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Gerlyand, Alexander - - 2009
Previous studies showed that amantadine transport increased while tetraethylammonium (TEA) transport decreased in kidney tissue from diabetic rats. Changes in transport activity were reversed by exogenous insulin. We hypothesized that this difference in transport regulation is due to differential regulation of different transport systems. Native human embryonic kidney cortex cells ...
Ludke, Ana R. - - 2009
Doxorubicin (Dox) is frequently used as a frontline chemotherapeutic agent against a variety of cancers. Tremendous progress has been made on its optimal usage over the last 40 years. However, cardiotoxicity still remains a major concern. The great promise in this matter is that the mechanisms leading to antitumor activity ...
Hauff, Kristin - - 2009
We examined whether cardiolipin (CL) synthesis was required to support cholesterol (CH) production from palmitate in Hela cells. Knockdown of human cardiolipin synthase-1 (hCLS1) in Hela cells has been shown to reduce CL synthesis. Therefore Hela cells stably expressing shRNA for hCLS1 and mock control cells were incubated for 16 ...
Halayko, Andrew - - 2009
Nearly 12% of children and 6% of adults in Canada have been diagnosed with asthma. Although in most patients symptoms are controlled by inhaled steroids, a subpopulation (~ 10%) characterized by excessive airway neutrophilia, is refractory to treatment; these patients exhibit severe disease, and account for more than 50% of ...
Zahradka, Peter - - 2009
Release of angiotensin II (AngII) after vascular injury promotes tissue repair by stimulating phenotypic modulation of smooth muscle cells, which enables cell proliferation and migration. This process requires cytoskeleton remodeling, which involves cortactin, a scaffold protein that is phosphorylated by Src kinase in response to Ang II. Since insulin-like growth ...
Makazan, Zhanna - - 2009
Repletion of [Ca.sup.2+] in the [Ca.sup.2+]-depleted heart has been shown to produce cardiac dysfunction, myocardial cell damage, intracellular [Ca.sup.2+] overload, and defects in sarcolemmal and sarcoplasmic reticulum function ([Ca.sup.2+] paradox). Although these alterations in the [Ca.sup.2+]-paradox heart are associated with a depression in the high-energy phosphate stores, little information regarding ...
Jiang, Zhi-Sheng - - 2009
Fibroblast growth factor 2 (FGF-2) is a multifunctional protein translated as high and low molecular weight isoforms (hi- and lo-FGF-2, respectively). Although the postconditioning cardioprotective effect of lo-FGF-2 (18 kDa) has been documented, hi-FGF-2 is less well studied. We used an isolated perfused rat heart model of ischemia-reperfusion to study ...
Kennedy, Stephenie - - 2009
Providing mobile screening mammography services across the state of West Virginia (WV) presents unique challenges. The ability of new machines to screen for breast cancer is modern medicine at its best. The use of the mobile unit, "Bonnie's Bus", holds promise for getting this high tech equipment to women in ...
Roth, Rebecca - - 2009
The State of West Virginia (WV) has significant cancer health disparities, substantiated by the fourth highest cancer mortality rate in the nation. In October 2007, Jo and Ben Statler donated $5 million dollars to the Mary Babb Randolph Cancer Center to establish a mobile mammography program (Bonnie's Bus) and endowed ...
Hatfield, Ginger - - 2009
This report describes several patients in whom diagnostic ultrasound played a significant role in the detection and diagnosis of breast masses. Diagnostic ultrasound was able to verify whether a breast mass was or was not present. Secondly, ultrasound was able to determine whether the mass was definitely benign and no ...
Brown, Pamela - - 2009
"Perspectives on Cancer Health Disparities in West Virginia" provides an overview of the factors that lead to health disparities in general, to the burden of breast and other cancers in our state, and highlights the deep-rooted values and characteristics that will help communities and their partners achieve parity.
Abraham, Jame - - 2009
In 2007, the American Cancer Society ranked West Virginia 43rd in breast cancer incidence rates for individual states. Despite our improvements in medical care, the advanced pathological characteristics of breast cancer at diagnosis receive little attention. Consequently, we compared the changing pattern of early breast cancer in several cohort studies ...
Tworek, Cindy - - 2009
Smoking has been increasingly identified as a risk factor for breast cancer among women. West Virginia has high rates of smoking, which can be further examined in relation to breast cancer screening and smoking related variables. This study used 2006 Behavioral Risk Factor Surveillance System (BRFSS) data to examine the ...
Kusminsky, Roberto - - 2009
Dean, Chad - - 2009
The National Comprehensive Cancer Network (NCCN) recommends that patients with ductal carcinoma in situ (DCIS) and stage I/II invasive breast cancer receive radiation therapy following breast conserving surgery (BCS). The purpose for our study was to determine 1) the percentage of patients with DCIS and stage I/II breast cancer who ...
Khanna, Rahul - - 2009
Situated entirely in the Appalachian region, West Virginia (WV) as a state is characterized by a diverse population, with a major portion of the population residing in rural areas. Breast cancer is the most commonly diagnosed cancer among women residents of the state. Using different data sources, we have reported ...
