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Odze, Robert - - 2008
* Context.--At present, Barrett esophagus is the most common cause of esophageal adenocarcinoma. In the past 20 years, the incidence of esophageal adenocarcinoma in white males has exceeded that of tumors of the colorectum, lung, prostate, and skin.
Lee, Walter - - 2008
* Context.--Head and neck squamous cell carcinoma is commonly associated with tobacco and alcohol use. There are, however, a group of patients without a significant history of tobacco or alcohol use, and the etiology of these tumors is incompletely understood.
Murer, Bruno - - 2008
* Context.--The development of targeted therapy provides an exciting prospect for treatment of advanced non-small cell lung cancer. In the last few years the epithelial growth factor receptor has emerged as one of the most important targets in very selected patients.
Sanchez-Cespedes, Montserrat - - 2008
* Context.--The development of targeted therapies creates a need to accurately classify tumors. Among the more pressing needs are the identification of the complete catalog of genes that are altered in cancer and the accurate discrimination of tumors based on their genetic background.
Dighe, Anand - - 2008
* Context.--Reporting of laboratory critical values has become an issue of national attention because of important regulatory, medicolegal, and clinical concerns.
Wagar, Elizabeth - - 2008
* Context.--Accurate specimen identification is critical for quality patient care. Improperly identified specimens can result in delayed diagnosis, additional laboratory testing, treatment of the wrong patient for the wrong disease, and severe transfusion reactions. Specimen identification errors have been reported to occur at rates of 0.1% to 5%.
Perper, Joshua - - 2008
Context.--The investigation of high-profile fatalities poses special challenges to medical examiners and coroners. Most high-profile cases can be readily recognized early in the course of the investigation. Commonly encountered examples include police-related fatalities or deaths in custody, deaths of celebrities, and mass fatalities or clustered deaths (eg, serial killers). Medical ...
Viswanathan, Seethalakshmi - - 2008
We describe an extremely rare occurrence of a squamous differentiation in a sarcomatoid chromophobe renal cell carcinoma in a 45-year-old woman with nodal and lung metastasis at presentation. The tumor on histology showed all 3 components intimately admixed with each other, which to the best of our knowledge is the ...
Goldsmith, Jeffrey - - 2008
Context.--The surgical pathology report (SPR) is an essential part of patient care because it documents the pathologic findings in tissues removed from patients for diagnostic or therapeutic reasons. Despite the importance of the SPR, exhaustive guidelines outlining the various elements of the SPR have not, to our knowledge, been published.
Fredricks, Jennifer Rose - - 2008
Primary malignant melanoma of the esophagus (PMME) is a rare neoplasm. The primary nature of esophageal melanoma has been questioned in the past because most reported cases have not been able to demonstrate local tumorigenesis or evolution of the malignancy from a preceding benign lesion or cell. In addition, the ...
Siddiqui, Momin - - 2008
Context.--Papanicolaou tests with atypical squamous cells of undetermined significance (ASC-US) cytology and adjunct testing for high-risk human papillomaviruses (hr-HPV) are helpful in detecting high-grade disease. Detection of disease may be further improved with molecular markers known to be overexpressed in cervical carcinoma. ProEx C detects 2 such molecular markers, minichromosome ...
Sepulveda, Antonia - - 2008
Context.--Most types of gastritis can be diagnosed on hematoxylin-eosin stains. The most common type of chronic gastritis is Helicobacter pylori gastritis. Reactive or chemical gastropathy, which is often associated with nonsteroidal anti-inflammatory drug use or bile reflux, is common in most practices. The diagnosis of atrophic gastritis can be challenging ...
Wisniewski, Jacek - - 2008
* Mass spectrometry-based proteomics is a modern and rapidly developing methodology for qualitative and quantitative characterization of proteins and their posttranslational modification, subcellular localization, and interaction partners. It enables characterization of entire proteomes with unprecedented sensitivity and precision, providing platforms for identification of biomarkers and drug targets.
Petrolla, Amber - - 2008
* Hepatic angiomyolipoma is a rare, benign, hepatic mesenchymal neoplasm found in both males and females, and most commonly in adult females. Angiomyolipoma occurs most commonly in the kidneys. The liver represents the second most frequent site of involvement. Hepatic angiomyolipomas are composed of varying amounts of smooth muscle cells, ...
Upton, Melissa - - 2008
* Context.--Celiac sprue affects genetically susceptible individuals, who develop small intestinal injury and malabsorption following dietary exposure to gluten. The histologic features are nonspecific but characteristic.
