Search Results
Results 1 - 50 of 510
1 2 3 4 5 6 7 8 9 10 >
Yazici, Yusuf - - 2012
Kinase inhibitors have now been shown to work in various types of patients and have potential to be additional weapons in our armamentarium in rheumatoid arthritis treatment. This review will go over the currently available data and discuss potential uses for these new agents.
Scher, Jose - - 2012
B cells were originally considered key mediators in the pathogenesis of rheumatoid arthritis (RA). The presence of these cells in many RA synovial tissues and the discovery of rheumatoid factor had put B cells originally at the center of disease pathogenesis. That enthusiasm vanished shortly thereafter only to resurface in ...
Woodrick, Robert - - 2012
New data published or presented in the past year has expanded our understanding of the clinical use of interleukin 6 (IL-6) inhibitors and their role in the management of rheumatoid arthritis (RA) and other rheumatic diseases. Data has become available on the use of tocilizumab (TCZ) in comparison to adalimumab, ...
Simsek, Ismail - - 2012
The use of biological agents in the treatment of rheumatoid arthritis (RA) has grown constantly since the approval of the first therapeutic monoclonal antibody against tumor necrosis factor-alpha (TNF) in 1996. While these agents transformed RA treatment, not all patients respond to these agents. Moreover, the cost of these agents ...
Pincus, Theodore - - 2012
The management of rheumatoid arthritis (RA) depends more on the patient history than most other chronic diseases. A patient questionnaire provides a uniform, quantitative, protocolized, "scientific" patient history, with documented prognostic significance for work disability and mortality in RA greater than radiographs and laboratory tests and capacity to distinguish active ...
Mease, Philip - - 2012
Some of this past year's key papers or abstracts on psoriatic arthritis (PsA) assessment and treatment are reviewed in this paper. Treatment begins with identification of the PsA patient. Several screening questionnaires have been developed to be used in dermatology and primary care settings to identify which patients with psoriasis ...
Kahn, Philip - - 2012
Juvenile idiopathic arthritis (JIA) comprises a collection of all forms of chronic arthritis in childhood with no apparent cause. JIA is the most common rheumatic disease in children, and may result in significant pain, joint deformity, and growth impairment, with persistence of active arthritis into adulthood. Prior to the mid ...
Crittenden, Daria - - 2012
From an epidemiologic view, gout is an increasingly prevalent and increasingly pressing clinical problem. This fact, together with technical advances in biology, pharmacology, and imaging techniques, have led to a decade of increasingly rapid progress in our collective understanding of gout and hyperuricemia. Here we review some of the most ...
Honig, Stephen - - 2012
The past year has been a dynamic one for clinicians and researchers with an interest in osteoporosis. This update will focus on the issue of the relationship between bisphosphonate treatment and atypical femoral fractures, highlight the advances in imaging techniques that are increasingly being studied as adjuncts to bone density ...
Kumar, Tarun - - 2012
Hemagiomas are most common tumors in infancy; however, scrotal septum hemangiomas are very rare with only 45 cases reported in the literature. We report a case of a 6 month old child who presented with a scrotal mass at birth which had increased in size with age.
Mercer, Christopher - - 2012
Introduction: Sudden death, particularly when occurring in children and adolescents, is a traumatic event not only for the victim's family, but for the entire community. It has been shown that school-based automated external defibrillator (AED) programs provide a high survival rate for both students and nonstudents who suffer sudden cardiac ...
Ibanez, Noel - - 2012
This is the case of a 44 year old man with frontotemporal lobar dementia whose presentation was consistent with Bipolar Affective Disorder with psychosis in addition to ongoing substance abuse. Despite extended periods of sobriety and multiple medications to target Bipolar Disorder, his symptoms remained refractory. With repeated brain imaging ...
Sedney, Cara - - 2012
Listeria monocytogenes is a known cause of meningitis, but cerebral abscess formation is exceedingly rare. We describe a patient who presented with an unsteady gait and a small ring-enhancing lesion in the right parietal lobe. Pathologic evaluation demonstrated an abscess with associated microglial nodules, and culture revealed Listeria. In spite ...
Lively, Mathew - - 2012
Objective: To detect a possible increasing trend in the annual prevalence of anterior cruciate ligament (ACL) injuries in a collegiate population and whether gender, sport, or year of the participant was predictive of a prior ACL injury.
Gaziano, Dominic - - 2012
Cater, MaryAnn - - 2012
1 2 3 4 5 6 7 8 9 10 >