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Aggarwal, Abha - - 2010
Background & objective: Estimation of disease burden due to leprosy by conventional sampling procedure is difficult due to large sample size requirement. In such situation, inverse sampling procedure could be a choice. A pilot study was undertaken to study the feasibility of adopting inverse sampling procedure over conventional sampling in ...
Khairkar, Praveen - - 2010
Background & objectives: It is difficult for a single investigator to study the psychosocial changes that occur over the life span of an individual affected with a chronic illness like [beta]-thalassaemia major. Therefore, a developmental epidemiological perspective is required to understand the chain of events and problems of psychological nature. ...
Sazawal, Sudha - - 2010
Background & objectives: The Janus-associated Kinase-2 mutation JAK2 V617F in chronic myeloproliferative disorders (CMPDs) has been described as a frequent genetic event in majority of patients with polycythemia vera (PV), essential thrombocythemia (ET) and idiopathic myelofibrosis (IMF). Its frequency varies in different populations but there are no data from India. ...
Ambade, Aditya - - 2010
Background & objectives: Prodrug activation strategy as well as immunotherapy have been widely used for cancer gene therapy. In the present study, using a head and neck squamous cell carcinoma (HNSCC) xenograft nude mouse model, we have investigated whether the two therapies in combination could improve tumour cell kill. We ...
Sharma, Hanish - - 2010
Background & objectives: No published data are available on neurocognitive dysfunction in Asian Indians with obstructive sleep apnoea (OSA). We therefore, studied the pattern and correlates of neurocognitive dysfunction in Indian adults with severe OSA.
Sharma, Prashant - - 2010
Background & objectives: The resistance of Mycobacterium tuberculosis to streptomycin, a core drug for treatment of category II tuberculosis (TB) has posed a major challenge to the health providers as well as research workers worldwide and has severely compromised the therapeutic options. A significant proportion of streptomycin resistant M. tuberculosis ...
Gurav, Yogesh - - 2010
Background & objectives: An outbreak of acute encephalitis syndrome (AES) among children from Nagpur division, Maharashtra was investigated to confirm the aetiology and to describe clinico-epidemiological features.
Kumar, A.K. - - 2010
Background & objectives: Simple and reliable methods to estimate drugs in pharmaceutical products are needed. In most cases, antiretroviral drug estimations are performed using a HPLC method, requiring expensive equipment and trained technicians. A relatively simple and accurate method to estimate antiretroviral drugs in pharmaceutical preparations is by spectrophotometric method, ...
Agarwal, Dipti - - 2010
Background & objectives: Zidovudine (ZDV) is the preferred nucleoside reverse transcriptase inhibitor in the first line antiretroviral regimen in India. It is known to be associated with life threatening toxicity like anaemia. This study was aimed at determining the prevalence of ZDV induced anaemia in HIV infected patients initiated on ...
Rajan, S. - - 2010
Background & objective: Renin-angiotensin aldosterone system (RAAS) plays an important role in the regulation of blood pressure. Aldosterone, synthesized by aldosterone synthase in the adrenal cortex is encoded by the CYP11B2 gene. In this case-control study we examined the association between CYP11B2 C-344T polymorphism and essential hypertension in south Indian ...
Anoop, Shajith - - 2010
The role of apolipoprotein E (apo E) in lipid metabolism and cholesterol transport is well established. About 14 per cent of the variation in plasma cholesterol levels is attributed to polymorphisms in APO E gene (APO E). APO E consists of three common alleles, designated as [epsilon]2, [epsilon]3 and [epsilon]4 ...
Sharma, Surendra - - 2010
Khullar, Madhu - - 2010
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Barrett, Gloria - - 2010
As the first baby boomers reach age 65 in 2011, California will face unprecedented growth in its aging population. At the same time, budget cuts threaten California s In-home Supportive Services (IHSS), which now assists seniors aging at home and the disabled. We conducted a cost analysis and compared caseload ...
Blackburn, Mary - - 2010
The silver century is now! Seniors 65 and older are the fastest growing segment of the world s population, and in the United States the 85 and over age group is increasing at the highest rate. This study documents the chronic diseases reported by a diverse group (n = 377) ...
Miller, Lisa M. - - 2010
Health literacy refers to the ability to read, understand and use health information to maintain or improve one s health. Health literacy skills have been linked to outcomes such as medication adherence, improved health and decreased health-care costs. Health literacy is particularly low among older adults. Given demographic projections that ...
Aldwin, Carolyn - - 2010
Although older adults are thought to experience more stress and to be more vulnerable to its adverse effects, they often report less stress than younger adults and sometimes show more resilience. Paradoxically, while stress sometimes has long-term positive effects on well-being, studies differ as to whether this increases or decreases ...
Ober, Beth - - 2010
A large body of evidence converges on the conclusion that episodic memory (the recollection of personally experienced events) is the only long-term memory system that shows significant age-related deficits. Moreover, the brain regions most likely to show age-related volume loss are those most critically involved in episodic memory. Older adult ...
Blackburn, Mary - - 2010
Inadequate diet and nutrition can contribute to or exacerbate chronic and acute diseases, hasten the development of degenerative diseases associated with aging, and delay recovery from illness. No single segment of society can benefit more from improved diet and nutrition, and regular exercise, than the elderly. While links between diet, ...
Allen-Diaz, Barbara - - 2010
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