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Jeyachandran, Y.L. - - 2010
We report an interesting observation of minimization of bacterial attachment on titanium nitride coatings of increased thickness. DC magnetron sputtering method was used to prepare titanium nitride coatings of different thickness and the attachment of an oral bacteria Porphyromonas gingivalis was studied. With increase in thickness of the coatings the ...
Chavda, Hitesh - - 2010
The synthesis of superporous hydrogel composites (SPHCs) with carboxylmethylcellulose sodium (NaCMC) as a composite material was carried out by solution polymerization. The characterization studies were performed by measurement of apparent density, swelling studies, mechanical strength studies, and scanning electron microscopy (SEM). In double distilled water SPHCs showed tremendous increase in ...
Kanani, A. - - 2010
Recently, nanotechnology as novel interdisciplinary sciences has been introduced among all fields and gets numerous attentions, due to its unique applications. In biomedical engineering, electrospinning exhibits a lot of advantages as a nanofibers scaffolds producer, which can make appropriate resemblance in physical structure with extra cellular matrix (ECM). This is ...
Rajyalakshmi, A. - - 2010
Hematopoietic Stem Cells (HSCs) are self-renewing multipotent cells able to produce all blood cell lineages. More relevant to Hematopoietic Stem Progenitor Cells (HSPC) expansion, studies have suggested that a 3D culture microenvironment is conducive for HSPC proliferation and differentiation. The present study is an attempt to establish the conditions for ...
Wilson, Denise - - 2010
Walker, Rachael - - 2010
In New Zealand, and globally, the incidence of patients developing chronic kidney disease and entering the pre-dialysis phase is increasing at approximately 6% per year. The specialist pre-dialysis nurse plays a key role in providing care to this complex group of chronically ill people, but as yet no literature indicates ...
Prior, Patsy - - 2010
The role of practice nurses is a specific feature of the modernisation agenda of the New Zealand health service. Increasing importance is being placed on service improvement through effective decision making and enhanced clinical performance. To contribute to the development of primary health care it is crucial that nurses have ...
Mahoney, Laurie - - 2010
Public Health Nurses work with children under 18 years in schools and the community. Increasingly children are living with a parent suffering from a mental illness. Consequently Public Health Nurses are encountering more mental illness as part of their practice. The research reported in this article aimed to identify the ...
Wilson, Denise - - 2010
Van Hoeck, - - 2010
Advanced Placement Biology Lab 11 has used pillbugs as the model organism and choice chambers so that they can travel between two environments. I used cabbage white butterflies as the model organism. Each student was given their own larva and observed metamorphosis, choice behaviors of the larva, and mating behaviors ...
Digiovanni, Nick - - 2010
Students observe a tree bud from late winter until it sprouts. They learn to use dichotomous keys to identify their tree. The activity is inquiry-based; students predict when their bud will open and what it will become. Student drawings, quotes, and data are included to exemplify the process. The activity ...
Prud'homme-Genereux, Annie - - 2010
Four inquiry-based laboratories are described that introduce students to the properties of human brain cells. These experiments require no technical equipment, are inexpensive and safe, and introduce students to genuine research using neuropsychological investigations as a means of studying the properties of brain cells. Students design and conduct an experiment ...
Rife, Gwynne - - 2010
Biological research entails myriad techniques and considerations for proper experimental design and data collection. The duality of field-based research techniques and laboratory protocols makes introducing this topic to high school and undergraduate college students a challenge. Two invertebrate models that serve as wonderful tools to support an inquiry process to ...
Wells, Carrie - - 2010
The inclusion of nonscientists in biological research projects has become a useful mechanism for capturing long-term ecological data while exposing students firsthand to science and the scientific method. I have combined several existing citizen-science-based research efforts focused on Danaus plexippus, the monarch butterfly, into a comprehensive yet simple ecological lab ...
Lawson, Anton - - 2010
Heim, Werner - - 2010
Waller, Pat - - 2010
Narguizian, Paul - - 2010
Flannery, Maura - - 2010
Offner, Susan - - 2010
We present a tutorial for Cn3D, a molecular visualization program that allows students to see the tertiary structure of a protein and compare it with the primary structure of the same protein (Sayers et al., 2009). Students can also use the program to visualize two major evolutionary mechanisms: duplication and ...
Grumbine, Richard - - 2010
I describe the use of long-term data-collection projects for introductory biology or environmental science students at both the high school and the college nonmajors level. I provide specific examples of projects and information on guiding students as they learn to gather, organize, and describe data sets.
Wiener, Carlie - - 2010
This article presents a classroom activity for grades 4 to 6 based on real research from the Hawaii Institute of Marine Biology Northwestern Hawaiian Islands Research Partnership. Students learn how scientists use sound to observe and monitor marine environments. The ecological acoustic monitoring tool is used to help students practice ...
Jaskot, Bunny - - 2010
Choy, Patrick - - 2010
Embree, Joanne - - 2010
The pattern of illness associated with the first wave of the pandemic influenza A H1N1 (swine flu) in the spring and early summer of 2009 in regions of the province of Manitoba in Canada was more severe, on a population basis, than any other northern hemisphere jurisdiction outside of Mexico ...
Wei, Lan - - 2010
It is known that severe acute respiratory syndrome (SARS), a severe infectious illness, which caused an epidemic in Asia in 2003, has extensive and complex effects on human organ systems. It has been reported that the serum levels of prolactin (PRL), follicle stimulating hormone (FSH), and luteinizing hormone (LH) of ...
Zhou, Yanqiong - - 2010
Early growth response 1 (Egr-1) over-expression has been demonstrated in myocardial ischemia-reperfusion injury, which is closely associated with endothelial dysfunction. In the present study we investigated the expression of Egr-1 on cultured cardiac microvascular endothelial cells (CMECs) to help define the mechanism of myocardial ischemia- reperfusion injury. A model of ...
