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Results 351 - 400 of 1228
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Hacimustafaoglu, Mustafa - - 2010
Sarpel, Tunay - - 2010
Although tumor necrosis factor-alpha (TNF- [alpha]) antagonists are shown to be effective in the treatment of psoriasis, induction of psoriatic skin lesions have been seen in patients with different rheumatic conditions who were treated with TNF- [alpha] antagonists. In this case series, we report four cases that developed psoriatic lesions; ...
Paksoy, Fatma - - 2010
RS3PE (remitting seronegative, symmetric synovitis with pitting edema) is a benign, seronegative syndrome, with an acute onset of pitting edema on the dorsum of both hands and feet, which affects predominantly peripheral joints such as wrists and ankles symmetrically. A 58-year-old man presented with acute symmetrical polysynovitis of the wrists ...
Kulcu, Duygu - - 2010
Objective: To assess factors associated with pain and functional level in patients with knee osteoarthritis (OA).
Akin, Ceyda - - 2010
Objective: We aimed to assess the effectiveness of ultrasound treatment in patients with lateral epicondylitis and to compare with placebo ultrasound treatment.
- - 2010
Meng, Guoliang - - 2010
Embryonic stem cells (ESCs) are derived from the inner cell mass (ICM) of the blastocyst. Because of their ability to differentiate into a variety of cell types, human embryonic stem cells (hESCs) provide an unlimited source of cells for clinical medicine and have begun to be used in clinical trials. ...
Shahhoseini, Maryam - - 2010
Differentiation of stem cells from a pluripotent to a committed state involves global changes in genome expression patterns, critically determined by chromatin structure and interactions of chromatin-binding proteins. The dynamics of chromatin structure are lightly regulated by multiple epigenetic mechanisms such as histone modifications and the incorporation of histone variants. ...
Ong, Sang-Bing - - 2010
Chondrocytes, the resident cell-type of articular cartilage, are responsible for the regulation of the extracellular matrix (ECM) in response to their physico-chemical environment. Due to the nature of cartilage loading, chondrocytes are exposed to constant changes in extracellular osmolality with a gradual increase throughout the day. As an increase in ...
Ande, Sudharsana - - 2010
Plasma membrane translocation of specific cytosolic proteins plays an important role in cell signaling pathways. We have recently shown that prohibitin (PHB), a protein present in the plasma membranes of various cell types, interacts with Eps 15 homology domain protein 2 (EHD2), a lipid raft protein. However, the mechanism involved ...
Vonk, Lucienne - - 2010
Chondrocytes respond 10 glucose deprivation with a decreased collagen synthesis due lo disruption of a proper functioning of the endoplasmic reticulum (ER): ER stress. Since the mechanisms involved in the decreased synthesis are unknown, we have investigated whether chaperones and collagen-modifying enzymes are affected by glucose deprivation. Chondrocytes obtained from ...
Van Calsteren, - - 2010
The capsular polysaccharide (CPS) of Streptococcus suis serotype 2 was isolated, purified, chemically modified, and characterized. Sugar and absolute configuration analyses of the CPS gave the following composition: D-Gal, 3; D-Glc, 1: D-GlcNAc, 1; D-Neu5Ac, 1: L-Rha, 1. Sialic acid was found to be terminal, and the CPS was quantitatively ...
Liang, Pei - - 2010
Human YPEL4 is a member of YPEL family. II contains a Yippee domain, which is a putative zinc-finger-like, metal-binding domain. The human YPEL4 gene maps to chromosome 11q12.1, is ubiquitously expressed in adult tissues, and encodes a nuclear protein of 127 amino acids, the function of which remains unknown. To ...
Hemalatha, Thiagarajan - - 2010
Platelet-derived endothelial cell growth factor (PDECGF) is a potent angiogenic peptide with anti-apoptotic activity expressed widely in tumours. However, its expression in myocardial infarction (MI) is not yet established. This study aimed to assess the myocardial expression of PDECGF in rats after MI. Extracellular matrix (ECM) remodeling plays an important ...
Mandeville, J.S. - - 2010
Dietary constituents of fresh fruits and vegetables may play a relevant role in DNA adduet formation by inhibiting enzymatic activities. Studies have shown the important role of antioxidant vitamins A, C, and E in the protection against cancer and cardiovascular diseases. The antioxidant activity of vitamin A and beta-carotene may ...
Riou, Mickael - - 2010
In nematodes as in other eukaryotes, there is increasing evidence that drug resistance depends on both changes in the drug cellular targets and in nonspecific mechanisms, involving cellular detoxification by efflux pumps. In vertebrates, P-glycoproteins (Pgp) are membrane efflux pumps responsible for the elimination of xenobiotic agents, especially drugs. We ...
Craig, Douglas - - 2010
Assays were performed on individual Escherichia coli [beta]-galactosidase molecules at 2 different concentrations of the substrate DDAO-[beta]-D-galactoside using a free zone capillary electrophoresis-based protocol with an in- laboratory--constructed instrument utilizing laser-induced fluorescence detection. In a typical run. 2 enzyme molecules were injected into the capillary. They were separated from each ...
Summers, William - - 2010
Mitochondrial porin forms an aqueous pore in the outer membrane, through which selective passage of small metabolites and ions occurs, thereby regulating both mitochondrial function and cellular respiration. Investigations of the structure and function of porin have been performed with whole mitochondria, membrane vesicles, artificial membranes, and in detergent solutions, ...
MacLean, Leann - - 2010
The antigenic O-polysaccharide component of the lipopolysaccharide produced by Escherichia coli serolype O71:H12 was analyzed by chemical composition, nuclear magnetic spectroscopy, and Smith-type periodate oxidation methods. It was determined to be a partially Oacelylaled unbranched polymer of a repeating letrasaccharide unit composed of L-rhamnose, d-galactose, 2-acetamido-2-deoxy-d-galactose, and 3-acetamido-3-deoxy-l>-quinovose (1: 1: ...
Laway, Bashir - - 2010
Lactation failure is the first and the commonest manifestation of Sheehan's syndrome. We report the long-term follow-up of a patient with Sheehan's syndrome who presented with hyperprolactinemia rather than prolactin deficiency. A young woman developed Sheehan's syndrome after her 5th delivery, which was associated with severe postpartum hemorrhage. She presented ...
Ahmed, Shahid - - 2010
A 54-year-old man, banker by profession, presented with a three-year-history of generalized weakness, weight loss, fatigue, lethargy, irritability, decreased appetite, gastrointestinal symptoms, and sexual dysfunction. The symptoms had gradually and slowly worsened in the previous three years. He had suffered severe head injury due to road traffic accident 22 years ...
Arasil, Tansu - - 2010
Objective: To evaluate vitamin D status and its implications on bone metabolism in Ankara, Turkey.
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