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Marsh, Ann - - 2008
Pacemaker technology has advanced rapidly over the last decade. A lot of everyday interference can be regarded as transient. The media tend to cover stories of relatively insignificant transient interference incurred by pacemaker wearers while many manuals gloss over the high risks, some potentially life-threatening. These include the reliability of ...
Kannan, Anand - - 2008
Using heparinised saline as a flush to maintain the patency of arterial and central venous lines is a well-known practice. A literature search was undertaken but found no evidence to support the use of heparinised saline over normal saline. In addition, the use of heparinised saline may be associated with ...
Ellis, Harold - - 2008
Nowadays well over half the new graduates coming out of the medical schools in the United Kingdom are women. Women are found in the highest ranks in the profession and are well represented on the Councils of the Royal Colleges and the other medical institutions. Yet it was only during ...
Durai, Rajaraman - - 2008
Vacuum-assisted closure (VAC) wound dressing is increasingly used to assist closure in various wounds ranging from simple finger pulp defect to complex wounds such as laparostomy or infected sternotomy. The traditional application of direct vacuum therapy can cause discomfort and put the patient at risk of injuring the affected area ...
Clark-Burg, Karen - - 2008
An Australian College of Operating Room Nurses (ACORN) submission (ACORN 2002-2008) recently stated that the specialities that suffered significantly from the transition of hospital-based nursing training to university training were the perioperative specialty, critical care and emergency. The main reason for this was that perioperative nursing was not included in ...
Kim, Jeong - - 2008
Pathological angiogenesis in the eye is the most common cause of blindness in all age groups. In physiological and pathological cellular processes including angiogenesis, ion homeostasis is greatly affected. This study is to investigate the role of calcium ion in physiological and pathological angiogenesis in the retina, which is based ...
Musse, Abdiwahab - - 2008
Multiple sclerosis is a complex human neurodegenerative disease, characterized by the active destruction of the insulating myelin sheath around the axons in the central nervous system. The physical deterioration of myelin is mediated by hyperdeimination of myelin basic and other proteins, catalysed by the [Ca.sup.2+]-dependent enzyme peptidylarginine deiminase 2 (PAD2). ...
Kota, Swathi - - 2008
An efficient DNA strand break repair contributes to the radioresistance of Deinococcus radiodurans, which harbors the DNA repair pathways nearly identical to Escherichia coli. The molecular mechanisms of these proteins functioning in 2 diverse classes of bacteria seem to be different. The macromolecular interactions and formation of multiprotein complexes in ...
Rousselet, Estelle - - 2008
Disruption of iron homeostasis at the levels of intestinal absorption or erythropoiesis contributes to cadmium toxicity. Cellular iron homeostasis in metazoans is maintained by the iron regulatory proteins (IRPs) that regulate the synthesis of proteins involved in the transport, use, and storage of iron. The effect of cadmium intoxication on ...
Lin, Jijin - - 2008
Protein-protein interaction plays a key role in the regulation of biological processes. The human potassium (HERG) channel is encoded by the ether-a-go-go-related gene (herg), and its activity may be regulated by association with other cellular proteins. To identify cellular proteins that might play a role in the regulation of the ...
Bani-Yaghoub, Mahmud - - 2008
Every year thousands of people suffer from brain injuries and stroke, and develop motor, sensory, and cognitive problems as a result of neuronal loss in the brain. Unfortunately, the damaged brain has a limited ability to enact repair and current modes of treatment are not sufficient to offset the damage. ...
Box, Adrian - - 2008
The mechanisms by which cells undergo proliferation arrest or cell death in response to hypoxia are still not completely understood. Originally, we showed that HeLa and Hep3B carcinoma cells undergo different proliferation responses in hypoxia. We now show that these 2 cell lines also have different cell death responses to ...
Derlacz, Rafal - - 2008
Therapeutic effect of rosiglitazone has been reported to result from an improvement of insulin sensitivity and inhibition of glucose synthesis. As the latter process occurs in both liver and kidney cortex the aim of this study was to elucidate the rosiglitazone action on glucose formation in both tissues. Primary cultured ...
Qi, Qi. - - 2008
Gambogic acid (GA) has been known to have antitumor activity in vitro and in vivo. In the present study, we investigated the anti-invasive effects of GA in MDA-MB-231 human breast carcinoma cells. The results indicated that GA significantly inhibited the adhesion, migration, and invasion of the cells in vitro tested ...
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