Rawson, Ashley - - 2009
Breast cancer affects many women, but with advances in detection and treatment, survival rates have increased. Thus, it is important to understand that there are many reconstructive options available to help ease the psychological burden of mastectomy. Reconstructive options include tissue expander/implants, biologics, and several autologous tissue options, including pedicled ...
Suppa, Carolyn - - 2009
While the field of psychosocial oncology has been recognized for several decades, specialized psychosocial services to West Virginians with cancer have been limited. Considering the increase in the incidence of cancer and the recognized burden of cancer-related emotional distress, healthcare providers must screen for emotional distress as the sixth vital ...
Abraham, Jame - - 2009
In the United States, mortality rates have been declining for certain tumors. For the majority of advanced stage cancer types, cure is unattainable but treatment is still evolving. Advances in the treatment of cancer can be achieved by enrolling patients in cancer clinical trials. Presently, less than 3% of adult ...
Sporck, F. - - 2009
Ratriyanto, A. - - 2009
This review focuses on the metabolic and osmoregulatory functions of betaine and its impact on nutrient digestibility and performance in pigs and poultry. Betaine is the trimethyl derivative of the amino acid glycine, and is present in plant and animal tissue. It has been shown to play an important role ...
Singh, N.K. - - 2009
Myogenic satellite cells have been isolated and identified by several recently elucidated molecular markers. Furthermore, knowledge about the precise function of these markers has provided insight into the early and terminal events of satellite cells during proliferation, differentiation, transdifferentiation, specification and activation. Recently, quiescent myogenic satellite cells have been associated ...
Wang, D.Y. - - 2009
Composition of intramuscular lipids, phospholipid classes and phospholipid molecular species in traditional Chinese duck meat products was investigated. Free fatty acids and phospholipids were identified and quantified by gas and high performance liquid chromatography, and phospholipid molecular species were determined by mass spectrometry. The results showed that raw duck meat ...
Higashiyama, Y. - - 2009
This study was performed to investigate the use of urinary catecholamines to monitor changes in the activity of the sympathetic nervous system and to determine the relationship of urinary cortisol and catecholamines in Japanese Shorthorn cows in response to social isolation. One cow was isolated from its group, which consisted ...
Sun, Y.G - - 2009
Adiponectin is an adipocyte-derived protein that has a regulatory role in energy homeostasis and influences insulin sensitivity. Its effects on glucose utilization and lipid metabolism are mediated by AdipoR1 and AdipoR2. How insulin affects adiponectin gene expression and secretion is still controversial. This study was conducted to determine the expression ...
Chao, Sun - - 2009
In this study we cloned and characterized a novel lipid-accumulating gene, the oxidized low-density lipoprotein receptor 1 (OLR1), which is associated with lipogenesis. We analyzed the gene structure and detected the mRNA transcriptional expression levels in pig adipose tissues at different months of age (MA) and in different economic types ...
Wang, M.Q. - - 2009
The study was conducted to evaluate the effects of trivalent chromium from different sources on growth, carcass composition, and serum parameters in finishing pigs. Ninety-six crossbred pigs with an initial average body weight of 65.57 [+ or -] 1.05 kg were blocked by body weight and randomly assigned to four ...
Seo, S.H. - - 2009
An experiment was conducted to investigate the effects of dietary supplementation of feather meal (FM) on the performance of pigs and taurine content in pork. A total of 135 cross-bred (LxYxD) pigs, weighing an average 46 kg, were assigned to five dietary treatments; Control, 3% FM supplemented diet (3% FM), ...
Song, Zhigang - - 2009
The effects of dietary copper (Cu) supplementation in broiler chickens challenged with a single injection of Salmonella typhymurium lipopolysaccharide (LPS) on the antioxidant capacity and plasma levels of ceruloplasmin (Cp) were evaluated. The broiler chickens were provided with a basal diet or diets supplemented with 8 and 50 mg/kg Cu ...
Yan, L. - - 2009
Two hundred and sixteen 68-week-old Hy-Line brown laying hens were used in a 6-week feeding trial to compare the efficacy of phytases Optiphos (OPT) and Natuphos (NAT), which were isolated from Escherichia coli and Aspergillus niger, respectively. Hens were randomly allotted into six treatments with six replications (six layers in ...
Xie, Ming - - 2009
A dose-response experiment with five lysine levels (0.65, 0.80, 0.95, 1.10, and 1.25%) was conducted to evaluate the lysine requirement of male White Pekin ducklings from 7 to 21 days of age. Two hundred and eighty, 7-day-old, male White Pekin ducklings were allocated to 5 experimental treatments, each containing 8 ...
Laudadio, V. - - 2009
Effect of inclusion of hard vs. soft wheat bran with different particle size on diet digestibility, growth performance and some slaughter traits was evaluated in fattening rabbits. Four isonitrogenous and isocaloric diets were used according to the origin of wheat bran (hard (HWB)--Triticum durum--and soft (SWB)--Triticum aestivum) combined with wheat ...