Wang, Q.J. - - 2010
Emodin (1,3,8-trihydroxy-6-methylanthraquinone), a natural anthraquinone derivative found in several herbal medicines, is highly active in suppressing the proliferation of various tumor cells such as breast, hepatocellular, and lung cancer cells under in vitro conditions. The mechanism of emodin-induced apoptosis in esophagus carcinoma cells, EC-109, is not completely understood. In this ...
Xie, Xiao-Yuan - - 2010
The aim of this study was to explore the histogenesis and carcinogenesis of pulmonary cancer induced by N- nitrosopiperidine (NPIP) in mice. NPIP is a form of N-nitrosamine found in tobacco smoke, which has been shown to be a genotoxic chemical as well as a mutagenic compound for inducing chromosome ...
Bao, Cuiyu - - 2010
Autologous or allogeneic mesenchymal stem cells (MSCs) have been used as one of the potential cell sources for cellular cardiomyoplasty. The adverse microenvironment in acute myocardial infarction, however, is considered a deleterious factor for MSC transplantation and cell survival. Tumor necrosis factor (TNF)-[alpha] is an inflammatory mediator produced during ischemia ...
Korteweg, Christine - - 2010
The 2009 H1N1 and H5N1 influenza viruses are newly (re-) emerged influenza A viruses (2009 A(H1N1) and A(H5N1), respectively) that have recently posed tremendous health threats in many regions worldwide. With the 2009 outbreak of H1N1 influenza A, the world witnessed the first influenza pandemic of the 21st century. The ...
Su, Meng - - 2010
The cystic fibrosis transmembrane conductance regulator (CFTR) is an important protein that acts as a chloride channel and regulates many physiological functions, including salt transport and fluid flow. Mutations in the gene encoding the CFTR protein cause cystic fibrosis. CFTR is expressed in the epithelial cells of the lungs, pancreas, ...
Fang, Shaokuan - - 2010
Venlafaxine, a novel antidepressant, inhibits serontonin and norepinephrine reuptake in the presynaptic cleft. Unlike typical selective serontonin reuptake inhibitors (SSRIs), venlafaxine may have modulatory effects on nerve terminals and neuronal plasticity. Our preliminary data found that 5 mgx[kg.sup.-1]x[d.sup.-1] of venlafaxine treatment prevented decreased synaptophysin (SYP) in the hippocampus, which results ...
Mao, Xiao - - 2010
Cleft lip and cleft palate are common congenital craniofacial birth defects in humans. Phenytoin (PHT) is a risk factor of cleft palate formation; however, the molecular mechanisms by which phenytoin exerts its teratogenic effects resulting in cleft palate remain unknown. The Satb2 gene mutation is associated with cleft palate. Satb2-deficient ...
Chen, Zhen-Guo - - 2010
The pool of ovarian primordial follicles is established during embryonic development or at birth. During the development from primordial to primary, secondary, and antral follicles, only a small portion of follicles can mature and successfully ovulate; the others are destined to degenerate through apoptotic or atretic loss. As aging advances, ...
Lu, Hui - - 2010
Chlamydia trachomatis, an obligate intracellular bacterial pathogen, is the major cause of sexually transmitted diseases worldwide. Although a variety of strategies have been taken to promote the development of a protective vaccine, no ideal vaccine has been generated so far. In this study, we transfected dendritic cells (DCs) with recombinant ...
Chen, Yong-Ru - - 2010
The sirtuin proteins are nicotinamide adenine dinucleotide dependent deacetylases and adenosine diphosphate (ADP)-ribosyl transferases associated with metabolic balance and lifespan extension. Sirtuin 1 (SIRT1) and sirtuin 4 (SIRT4) have been reported to regulate insulin secretion, but their association with the development of insulin resistance and nonalcoholic fatty liver disease remain ...
Wu, Ling-Fei - - 2010
Adenosine can exhibit cytotoxic activity in vivo and in vitro, though its mechanisms are still uncertain. In this study, we investigated the adenosine-mediated apoptotic signaling pathway and the role of NF-[kappa]B in human hepatocellular carcinoma HepG2 cells. HepG2 cells were treated with different concentrations of adenosine for 12-48 h, and ...
Peng, Mian - - 2010
The objective of this study was to examine the effects of leptin on alpha ([alpha]) 1 (I) collagen gene expression in a human osteoblast-like MG63 cell line. MG63 cells were incubated with different doses of leptin ([10.sup.-8], [10.sup.-7], and [10.sup.-6] mol x [L.sup.-1]) for 24, 48, and 72 h. [alpha]1 ...
Qi, Zongli - - 2010
The objective of this investigation was to determine if simultaneous silencing of the human papillomavirus type 18 (HPV-18) E6 and E7 oncogenes using RNA interference (RNAi) would be a potential therapeutic approach against the carcinogenic activity of this virus. Two synthetic double-stranded oligonucleotides, encoding short hairpin transcripts corresponding to HPV-18 ...
Fang, Xiao - - 2010
This study was designed to explore the effects of amiloride, a [Na.sup.+]-[H.sup.+] exchange (NHE) inhibitor, on vessel stenosis by observing the expression of NHE-1 protein in vascular smooth muscle (VSM) after balloon injury and the effects of amiloride on VSM cell proliferation, migration, and excretion of extracellular matrices (ECMs). A ...
Liang, Binhua - - 2010
There is a consensus that Gag-specific cytotoxic T lymphocyte (CTL) response plays a key role in the immune control of human immunodeficiency virus type 1 (HIV-1) infection. In this study, we analyzed all currently available gag sequences in the Los Alamos HIV sequence database and identified positive selection (PS) sites ...
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