Search Results
Results 351 - 400 of 837
< 3 4 5 6 7 8 9 10 11 12 13 >
Gieni, Randall - - 2009
Epigenetic programming is an important facet of biology, controlling gene expression patterns and the choice between developmental pathways. The Polycomb group proteins (PcGs) silence gene expression, allowing cells to both acquire and maintain identity. PcG silencing is important for stemness, X chromosome inactivation (XCI), genomic imprinting, and the abnormally silenced ...
Thambirajah, Anita - - 2009
There has been a hotbed of activity surrounding MeCP2 research in the past number of years. Despite better characterizing the functions and nature of this protein, it has become abundantly clear that MeCP2 is involved in far more complex activities than perhaps initially anticipated. Recent publications have shown that MeCP2 ...
Perez-Cadahia, Beatriz - - 2009
Chromatin condensation and subsequent decondensation are processes required for proper execution of various cellular events. During mitosis, chromatin compaction is at its highest, whereas relaxation of chromatin is necessary for DNA replication, repair, recombination, and gene transcription. Since histone proteins are directly complexed with DNA in the form of a ...
Fromm, George - - 2009
The [beta]-globin gene cluster in mammals, consisting of a set of erythroid-specific, developmentally activated, and (or) silenced genes, has long presented a model system for the investigation of gene regulation. As the number and complexity of models of gene activation and repression have expanded, so too has the complexity of ...
Harrison, Benjamin - - 2009
There are a number of well-characterized and fundamental roles for noncoding RNAs (ncRNAs) in gene regulation in all kingdoms of life. ncRNAs, such as ribosomal RNAs, transfer RNAs, small nuclear RNAs, small nucleolar RNAs, and small interfering RNAs, can serve catalytic and scaffolding functions in transcription, messenger RNA processing, translation, ...
Minks, Jakub - - 2009
X-chromosome inactivation is a fascinating epigenetic phenomenon that is initiated by expression of a noncoding (nc)RNA, XIST, and results in transcriptional silencing of 1 female X. The process requires a series of events that begins even before XIST expression, and culminates in an active and a silent X within the ...
Moser, Bettina - - 2009
Telomeres, the natural ends of linear chromosomes, must be protected and completely replicated to guarantee genomic stability in eukaryotic cells. However, the protected state of telomeres is not compatible with recruitment of telomerase, an enzyme responsible for extending telomeric G-rich repeats during S-phase; thus, telomeres must undergo switches from a ...
Filiz, E. - - 2009
Brachypodium distachyon (brachypodium) is a small grass with the biological and genomic attributes necessary to serve as a model system for all grasses including small grains and grasses being developed as energy crops (e.g., switchgrass and Miscanthus). To add natural variation to the toolkit available to plant biologists using brachypodium ...
Guo, Hong - - 2009
Differences in genome size and gene content are among the most important signatures of microbial adaptation and genome evolution. Here, we investigated the patterns of genome variation among 10 natural strains of the symbiotic nitrogen-fixing bacterium Sinorhizobium meliloti, using pulse field gel electrophoresis (PFGE) and whole-genome microarray hybridizations. Our PFGE ...
Trifonova, Anastassia - - 2009
Absence of spermiogenesis in mice with meiotic defects complicates the staging of meiotic arrest using light microscopy. Consequently, new methodologies are required to establish accurate relationships among germ cells. In this study, we utilized a novel approach to analyze germ cell degeneration in juvenile mice. We used terminal deoxynucleotidyl transferase ...
Gong, Xue - - 2009
Fifty-two SSR markers were used to evaluate the genetic diversity of 33 Qinghai-Tibetan wild barley accessions, 56 landraces collected primarily from other parts of China, and 1 Israeli wild barley accession. At the 52 SSR loci, 206 alleles were detected for the 90 accessions, among which 111 were common alleles. ...
Cavanna, M. - - 2009
There is a lack of published microsatellite data which characterizes Ribes spp. To address this, an initial study of simple sequence repeat (SSR) variation was undertaken in 41 cultivars belonging to four species of the genus Ribes to evaluate its genetic variability. The cultivars were collected in Piedmont, northwest Italy, ...
Dewitte, Angelo - - 2009
The genome sizes of a Begonia collection comprising 37 species and 23 hybrids of African, Asiatic, Middle American, and South American origin were screened using flow cytometry. Within the collection, 1C values varied between 0.23 and 1.46 pg DNA. Genome sizes were, in most cases, not positively correlated with chromosome ...