Youens, Kenneth - - 2008
* Extranodal follicular dendritic cell sarcoma is a rare tumor of follicular dendritic cells that can occur in a wide variety of sites. Although fairly well characterized histologically, with a distinct immunophenotype, it remains underrecognized, with as many as one third of cases initially misdiagnosed. This is often due to ...
Giltnane, Jennifer - - 2008
* Context.--Selection for trastuzumab therapy depends on a companion diagnostic assessment of HER2 by either immunohistochemistry (IHC) for protein overexpression or fluorescence in situ hybridization (FISH) to detect gene amplification. Although many studies have compared IHC to FISH, few have compared the tests to the true gold standard, tumor response.
Sanchez, Amy - - 2008
* Context.--Primary esophageal melanoma (PEM) is a rare disease and is difficult to distinguish from other esophageal malignancies and from metastatic melanoma.
Lee, Sun - - 2008
* Context.--CpG island methylator phenotype (CIMP) designates a subset of colorectal cancers featuring concordant hypermethylation of multiple promoter CpG islands. Little is known about the clinical outcome or histologic characteristics of CIMP-positive colorectal cancers defined by recently identified CpG island methylator phenotype panels.
Washington, Mary - - 2008
* Context.--Colorectal carcinoma is one of the most common types of cancer in Western countries and is consistently ranked among the top 3 causes of cancer-related deaths, with approximately 150 000 new cases in the United States and 55 000 deaths in 2006. The pathologist's assessment of tumor stage and ...
Allen, Timothy - - 2008
Muradyan, Artur - - 2008
The accumulation of chromosomal aberrations is a characteristic feature of tumor development. However, an understanding of tumorigenesis that assumes that changes in DNA copy number always cause equivalent changes in the corresponding RNA and protein levels is an oversimplification and completely ignores the individual genetic and epigenetic context in which ...
Onyejekwe, Chineze - - 2008
Phillips, C. - - 2008
Dallessio, Kathleen - - 2008
Shaheen, Feroze - - 2008
Modupe, Fasoranti - - 2008
The study examined the economic implication of COWAN poverty alleviation programme in rural women. Multi-stage sampling technique was used to select 100 respondents from Ikare and Ugbe from Akoko North East and Oka and Akungba from Akoko South West. The data collected were analysed with the aid of descriptive statistics ...
Amini, Mitra - - 2008
Problem statement: The aim of the present study was to determine the successful medical students' viewpoints on factors significant to their academic success assessed according to the students' grade point average. In this research the students with the grade point average (GPA) A (17-20) were considered academically successful. Approach: The ...
Pothisan, Wilart - - 2008
The state had paid much attention on economy by building a network of roads between the province, the district and the village for the Kuy people in Ban Treum. The state established a health center to provide for the people with modern medical care and malaria prevention. And the external ...
Adetunde, I.A. - - 2008
This study presents the current factors affecting the standard of female education in the Kassena-Nankana district in Upper East Region of Ghana. Poverty, long-held negative attitudes about women's intellectual capabilities, teenage pregnancy, early marriage, examination failure in mathematics and science and the traditional division of household labour are among the ...
Sata, Winyoo - - 2008
Problem statement: The objective of this research was to study the environment change of Lampao Dam communities in Northeast Thailand, being a case study of the Sa-Adnathom community, Lamklong sub-district, Muang, Kalasin province, adjacent to the Lampao Dam. Approach: A qualitative research, it started with a review of literature and ...
Sarlak, Mohammad - - 2008
Currently there are 24 free trade and special economic zones in Iran. Problem Statement: of these zones is lack of e-business and this is in spite of managements' desire to have proper infrastructure for e-business in these zones. The goal of this study is to determine and explain e-business barriers ...
Kumar, Naresh - - 2008
Problem statement: Studies on cultural intelligence (CQ) have been recently initiated dramatically in an effort to determine how they were related to positive life outcomes. While past findings showed positive correlations to various aspects of life outcomes, clear establishments of the theoretical and empirical connections of CQ on cross-cultural adjustment ...
Mukherjee, Indranil - - 2008
Problem Statement: Failure of computer based information systems had been a source of major concern in the modern technological era. Information System (IS) researchers have spent a significant amount of their time and effort in understanding the recurring failure of Information Systems. Studies in this regard have ranged from being ...
Awwad, Abdulkareem - - 2008
Problem statement: The motivation for this study is determining the extent that modification flexibility affects positively the achievement of strategic and operational objectives in the context of Jordanian manufacturing companies. It addresses the relationship between modification flexibility and organizational objectives. Approach: to tackle the problem statement, the positivistic paradigm was ...
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