Promkot, C. - - 2009
Effect of sulfur (S) on utilization efficiency of fresh cassava foliage and cassava hay in dairy cows was evaluated using thirty-two 1st-2nd lactation Holstein-Friesian crossbred dairy cows. The experimental treatment was a 2x2 factorial arrangement in a randomized complete block design (RCBD) using two roughages (rice straw+fresh cassava foliage (FCF) ...
Uemoto, Y. - - 2009
We performed a genome-wide linkage and quantitative trait locus (QTL) analysis to confirm the existence of QTL affecting Rous Sarcoma Virus (RSV) induced tumor regression, and to estimate their effects on phenotypic variance in an F2 resource population. The F2 population comprised 158 chickens obtained by crossing tumor regressive White ...
Honda, Takeshi - - 2009
Parentage tests using polymorphic DNA marker are commonly performed to avoid incorrect recording of the parental information of livestock animals, and single-nucleotide polymorphisms (SNPs) are becoming the method of choice. In Japanese Black cattle, parentage tests based on the exclusion method using microsatellite markers are currently conducted; however, an alternative ...
Saleh, D. - - 2009
Dog bites are a common presentation to emergency departments worldwide. However, presenting symptoms may fail to reveal the severity of an injury. We present such a case.
Fahl, Kelly - - 2009
It has been reported that patients with bladder cancer have widely varying paraneoplastic consequences, including metabolic, dermatologic, myopathic and neurologic disturbances. We report a case of a 52-year-old man with advanced transitional cell carcinoma and liver metastases, who developed a severe coagulopathy following robotic radical cystoprostatectomy due to circulating heparin-like ...
Andreoiu, Matei - - 2009
We report on a very large renal leiomyoma in a man presenting with a 1-year history of lower back and flank pain and a rapidly growing abdominal mass. Since a cystic renal cell carcinoma could not be ruled out, a postembolization right radical nephrectomy was performed. Diagnosis was confirmed by ...
Greene, Graham - - 2009
The surgical anatomy of a horseshoe kidney (HK) is unique in many ways, ranging from its anomalous circulation, shared renal parenchyma between the right and left renal moieties, and its anterior renal pelvis, to the fact that it obscures access to the vena cava and aorta. While renal cell carcinomas ...
Casey, Rowan - - 2009
There are only 7 cases reported in the literature of squamous cell cancer of the bladder in patients performing intermittent self-catheterization (ISC). We report on an eighth case, and the first case described in a patient with a Mitrofanoff continent appendicovesicostomy. A description of the case and review of the ...
Rasmussen, Nathan - - 2009
Sacral neuromodulation has become a standard minimally invasive therapy for refractory urinary urge/frequency and urge incontinence. Prior to the widespread use of sacral neuromodulation, augmentation cystoplasty was a standard treatment for refractory overactive bladder (OAB). The use of sacral neuromodulation following bladder augmentation has not been previously reported in the ...
Chen, C-H. - - 2009
A 64-year-old man presented with gross painless hematuria. Cystoscopy revealed a submucosal bladder neck mass covered by normal urothelium. During transurethral resection, the patient developed hemodynamic crisis including sinus bradycardia. Histopathologic examination revealed a primary bladder composite paraganglioma-ganglioneuroma (CPG). The patient underwent partial cystectomy and is symptom-free after one year. ...
Hallock, Abhirami - - 2009
A 53-year-old man with a 14-year history of renal cell carcinoma (RCC) presented with a 2-month history of right-sided upper jaw pain and severe bleeding during tooth extraction. Pathology review of a lower maxillary sinus/upper gingival mass revealed metastatic RCC. The presentation, differential diagnosis and literature review of this uncommon ...
Blank, Steven - - 2009
We used 11 years of data from video auction sales across the western United States to address two long-standing questions posed by California cattle ranchers. First, as expected, ranchers receive lower prices for cattle sold here compared to prices received by ranchers in the Midwest. Second, some (but not all) ...
Zhong, Liheng - - 2009
Most agricultural systems in California s Central Valley are purposely flexible and intentionally designed to meet the demands of dynamic markets such as corn, tomatoes and cotton. As a result, crops change annually and semiannually, which makes estimating agricultural water use difficult, especially given the existing method by which agricultural ...
Forero, Larry - - 2009
We used data from 4-H record books to evaluate the 4-H programs in Shasta and Trinity counties. These books are completed annually by youth participants throughout California to describe and quantify their experiences in the program and reflect on their involvement in citizenship, leadership and life-skills activities. Quantitative and qualitative ...
Carlos, Ramona - - 2009
Teenage drivers, particularly new drivers, have higher crash rates than adults. We surveyed 2,144 teenage drivers in California about their driving practices, factors influencing driving behavior, and views on driver education and resources. Teens wanted updated driver education courses and more behind-the-wheel training while learning to drive. They identified parents ...
Kaffka, Stephen - - 2009
The use of crops and crop residues as feedstocks for biofuels increases domestic and global supplies, creates new industries, and may result in reduced greenhouse-gas emissions. Uncertainty about the best crop and residue sources, technologies for manufacture, future public policy, and the global supply and price of oil make it ...
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