Olukolu, Bode - - 2009
Commercial production of apricot is severely affected by sensitivity to climatic conditions, an adaptive feature essential for cycling between vegetative or floral growth and dormancy. Yield losses are due to late winter or early spring frosts and inhibited vegetative or floral growth caused by unfulfilled chilling requirement (CR). Two apricot ...
Parker, John - - 2009
The use of psychiatric medication in patients with HIV infection is a complex area, but given the high rates of psychiatric disorder in this populationh--possibly as high as 50% (1)--it deserves further consideration. A number of issues need to be thought about, including the nature of both the psychiatric illness ...
Ogunrin, Olubunmi - - 2009
Objective. Information on the cognitive complications of HIV/AIDS from sub-Saharan Africa, where statistics on HIV are alarming, is sparse because of lack of validated cognitive tools. This study assessed the usefulness and predictive validity of the HIV Dementia Scale (HDS) as a screening tool in HIV-positive Nigerians.
Hoare, Jackie - - 2009
Advanced HIV disease is strongly associated with an increased occurrence of various neuropsychiatric disorders, (1) and highly active antiretroviral therapy (HAART) is an important aspect of managing these conditions effectively. (2) In addition, there is growing recognition that many HIV-infected individuals will develop neuropsychiatric disorders relatively early in the course ...
Singh, Dinesh - - 2009
Neurocognitive impairment (NCI) occurs in 10-60% of people living with HIV/AIDS (PLWHA), depending on the severity of the NCI and the stage of the disease. The clinical features and definitions have evolved over the past two decades. HIV-associated neurocognitive disorder (HAND) is a new term used to describe the spectrum ...
Boyles, Tom - - 2009
While HIV invades the brain early in the course of HIV infection, (1) severe mental illness probably only occurs later in the disease. (2) In many instances this may be the first presentation of a psychiatric illness in a younger person. In addition, the clinical syndrome may include manic and/or ...
Jonsson, G. - - 2009
The pathophysiology of psychosis and other forms of severe mental illness in HIV infection is complex, and multifactorial causation is likely in most instances. Severe mental illness has been identified as a risk factor for the acquisition of HIV infection and occurs as both a manifestation of opportunistic infections and ...
Pingo, Janine - - 2009
Women are disproportionately affected by the HIV epidemic and also carry a higher burden of early childhood trauma, other life traumas (e.g. rape and partner violence) and post-traumatic stress disorder (PTSD). (1,2) Yet PTSD and other common psychiatric disorders (e.g. depression, alcohol abuse) are commonly under-detected in HIV care settings. ...
Thom, Rita - - 2009
The term 'common mental disorders' is an overarching term for conditions that affect a significant number of people in the community. These conditions include depression, anxiety and substance use disorders. In contrast, so-called 'severe mental illnesses' (such as schizophrenia or bipolar mood disorder) are conditions that usually require admission for ...
Venter, Francois - - 2009
Bekker, Linda-Gail - - 2009
Alvarenga, Christiane - - 2009
Problem statement: The principal aim was to evaluate the effects of dengue virus infection by dengue during pregnancy and analyze the histopathology of the placenta. Approach: A retrospective study was conducted with 13 pregnant women with dengue confirmed in the period from January-December 2002, during a widespread dengue type 3 ...
Kofteridis, Diamantis - - 2009
Problem statement: Upper Respiratory Tract Infections (URTIs) are the most frequent of the community with major social and financial impact. Hence, early and proper diagnosis is of utmost importance. Biomarkers such as the circulating levels of Procalcitonin (PCT) have been shown to be elevated in systemic bacterial infections, but remain ...
Wan Norhasima, - - 2009
Problem statements: Fumonisin was a mycotoxin produced mainly by fungi belonging to the genus Fusarium in various foods and feeds. They occurred worldwide and were found predominantly in corn and in corn-based animal feeds and also can be found in other crops. Contamination of food and feed with fumonisins has ...
- - 2009
- - 2009
Nenninger, Steve - - 2009
Klotter, Jule - - 2009
Eslinger, Robert - - 2009
McDonagh, E.W. - - 2009
Creelman, Peggy - - 2009
- - 2009
< 3 4 5 6 7 8 9 10 11 12 13 >