our best knowledge, this case is the first report of pure etomidate (with induction dose) induced generalized tonic clonic seizure proven with ...

A healthy man developed cauda equina syndrome after uneventful combined spinal and epidural anesthesia. No pre-existing neurologic disorder was recorded. There was no pain or paresthesia during needle placement, drug injection or catheter insertion. The sensory levels were improved within a few days following the deficit but little improvement on ...

Leptin is a protein produced in adipose tissue and takes part in angiogenesis and atherogenesis. Leptin is associated with development of type 2 diabetes and cardiovascular disease. Aim: To evaluate leptin concentrations in acute myocardial infarction and in the period of convalescence in patients with type 2 diabetes mellitus. Coronary ...

An individual assessment of global risk of death from cardiovascular diseases (CVD) should guide management, both life style changes and medical therapy, in order to decrease risk factors and improve prognosis. We assessed global risk in the Polish population and its relation to medical care, including blood pressure and cholesterol ...

An eroded atheromatous aorta may be a source of cholesterol crystal embolism(CCE). Embolization of atheromatous material accounts for obstruction of distal arterioles around which a foreign-body giant cell granuloma inflammatory reaction develops. The diagnosis is often delayed or un recognized because of varying or misleading clinical signs, such as renal ...

INTRODUCTION: Oral health disparities currently exist in the United States, and workforce innovations have been proposed as one strategy to address these disparities. A framework is needed to logically assess the possible role of workforce as a contributor to and to analyze workforce strategies addressing the issue of oral health ...

Recent studies suggest that preemptive analgesia may be effective in reducing postoperative pain. One physiologic explanation may be interference with the endogenous opioid response. We investigated whether long-lasting preoperative preemptive analgesia may have an effect on the hormonal stress response after total hip replacement. METHODS: 42 patients scheduled for elective ...

In the inner ear, there is considerable evidence that extracellular adenosine 5'-triphosphate (ATP) plays an important role in auditory neurotransmission as a neurotransmitter or a neuromodulator, although the potential role of adenosine signalling in the modulation of auditory neurotransmission has also been reported. The activation of ligand-gated ionotropic P2X receptors ...

BACKGROUND AND OBJECTIVE: Spinal anaesthesia for caesarean section is commonly associated with hypotension and crystalloid preload is widely recommended. Low-dose spinal appears to cause less hypotension. The aim of this study was to investigate whether the combined use of crystalloid preload and low dose spinal anaesthesia might further reduce the ...

Intercellular Ca(2+) waves can coordinate the action of large numbers of cells over significant distances. Recent work in many different systems has indicated that the release of ATP is fundamental for the propagation of most Ca(2+) waves. In the organ of hearing, the cochlea, ATP release is involved in critical ...

Horner's syndrome is a rare complication of epidural analgesia in labour. Although it is a sign of high sympathetic block, patients are usually haemodynamicaly stable. We report a case of undiagnosed Horner's syndrome complicating epidural analgesia in labour, where a standard dose of local anaesthetic was given for an emergency ...

A 14 year-old adolescent with achondroplasia and Jeune's syndrome (asphyxiating thoracic dystrophy) presented for cervical spine surgery in the prone position. Due to the need for home mechanical ventilation at night, the patient had a tracheostomy in place. With the first surgical procedure, the cuffed tracheostomy tube was left in ...

The use of a ventricular assist device (VAD) is a life-saving option for patients with heart failure refractory to conventional therapy. To assess the effect of VAD on outcomes of heart transplantation in children. Between October 1988 and June 2009, a consecutive series of 95 children (mean age 8.6 + ...

This is a case of failed intubation in a child of 15 months due to presence of laryngeal web. The airway was maintained by Cole Neonatal tube size 2 mm held at the available orifice of the glottis with maintenance of spontaneous respiration under general anesthesia till emergency tracheostomy was ...

BACKGROUND: The incidence of difficult intubations has consistently remained between 8 and 9%. We found a novel approach to the difficult intubation using a Glidescope in the awake spontaneously breathing patient. METHODS: In a difficult airway, the same approach for an awake fiberoptic intubation including excellent nerve blocks and sedation ...

Radiation to the head and neck is commonly used in the treatment of cancers. A side effect in some patients is the development of pharyngeal and or esophageal strictures. Hypopharyngeal strictures can resemble edematous larynges. If mistakenly so identified, tracheal tubes placed through these structures are unlikely to result in ...

The elimination of oral health disparities in the US will require enhancing access to oral health care services. The workshop convened in 2009 by the Institute of Medicine on the "US Oral Health Workforce in the Coming Decade" highlighted both the current workforce's failure to meet the nation's needs as ...